SG11202001925WA - Substituted imidazoquinolines - Google Patents

Substituted imidazoquinolines

Info

Publication number
SG11202001925WA
SG11202001925WA SG11202001925WA SG11202001925WA SG11202001925WA SG 11202001925W A SG11202001925W A SG 11202001925WA SG 11202001925W A SG11202001925W A SG 11202001925WA SG 11202001925W A SG11202001925W A SG 11202001925WA SG 11202001925W A SG11202001925W A SG 11202001925WA
Authority
SG
Singapore
Prior art keywords
substituted imidazoquinolines
imidazoquinolines
substituted
Prior art date
Application number
SG11202001925WA
Other languages
English (en)
Inventor
Christophe Henry
Original Assignee
BioNTech SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BioNTech SE filed Critical BioNTech SE
Publication of SG11202001925WA publication Critical patent/SG11202001925WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11202001925WA 2017-09-06 2018-08-31 Substituted imidazoquinolines SG11202001925WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2017/072352 WO2019048036A1 (en) 2017-09-06 2017-09-06 SUBSTITUTED IMIDAZOQUINOLINES
PCT/EP2018/073470 WO2019048350A1 (en) 2017-09-06 2018-08-31 SUBSTITUTED IMIDAZOQUINOLINES

Publications (1)

Publication Number Publication Date
SG11202001925WA true SG11202001925WA (en) 2020-04-29

Family

ID=59914433

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202001925WA SG11202001925WA (en) 2017-09-06 2018-08-31 Substituted imidazoquinolines

Country Status (16)

Country Link
US (2) US11267813B2 (pt)
EP (1) EP3679038B1 (pt)
JP (1) JP7241738B2 (pt)
KR (1) KR20200050963A (pt)
CN (1) CN111094287A (pt)
AU (1) AU2018327414B2 (pt)
BR (1) BR112020004504A2 (pt)
CA (1) CA3074166A1 (pt)
DK (1) DK3679038T3 (pt)
FI (1) FI3679038T3 (pt)
IL (1) IL273002B2 (pt)
MX (1) MX2020002367A (pt)
RU (1) RU2768629C2 (pt)
SG (1) SG11202001925WA (pt)
WO (2) WO2019048036A1 (pt)
ZA (2) ZA202001266B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202001926QA (en) * 2017-09-06 2020-04-29 BioNTech SE Substituted imidazoquinolines as agonists of tlr7
WO2019048036A1 (en) * 2017-09-06 2019-03-14 Biontech Ag SUBSTITUTED IMIDAZOQUINOLINES
EP3935047A1 (en) * 2019-03-07 2022-01-12 BioNTech SE Process for the preparation of a substituted imidazoquinoline
WO2021086689A1 (en) * 2019-10-29 2021-05-06 Prime Reach Trading Limited 4-amino-imidazoquinoline compounds and use thereof
WO2023083439A1 (en) * 2021-11-09 2023-05-19 BioNTech SE Tlr7 agonist and combinations for cancer treatment

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS585623B2 (ja) 1976-07-12 1983-02-01 日本電信電話株式会社 ファクシミリ通信方式
US6573273B1 (en) 1999-06-10 2003-06-03 3M Innovative Properties Company Urea substituted imidazoquinolines
US6451810B1 (en) 1999-06-10 2002-09-17 3M Innovative Properties Company Amide substituted imidazoquinolines
US6756382B2 (en) 1999-06-10 2004-06-29 3M Innovative Properties Company Amide substituted imidazoquinolines
US6677349B1 (en) 2001-12-21 2004-01-13 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines
CA2480800C (en) 2002-04-08 2008-09-23 Mark T. Bilodeau Inhibitors of akt activity
WO2005051324A2 (en) 2003-11-25 2005-06-09 3M Innovative Properties Company Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
AU2005283085B2 (en) * 2004-06-18 2012-06-21 3M Innovative Properties Company Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
AU2006311871B2 (en) * 2005-11-04 2011-03-03 3M Innovative Properties Company Hydroxy and alkoxy substituted 1H-imidazoquinolines and methods
BRPI0807893A2 (pt) 2007-02-20 2014-06-17 Novartis Ag Imidazoquinolinas como inibidores duais de lipídio quinase e mtor.
PL2155743T3 (pl) * 2007-05-08 2013-01-31 Astrazeneca Ab Imidazochinoliny o właściwościach immunomodulacyjnych
DK2386557T3 (en) * 2008-03-24 2018-04-23 Biontech Ag Newly substituted imidazoquinolines
WO2010119264A1 (en) 2009-04-16 2010-10-21 Centro Nacional De Investigaciones Oncólogicas (Cnio) Imidazopyrazines for use as kinase inhibitors
CN103012398B (zh) 2011-09-19 2015-10-14 上海恒瑞医药有限公司 咪唑并喹啉类衍生物及其可药用盐、其制备方法及其在医药上的应用
SG11202001926QA (en) * 2017-09-06 2020-04-29 BioNTech SE Substituted imidazoquinolines as agonists of tlr7
WO2019048036A1 (en) * 2017-09-06 2019-03-14 Biontech Ag SUBSTITUTED IMIDAZOQUINOLINES

Also Published As

Publication number Publication date
US20220227756A1 (en) 2022-07-21
RU2020112229A (ru) 2021-10-06
WO2019048350A1 (en) 2019-03-14
JP7241738B2 (ja) 2023-03-17
IL273002B2 (en) 2023-08-01
JP2020532570A (ja) 2020-11-12
US20200317663A1 (en) 2020-10-08
AU2018327414B2 (en) 2024-02-15
BR112020004504A2 (pt) 2020-09-15
EP3679038A1 (en) 2020-07-15
IL273002B1 (en) 2023-04-01
KR20200050963A (ko) 2020-05-12
DK3679038T3 (da) 2024-05-27
ZA202101322B (en) 2022-09-28
IL273002A (en) 2020-04-30
EP3679038B1 (en) 2024-04-03
RU2020112229A3 (pt) 2021-10-06
AU2018327414A1 (en) 2020-03-19
WO2019048036A1 (en) 2019-03-14
US11267813B2 (en) 2022-03-08
CA3074166A1 (en) 2019-03-14
MX2020002367A (es) 2020-07-20
ZA202001266B (en) 2021-08-25
FI3679038T3 (fi) 2024-05-23
CN111094287A (zh) 2020-05-01
RU2768629C2 (ru) 2022-03-24

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