SG11201909618TA - Compositions and methods for library construction and sequence analysis - Google Patents
Compositions and methods for library construction and sequence analysisInfo
- Publication number
- SG11201909618TA SG11201909618TA SG11201909618TA SG11201909618TA SG 11201909618T A SG11201909618T A SG 11201909618TA SG 11201909618T A SG11201909618T A SG 11201909618TA SG 11201909618T A SG11201909618T A SG 11201909618TA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- international
- compositions
- kits
- rule
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/50—Other enzymatic activities
- C12Q2521/501—Ligase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/191—Modifications characterised by incorporating an adaptor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/122—Massive parallel sequencing
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Structural Engineering (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Sampling And Sample Adjustment (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Polyurethanes Or Polyureas (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762487423P | 2017-04-19 | 2017-04-19 | |
| US201862657544P | 2018-04-13 | 2018-04-13 | |
| PCT/US2018/028191 WO2018195217A1 (en) | 2017-04-19 | 2018-04-18 | Compositions and methods for library construction and sequence analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201909618TA true SG11201909618TA (en) | 2019-11-28 |
Family
ID=63856830
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202111266VA SG10202111266VA (en) | 2017-04-19 | 2018-04-18 | Compositions and methods for library construction and sequence analysis |
| SG11201909618T SG11201909618TA (en) | 2017-04-19 | 2018-04-18 | Compositions and methods for library construction and sequence analysis |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202111266VA SG10202111266VA (en) | 2017-04-19 | 2018-04-18 | Compositions and methods for library construction and sequence analysis |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11965157B2 (zh) |
| EP (1) | EP3612641A4 (zh) |
| JP (1) | JP7220200B2 (zh) |
| KR (1) | KR102601593B1 (zh) |
| CN (1) | CN110770354B (zh) |
| AU (1) | AU2018256387A1 (zh) |
| CA (1) | CA3060555A1 (zh) |
| SG (2) | SG10202111266VA (zh) |
| TW (1) | TWI797118B (zh) |
| WO (1) | WO2018195217A1 (zh) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019234843A1 (en) | 2018-03-13 | 2020-09-24 | Grail, Llc | Anomalous fragment detection and classification |
| AU2019249422A1 (en) | 2018-04-02 | 2020-10-15 | Grail, Llc | Methylation markers and targeted methylation probe panels |
| WO2020033238A1 (en) * | 2018-08-07 | 2020-02-13 | Singlera Genomics, Inc. | A non-invasive prenatal test with accurate fetal fraction measurement |
| CA3111887A1 (en) | 2018-09-27 | 2020-04-02 | Grail, Inc. | Methylation markers and targeted methylation probe panel |
| CN112080555A (zh) * | 2019-06-14 | 2020-12-15 | 上海鹍远健康科技有限公司 | Dna甲基化检测试剂盒及检测方法 |
| CN110964782A (zh) * | 2019-12-09 | 2020-04-07 | 上海鹍远健康科技有限公司 | 单链核酸连接效率检测方法 |
| CN111321208B (zh) * | 2020-02-14 | 2023-10-03 | 上海厦维医学检验实验室有限公司 | 一种基于高通量测序的建库方法 |
| MX2021015806A (es) * | 2020-02-26 | 2022-04-27 | Illumina Inc | Kits para genotipificacion. |
| CN111979583B (zh) * | 2020-09-10 | 2023-09-12 | 杭州求臻医学检验实验室有限公司 | 一种单链核酸分子高通量测序文库的构建方法及其应用 |
| WO2022181858A1 (ko) * | 2021-02-26 | 2022-09-01 | 지니너스 주식회사 | 분자 바코딩 효율을 향상시키기 위한 조성물 및 이의 용도 |
| KR20220122095A (ko) | 2021-02-26 | 2022-09-02 | 지니너스 주식회사 | 분자 바코딩 효율을 향상시키기 위한 조성물 및 이의 용도 |
| WO2023201487A1 (zh) * | 2022-04-18 | 2023-10-26 | 京东方科技集团股份有限公司 | 接头、接头连接试剂及试剂盒和文库构建方法 |
| WO2024015869A2 (en) * | 2022-07-12 | 2024-01-18 | University Of Washington | Systems and methods for variant detection in cells |
| KR20240085399A (ko) * | 2022-12-08 | 2024-06-17 | 광주과학기술원 | Dna 단편의 멀티 결합 조립 반응을 이용한 단일세포의 다중체 전장 시퀀싱 분석방법 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004284456B2 (en) | 2003-10-21 | 2012-04-19 | Orion Genomics Llc | Methods for quantitative determination of methylation density in a DNA locus |
| WO2006113770A1 (en) | 2005-04-15 | 2006-10-26 | Epigenomics Ag | A method for providing dna fragments derived from a remote sample |
| KR20080011287A (ko) | 2005-04-15 | 2008-02-01 | 에피제노믹스 아게 | 세포 증식 질환을 분석하기 위한 방법 및 핵산 |
| US7582405B2 (en) | 2005-10-26 | 2009-09-01 | Hewlett-Packard Development Company, L.P. | Image recording media and image layers |
| GB0522310D0 (en) * | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
| US7901882B2 (en) | 2006-03-31 | 2011-03-08 | Affymetrix, Inc. | Analysis of methylation using nucleic acid arrays |
| US20080261217A1 (en) | 2006-10-17 | 2008-10-23 | Melnikov Anatoliy A | Methylation Profile of Cancer |
| WO2011109529A1 (en) | 2010-03-03 | 2011-09-09 | Zymo Research Corporation | Detection of dna methylation |
| WO2012106525A2 (en) | 2011-02-02 | 2012-08-09 | Exact Sciences Corporation | Digital sequence analysis of dna methylation |
| BR112014000443B1 (pt) | 2011-07-08 | 2021-03-23 | Epigenomics Ag | Métodos para determinação do prognóstico de um indivíduo com câncer |
| CA2872867C (en) | 2012-05-11 | 2020-09-15 | Clinical Genomics Pty Ltd | Diagnostic gene marker panel for colorectal cancer |
| US20150011396A1 (en) * | 2012-07-09 | 2015-01-08 | Benjamin G. Schroeder | Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing |
| US20140093873A1 (en) | 2012-07-13 | 2014-04-03 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| US10482994B2 (en) | 2012-10-04 | 2019-11-19 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US10179933B2 (en) | 2013-02-07 | 2019-01-15 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Hybrid nanopores and uses thereof for detection of analytes |
| EP2959016A4 (en) * | 2013-02-21 | 2016-10-12 | Toma Biosciences Inc | METHOD, COMPOSITIONS AND NUCLEIC ACID ANALYSIS KITS |
| WO2014160199A1 (en) | 2013-03-14 | 2014-10-02 | Cornell University | Method for relative quantification of changes in dna methylation, using combined nuclease, ligation, and polymerase reactions |
| ES2812753T3 (es) | 2014-03-31 | 2021-03-18 | Mayo Found Medical Education & Res | Detección de neoplasma colorectal |
| US11486007B2 (en) | 2014-06-04 | 2022-11-01 | Quest Diagnostics Investments Incorporated | Methylated markers for colorectal cancer |
| AU2015271641B2 (en) | 2014-06-05 | 2021-04-08 | Clinical Genomics Pty Ltd | Method for methylation analysis |
| US10480021B2 (en) | 2014-06-23 | 2019-11-19 | Yale University | Methods for closed chromatin mapping and DNA methylation analysis for single cells |
| EP3760739A1 (en) | 2014-07-30 | 2021-01-06 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| SG11201705615UA (en) * | 2015-01-12 | 2017-08-30 | 10X Genomics Inc | Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same |
| US9984201B2 (en) | 2015-01-18 | 2018-05-29 | Youhealth Biotech, Limited | Method and system for determining cancer status |
| US10883138B2 (en) | 2015-04-23 | 2021-01-05 | Quest Diagnostics Investments Incorporated | MLH1 methylation assay |
| US20170101674A1 (en) * | 2015-08-21 | 2017-04-13 | Toma Biosciences, Inc. | Methods, compositions, and kits for nucleic acid analysis |
| GB201515557D0 (en) | 2015-09-02 | 2015-10-14 | 14M Genomics Ltd | Method of sequencing |
| EP3168309B8 (en) | 2015-11-10 | 2020-06-03 | Eurofins LifeCodexx GmbH | Detection of foetal chromosomal aneuploidies using dna regions that are differentially methylated between the foetus and the pregnant female |
| KR102006803B1 (ko) | 2016-10-06 | 2019-08-05 | (주)지노믹트리 | 메틸화 dna 다중 검출방법 |
| CN110785490A (zh) | 2017-04-19 | 2020-02-11 | 鹍远基因公司 | 用于检测基因组变异和dna甲基化状态的组合物和方法 |
-
2018
- 2018-04-18 CN CN201880040459.0A patent/CN110770354B/zh active Active
- 2018-04-18 SG SG10202111266VA patent/SG10202111266VA/en unknown
- 2018-04-18 CA CA3060555A patent/CA3060555A1/en active Pending
- 2018-04-18 EP EP18788271.7A patent/EP3612641A4/en active Pending
- 2018-04-18 US US16/605,203 patent/US11965157B2/en active Active
- 2018-04-18 JP JP2020507488A patent/JP7220200B2/ja active Active
- 2018-04-18 SG SG11201909618T patent/SG11201909618TA/en unknown
- 2018-04-18 AU AU2018256387A patent/AU2018256387A1/en active Pending
- 2018-04-18 WO PCT/US2018/028191 patent/WO2018195217A1/en unknown
- 2018-04-18 KR KR1020197033449A patent/KR102601593B1/ko active IP Right Grant
- 2018-04-19 TW TW107113306A patent/TWI797118B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018256387A1 (en) | 2019-10-31 |
| TW201842189A (zh) | 2018-12-01 |
| TWI797118B (zh) | 2023-04-01 |
| SG10202111266VA (en) | 2021-11-29 |
| CN110770354A (zh) | 2020-02-07 |
| US11965157B2 (en) | 2024-04-23 |
| KR20190140961A (ko) | 2019-12-20 |
| CN110770354B (zh) | 2024-03-19 |
| JP2020517298A (ja) | 2020-06-18 |
| JP7220200B2 (ja) | 2023-02-09 |
| KR102601593B1 (ko) | 2023-11-13 |
| EP3612641A4 (en) | 2021-01-20 |
| CA3060555A1 (en) | 2018-10-25 |
| US20200123538A1 (en) | 2020-04-23 |
| WO2018195217A1 (en) | 2018-10-25 |
| EP3612641A1 (en) | 2020-02-26 |
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