SG11201908531WA - Combination therapies for the treatment of breast cancer - Google Patents
Combination therapies for the treatment of breast cancerInfo
- Publication number
- SG11201908531WA SG11201908531WA SG11201908531WA SG11201908531WA SG 11201908531W A SG11201908531W A SG 11201908531WA SG 11201908531W A SG11201908531W A SG 11201908531WA SG 11201908531W A SG11201908531W A SG 11201908531WA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- massachusetts
- rule
- pct
- applicant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762472345P | 2017-03-16 | 2017-03-16 | |
| PCT/US2018/022961 WO2018170447A1 (fr) | 2017-03-16 | 2018-03-16 | Polythérapies pour le traitement du cancer du sein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201908531WA true SG11201908531WA (en) | 2019-10-30 |
Family
ID=61874039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201908531W SG11201908531WA (en) | 2017-03-16 | 2018-03-16 | Combination therapies for the treatment of breast cancer |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11083722B2 (fr) |
| EP (2) | EP4218820A3 (fr) |
| JP (1) | JP7219224B2 (fr) |
| KR (1) | KR102517650B1 (fr) |
| CN (1) | CN110636862A (fr) |
| AU (1) | AU2018234903B2 (fr) |
| BR (1) | BR112019019261A2 (fr) |
| CA (1) | CA3056701A1 (fr) |
| IL (1) | IL269357A (fr) |
| MA (1) | MA47776A (fr) |
| MX (1) | MX2019010981A (fr) |
| RU (1) | RU2764724C2 (fr) |
| SG (1) | SG11201908531WA (fr) |
| WO (1) | WO2018170447A1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102425785B1 (ko) * | 2016-11-28 | 2022-07-28 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 인다졸 유도체의 염 및 이의 결정 |
| RU2020123665A (ru) | 2018-01-08 | 2022-02-10 | Г1 Терапьютикс, Инк. | Преимущественные режимы дозирования g1т38 |
| KR20230104158A (ko) * | 2020-11-06 | 2023-07-07 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 유방암의 치료 방법 |
| CN113018357A (zh) * | 2021-02-08 | 2021-06-25 | 湖南农业大学 | 茶多酚和帕博西尼联合在制备治疗乳腺癌的制剂中的用途 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6399633B1 (en) | 1999-02-01 | 2002-06-04 | Aventis Pharmaceuticals Inc. | Use of 4-H-1-benzopryan-4-one derivatives as inhibitors of smooth muscle cell proliferation |
| DE19959546A1 (de) | 1999-12-09 | 2001-06-21 | Rhone Poulenc Rorer Gmbh | Pharmazeutische Zubereitung zur Behandlung von Tumorerkrankungen |
| WO2001053293A1 (fr) | 2000-01-18 | 2001-07-26 | Aventis Pharmaceuticals Inc. | Pseudopolymorphe d'hydrochlorure (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one |
| PT1252155E (pt) | 2000-01-18 | 2005-04-29 | Aventis Pharma Inc | Solvato de etanol de (-)-cis-2-(2-clorofenil)-5,7-di-hidroxi-8-[4r-(3s-hidroxi-1-metil)piperidinil]-4h-1-bezopiran-4-ona |
| AU2001287157A1 (en) | 2000-09-12 | 2002-03-26 | Virginia Commonwealth University | Promotion of adoptosis in cancer cells by co-administration of cyclin dependent kinase inhibitors and cellular differentiation agents |
| ATE314370T1 (de) | 2002-01-22 | 2006-01-15 | Warner Lambert Co | 2-(pyridin-2-ylamino)-pyrido(2,3-d)pyrimidin-7- one |
| PL2256106T3 (pl) | 2003-07-22 | 2015-08-31 | Astex Therapeutics Ltd | Związki 3,4-pochodne 1h-pirazolu i ich zastosowanie jako kinazy zależne od cyklin (cdk) i modulatory kinazy syntazy glikogenu-3 (gsk-3) |
| JP5475235B2 (ja) | 2005-01-21 | 2014-04-16 | アステックス・セラピューティクス・リミテッド | 医薬化合物 |
| KR101345002B1 (ko) | 2005-01-21 | 2013-12-31 | 아스텍스 테라퓨틱스 리미티드 | 제약 화합물 |
| US20080161355A1 (en) | 2005-01-21 | 2008-07-03 | Astex Therapeutics Limited | Combinations of Pyrazole Kinase Inhibitors and Further Antitumor Agents |
| AR054425A1 (es) | 2005-01-21 | 2007-06-27 | Astex Therapeutics Ltd | Sales de adicion de piperidin 4-il- amida de acido 4-(2,6-dicloro-benzoilamino) 1h-pirazol-3-carboxilico. |
| JP2008255008A (ja) | 2005-07-19 | 2008-10-23 | Tokyo Medical & Dental Univ | 滑膜細胞増殖抑制剤 |
| US7776832B2 (en) * | 2006-04-21 | 2010-08-17 | Gem Pharmaceuticals, Llc | Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclines |
| TWI398252B (zh) | 2006-05-26 | 2013-06-11 | Novartis Ag | 吡咯并嘧啶化合物及其用途 |
| US20110159111A1 (en) | 2006-06-29 | 2011-06-30 | Astex Therapeutics Limited | Pharmaceutical combinations |
| US20090263398A1 (en) | 2006-07-14 | 2009-10-22 | Astex Therapeutics Limited | Pharmaceutical combinations |
| US20100021420A1 (en) | 2006-07-14 | 2010-01-28 | Astex Therapeutics Limited | Combinations of pyrazole derivatives for the inhibition of cdks and gsk's |
| JP2009544602A (ja) | 2006-07-21 | 2009-12-17 | アステックス・セラピューティクス・リミテッド | サイクリン依存性キナーゼ阻害剤の医学的使用 |
| US7902147B2 (en) | 2007-11-05 | 2011-03-08 | Duke University | Chronic lymphocytic leukemia prognosis and treatment |
| PL2331547T3 (pl) | 2008-08-22 | 2015-01-30 | Novartis Ag | Związki pirolopirymidynowe jako inhibitory CDK |
| PA8852901A1 (es) | 2008-12-22 | 2010-07-27 | Lilly Co Eli | Inhibidores de proteina cinasa |
| UY33226A (es) | 2010-02-19 | 2011-09-30 | Novartis Ag | Compuestos de pirrolopirimidina deuterada como inhibidores de la cdk4/6 |
| MX2012011912A (es) | 2010-04-13 | 2012-11-16 | Novartis Ag | Combinacion que comprende un inhibidor de cinasa 4 dependiente de ciclina o cinasa dependiente de ciclia (cdk4/6) y un inhibidor de mtor para tratar cancer. |
| GB2483736B (en) | 2010-09-16 | 2012-08-29 | Aragon Pharmaceuticals Inc | Estrogen receptor modulators and uses thereof |
| JP5923509B2 (ja) | 2010-10-25 | 2016-05-24 | ジー１、セラピューティクス、インコーポレイテッドＧ１ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | Ｃｄｋ阻害剤 |
| US20120115878A1 (en) | 2010-11-10 | 2012-05-10 | John Vincent Calienni | Salt(s) of 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7h-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide and processes of making thereof |
| KR20160035613A (ko) | 2011-03-23 | 2016-03-31 | 암젠 인크 | Cdk 4/6 및 flt3의 융합된 트리사이클릭 이중 저해제 |
| JP2016501221A (ja) | 2012-11-28 | 2016-01-18 | ノバルティス アーゲー | 併用療法 |
| US9527857B2 (en) | 2013-03-15 | 2016-12-27 | GI Therapeutics, Inc. | HSPC-sparing treatments for RB-positive abnormal cellular proliferation |
| PT3033086T (pt) | 2013-08-14 | 2021-12-15 | Novartis Ag | Terapia de combinação para o tratamento de cancro |
| WO2015136016A2 (fr) | 2014-03-13 | 2015-09-17 | F. Hoffmann-La Roche Ag | Combinaisons thérapeutiques avec des modulateurs du récepteur des œstrogènes |
| WO2016025650A1 (fr) | 2014-08-13 | 2016-02-18 | Celgene Avilomics Research, Inc. | Combinaisons d'un inhibiteur de erk et d'un inhibiteur cdk4/6 et méthodes associées |
| WO2016040848A1 (fr) | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Traitement de tumeurs rb-négatives en utilisant des inhibiteurs de la topoisomérase en association avec des inhibiteurs des kinases cycline-dépendantes 4/6 |
| CN104529904B (zh) | 2015-01-09 | 2016-08-31 | 苏州明锐医药科技有限公司 | 玻玛西尼的制备方法 |
| WO2016126889A1 (fr) | 2015-02-03 | 2016-08-11 | G1 Therapeutics, Inc. | Formulations posologiques d'inhibiteur de cdk4/6 destinées à protéger les cellules souches et progénitrices hématopoïetiques lors d'une chimiothérapie |
| IL307981A (en) * | 2015-04-29 | 2023-12-01 | Radius Pharmaceuticals Inc | Cancer treatment methods |
| IL255765B2 (en) * | 2015-05-29 | 2023-10-01 | Eisai R&D Man Co Ltd | 5-{[(1-(PHENYL/PYRIDYL)-2-PHENYL]-ETHEN-1-YL}-INDAZOLE compounds and their use |
-
2018
- 2018-03-16 JP JP2019550800A patent/JP7219224B2/ja active Active
- 2018-03-16 WO PCT/US2018/022961 patent/WO2018170447A1/fr unknown
- 2018-03-16 MX MX2019010981A patent/MX2019010981A/es unknown
- 2018-03-16 MA MA047776A patent/MA47776A/fr unknown
- 2018-03-16 BR BR112019019261-1A patent/BR112019019261A2/pt unknown
- 2018-03-16 KR KR1020197029851A patent/KR102517650B1/ko active IP Right Grant
- 2018-03-16 SG SG11201908531W patent/SG11201908531WA/en unknown
- 2018-03-16 EP EP23159590.1A patent/EP4218820A3/fr active Pending
- 2018-03-16 CN CN201880030008.9A patent/CN110636862A/zh active Pending
- 2018-03-16 AU AU2018234903A patent/AU2018234903B2/en active Active
- 2018-03-16 US US16/493,931 patent/US11083722B2/en active Active
- 2018-03-16 EP EP18715441.4A patent/EP3595725B1/fr active Active
- 2018-03-16 RU RU2019132893A patent/RU2764724C2/ru active
- 2018-03-16 CA CA3056701A patent/CA3056701A1/fr active Pending
-
2019
- 2019-09-15 IL IL26935719A patent/IL269357A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3595725B1 (fr) | 2023-05-03 |
| MX2019010981A (es) | 2020-09-07 |
| CN110636862A (zh) | 2019-12-31 |
| JP7219224B2 (ja) | 2023-02-07 |
| WO2018170447A1 (fr) | 2018-09-20 |
| RU2019132893A3 (fr) | 2021-06-24 |
| US20210113537A1 (en) | 2021-04-22 |
| IL269357A (en) | 2019-11-28 |
| MA47776A (fr) | 2020-01-22 |
| BR112019019261A2 (pt) | 2020-06-16 |
| KR20190125448A (ko) | 2019-11-06 |
| EP4218820A3 (fr) | 2023-09-20 |
| KR102517650B1 (ko) | 2023-04-05 |
| RU2019132893A (ru) | 2021-04-16 |
| EP4218820A2 (fr) | 2023-08-02 |
| AU2018234903B2 (en) | 2024-02-08 |
| AU2018234903A1 (en) | 2019-10-10 |
| US11083722B2 (en) | 2021-08-10 |
| EP3595725A1 (fr) | 2020-01-22 |
| CA3056701A1 (fr) | 2018-09-20 |
| JP2020510075A (ja) | 2020-04-02 |
| RU2764724C2 (ru) | 2022-01-19 |
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