SG11201907935XA - 2,6-disubstituted pyridine derivative - Google Patents

2,6-disubstituted pyridine derivative

Info

Publication number
SG11201907935XA
SG11201907935XA SG11201907935XA SG11201907935XA SG11201907935XA SG 11201907935X A SG11201907935X A SG 11201907935XA SG 11201907935X A SG11201907935X A SG 11201907935XA SG 11201907935X A SG11201907935X A SG 11201907935XA SG 11201907935X A SG11201907935X A SG 11201907935XA
Authority
SG
Singapore
Prior art keywords
substituted
optionally
alkyl
same
pyridine derivative
Prior art date
Application number
SG11201907935XA
Other languages
English (en)
Inventor
Hidefumi Yoshinaga
Hiro Uemachi
Tomomi Ohno
Jeremy Besnard
Original Assignee
Sumitomo Dainippon Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Dainippon Pharma Co Ltd filed Critical Sumitomo Dainippon Pharma Co Ltd
Publication of SG11201907935XA publication Critical patent/SG11201907935XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11201907935XA 2017-03-13 2018-03-12 2,6-disubstituted pyridine derivative SG11201907935XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017046904 2017-03-13
PCT/JP2018/009418 WO2018168738A1 (ja) 2017-03-13 2018-03-12 2,6-ジ置換ピリジン誘導体

Publications (1)

Publication Number Publication Date
SG11201907935XA true SG11201907935XA (en) 2019-09-27

Family

ID=63522157

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201907935XA SG11201907935XA (en) 2017-03-13 2018-03-12 2,6-disubstituted pyridine derivative

Country Status (11)

Country Link
US (4) US11014905B2 (de)
EP (1) EP3608314A4 (de)
JP (2) JP6612483B2 (de)
KR (1) KR20190129080A (de)
CN (1) CN110382478A (de)
AU (1) AU2018234001B2 (de)
CA (1) CA3054782A1 (de)
RU (1) RU2019132041A (de)
SG (1) SG11201907935XA (de)
TW (1) TW201837034A (de)
WO (1) WO2018168738A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110382478A (zh) 2017-03-13 2019-10-25 大日本住友制药株式会社 2,6-二取代的吡啶衍生物
JP7382188B2 (ja) * 2018-09-19 2023-11-16 住友ファーマ株式会社 2,6-ジ置換ピリジン誘導体からなる医薬

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5929665A (ja) 1982-08-11 1984-02-16 Sumitomo Chem Co Ltd ピペラジン誘導体及びその酸付加塩
CA1305148C (en) * 1987-08-19 1992-07-14 Hiromu Matsumura Carbamoylpyrrolidone derivatives and drugs for senile dementia
JPH075546B2 (ja) * 1987-08-19 1995-01-25 塩野義製薬株式会社 カルバモイルピロリドン誘導体
CA2100641A1 (en) 1992-07-23 1994-01-24 Hiromu Matsumura Novel piperidine derivatives and process for preparation thereof
JP4866610B2 (ja) * 2003-08-18 2012-02-01 富士フイルムファインケミカルズ株式会社 ピリジルテトラヒドロピリジン類およびピリジルピペリジン類
EP1836192A2 (de) * 2005-01-03 2007-09-26 Universita' Degli Studi di Siena Arylpiperazin-derivate zur behandlung neuropsychiatrischer erkrankungen
JP2009249346A (ja) * 2008-04-08 2009-10-29 Fujifilm Corp ピリジン骨格を有する血液脳関門透過性化合物
EP2571353B1 (de) 2010-05-21 2017-08-09 AbbVie Inc. 5-ht-rezeptor-modulatoren und verfahren zu ihrer verwendung
WO2011150183A1 (en) * 2010-05-28 2011-12-01 Ge Healthcare Limited Radiolabeled compounds and methods thereof
JP5929665B2 (ja) 2012-09-24 2016-06-08 富士通株式会社 電解コンデンサとその製造方法
JP2014192868A (ja) 2013-03-28 2014-10-06 Fujitsu Ltd 端末装置、消費電力抑制方法及び消費電力抑制プログラム
JP6370294B2 (ja) 2013-05-30 2018-08-08 大日本住友製薬株式会社 環状アミノメチルピリミジン誘導体
CN110382478A (zh) 2017-03-13 2019-10-25 大日本住友制药株式会社 2,6-二取代的吡啶衍生物

Also Published As

Publication number Publication date
US20200039952A1 (en) 2020-02-06
US11014905B2 (en) 2021-05-25
RU2019132041A (ru) 2021-04-14
RU2019132041A3 (de) 2021-07-05
US11780820B2 (en) 2023-10-10
JP7097342B2 (ja) 2022-07-07
AU2018234001B2 (en) 2022-01-06
US10800755B2 (en) 2020-10-13
WO2018168738A8 (ja) 2019-07-25
KR20190129080A (ko) 2019-11-19
WO2018168738A1 (ja) 2018-09-20
EP3608314A4 (de) 2020-12-30
JP6612483B2 (ja) 2019-11-27
CN110382478A (zh) 2019-10-25
CA3054782A1 (en) 2018-09-20
US20200239432A1 (en) 2020-07-30
US20230399308A1 (en) 2023-12-14
AU2018234001A1 (en) 2019-09-19
JP2020023570A (ja) 2020-02-13
TW201837034A (zh) 2018-10-16
JPWO2018168738A1 (ja) 2019-11-21
EP3608314A1 (de) 2020-02-12
US20210332025A1 (en) 2021-10-28

Similar Documents

Publication Publication Date Title
PH12020500485A1 (en) Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors
MX2018000396A (es) Compuestos aza sustituidos como inhibidores de cinasa 4 asociada al receptor de interleucina 1 (irak-4).
PH12016502382A1 (en) Substituted indazole compounds as irak4 inhibitors
PE20161475A1 (es) Pirazolopiridinas y pirazolopirimidinas
MX2017010477A (es) Compuestos triciclicos y usos de los mismos en medicina.
MD4800C1 (ro) Compuşi de aminopirimidinil ca inhibitori de JAK
GEP20207105B (en) 1,1,1-trifluoro-3-hydroxypropan-2-yl carbamate derivatives and 1,1,1-trifluoro-4-hydroxybutan-2yl carbamate derivatives as magl inhibitors
EA201890469A1 (ru) Соли ингибитора lsd1
PH12019500480A1 (en) Pyridine compound
WO2015095811A8 (en) Combination therapy with neoantigen vaccine
BR112015012693A2 (pt) derivados de pirimidona e seu uso no tratamento, melhora ou prevenção de uma doença viral
EA201591745A1 (ru) 3-пиримидин-4-ил-оксазолидин-2-оны в качестве ингибиторов мутантого idh
BR112015018509A2 (pt) compostos de imidazo piridina
MX2015012741A (es) Palbociclib deuterado.
NZ748769A (en) Nitroxyl donors with improved therapeutic index
PH12018501443A1 (en) Methods of administering hepcidin
BR112015016184A2 (pt) derivados de piridona e seu uso no tratamento, melhora ou prevenção de uma doença viral
SA519401322B1 (ar) مركبات أريل كربوكساميد غير متجانسة كمثطبات لكيناز بروتين سيرين/ ثريونين متداخل مع المستقبل 2
BR112012031340A2 (pt) derivados de cianoquinolina
MX2016016491A (es) Derivados de o-alquil-bencilidenguanidina y uso terapeutico para el tratamiento de trastornos asociados con acumulacion de proteinas mal plegadas.
MX2016004963A (es) Sal y formas cristalinas de inhibidores de quinasa tipo polo-4.
SG11201907935XA (en) 2,6-disubstituted pyridine derivative
WO2015155680A3 (en) Pyrazole derivatives as dihydroorotate dehydrogenase (dhodh) inhibitors
BR112015013414A2 (pt) derivados de naftiridona e seu uso no tratamento, melhora ou prevenção de uma doença viral
RU2016133022A (ru) Средство для профилактики и/или терапии ретинального воспаления