SG11201907030VA - Method for controlling differentiation of pluripotent stem cells - Google Patents

Method for controlling differentiation of pluripotent stem cells

Info

Publication number
SG11201907030VA
SG11201907030VA SG11201907030VA SG11201907030VA SG11201907030VA SG 11201907030V A SG11201907030V A SG 11201907030VA SG 11201907030V A SG11201907030V A SG 11201907030VA SG 11201907030V A SG11201907030V A SG 11201907030VA SG 11201907030V A SG11201907030V A SG 11201907030VA
Authority
SG
Singapore
Prior art keywords
pluripotent stem
stem cells
cells
controlling differentiation
laminin
Prior art date
Application number
SG11201907030VA
Other languages
English (en)
Inventor
Kohji Nishida
Kiyotoshi Sekiguchi
Ryuhei Hayashi
Shun Shibata
Original Assignee
Univ Osaka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Osaka filed Critical Univ Osaka
Publication of SG11201907030VA publication Critical patent/SG11201907030VA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0619Neurons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0621Eye cells, e.g. cornea, iris pigmented cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998Proteins not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/52Fibronectin; Laminin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
SG11201907030VA 2017-01-31 2018-01-31 Method for controlling differentiation of pluripotent stem cells SG11201907030VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017016302 2017-01-31
PCT/JP2018/003315 WO2018143312A1 (ja) 2017-01-31 2018-01-31 多能性幹細胞の分化制御方法

Publications (1)

Publication Number Publication Date
SG11201907030VA true SG11201907030VA (en) 2019-08-27

Family

ID=63039756

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201907030VA SG11201907030VA (en) 2017-01-31 2018-01-31 Method for controlling differentiation of pluripotent stem cells

Country Status (10)

Country Link
US (1) US11649433B2 (ko)
EP (1) EP3578640A4 (ko)
JP (1) JP6942363B2 (ko)
KR (1) KR102208889B1 (ko)
CN (1) CN110234755B (ko)
AU (1) AU2018215170B2 (ko)
CA (1) CA3052124A1 (ko)
MY (1) MY192056A (ko)
SG (1) SG11201907030VA (ko)
WO (1) WO2018143312A1 (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220008894A (ko) * 2019-05-15 2022-01-21 아지노모토 가부시키가이샤 신경제세포 또는 각막 상피 세포의 순화 방법
JP7285520B2 (ja) * 2019-08-06 2023-06-02 花王株式会社 皮膚由来多能性前駆細胞の作製方法
CN112458039A (zh) * 2020-12-04 2021-03-09 浙江大学 一种肺泡类器官增殖和分化用的培养基及方法
CN116970566B (zh) * 2023-09-22 2024-01-09 北京大学口腔医学院 诱导间充质干细胞神经分化的方法、神经干细胞及用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6361996B1 (en) 1997-05-07 2002-03-26 University Of Utah Research Foundation Neuroepithelial stem cells and glial-restricted intermediate precursors
US6703363B1 (en) * 1999-04-30 2004-03-09 Biostratum, Inc. Recombinant laminin 5
AU2003228255A1 (en) 2002-05-28 2003-12-19 Becton, Dickinson And Company Pancreatic acinar cells into insulin-producing cells
MX347303B (es) * 2006-03-07 2017-04-21 Shroff Geeta Composiciones que comprenden celulas madre embrionarias humanas y sus derivados, metodos de uso y metodos de preparacion.
AU2006346492A1 (en) * 2006-07-24 2008-01-31 International Stem Cell Corporation Synthetic cornea from retinal stem cells
US20120142103A1 (en) 2009-05-18 2012-06-07 Kohji Nishida Method for inducing differentiation into epithelial progenitor cell/stem cell population and corneal epithelial cell population from induced pluripotent stem cells
JP5590646B2 (ja) * 2009-10-08 2014-09-17 国立大学法人大阪大学 ヒト多能性幹細胞用培養基材およびその利用
US9598281B2 (en) 2011-03-03 2017-03-21 The Regents Of The University Of California Nanopipette apparatus for manipulating cells
EP2700709A4 (en) * 2011-04-20 2014-11-19 Univ Osaka IPS CELL HAVING PREDISPOSITION FOR CORNEAL EPITHELIUM DIFFERENTIATION
CN105189738A (zh) 2013-04-08 2015-12-23 国立研究开发法人医药基盘·健康·营养研究所 肝母细胞样细胞的培养方法及其培养物
WO2014199754A1 (ja) * 2013-06-12 2014-12-18 国立大学法人大阪大学 ラミニンフラグメントが乾燥状態でコーティングされている細胞培養器具
WO2015068505A1 (ja) 2013-11-11 2015-05-14 住友化学株式会社 網膜色素上皮細胞の製造方法
BR112016011096A2 (pt) 2013-11-27 2017-09-19 Kyoto Prefectural Public Univ Corp Aplicação de laminina à cultura de célula endotelial da córnea
WO2016114285A1 (ja) * 2015-01-15 2016-07-21 国立大学法人大阪大学 多能性幹細胞からの角膜上皮細胞の分化誘導
CN106167790B (zh) * 2016-06-22 2019-11-19 中国人民解放军总医院 人胚胎干细胞定向诱导分化为角膜内皮细胞的方法

Also Published As

Publication number Publication date
JPWO2018143312A1 (ja) 2019-12-12
WO2018143312A1 (ja) 2018-08-09
JP6942363B2 (ja) 2021-09-29
US11649433B2 (en) 2023-05-16
CN110234755A (zh) 2019-09-13
US20200010800A1 (en) 2020-01-09
AU2018215170A1 (en) 2019-09-12
KR102208889B1 (ko) 2021-01-27
EP3578640A4 (en) 2020-06-10
MY192056A (en) 2022-07-25
EP3578640A1 (en) 2019-12-11
AU2018215170B2 (en) 2021-11-11
CN110234755B (zh) 2023-08-29
KR20190112090A (ko) 2019-10-02
CA3052124A1 (en) 2018-08-09

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