SG11201900096QA - Novel processes for preparation of soluble guanylate cyclase stimulators - Google Patents
Novel processes for preparation of soluble guanylate cyclase stimulatorsInfo
- Publication number
- SG11201900096QA SG11201900096QA SG11201900096QA SG11201900096QA SG11201900096QA SG 11201900096Q A SG11201900096Q A SG 11201900096QA SG 11201900096Q A SG11201900096Q A SG 11201900096QA SG 11201900096Q A SG11201900096Q A SG 11201900096QA SG 11201900096Q A SG11201900096Q A SG 11201900096QA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- preparation
- massachusetts
- pct
- guanylate cyclase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Enzymes And Modification Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662359453P | 2016-07-07 | 2016-07-07 | |
| PCT/US2017/040810 WO2018009597A1 (en) | 2016-07-07 | 2017-07-06 | Novel processes for preparation of soluble guanylate cyclase stimulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201900096QA true SG11201900096QA (en) | 2019-02-27 |
Family
ID=59416789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201900096QA SG11201900096QA (en) | 2016-07-07 | 2017-07-06 | Novel processes for preparation of soluble guanylate cyclase stimulators |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US11319308B2 (https=) |
| EP (2) | EP4249488A3 (https=) |
| JP (1) | JP7112384B2 (https=) |
| KR (1) | KR102487872B1 (https=) |
| CN (2) | CN109563077B (https=) |
| AU (1) | AU2017291827B2 (https=) |
| BR (1) | BR112019000291A2 (https=) |
| CA (1) | CA3029375A1 (https=) |
| CL (2) | CL2019000016A1 (https=) |
| EA (1) | EA201990237A1 (https=) |
| ES (1) | ES2963563T3 (https=) |
| IL (1) | IL263995B (https=) |
| MA (1) | MA45603A (https=) |
| MX (2) | MX389920B (https=) |
| SG (1) | SG11201900096QA (https=) |
| WO (1) | WO2018009597A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109563086B (zh) | 2016-07-07 | 2023-05-23 | 赛克里翁治疗有限公司 | 用于制备可溶性鸟苷酸环化酶刺激剂的方法 |
| CN109563077B (zh) | 2016-07-07 | 2026-03-10 | 赛克里翁治疗有限公司 | 用于制备可溶性鸟苷酸环化酶刺激剂的新方法 |
| US11274096B2 (en) | 2018-01-10 | 2022-03-15 | Cyclerion Therapeutics, Inc. | Processes and intermediates for the preparation of soluble guanylate cyclase stimulators |
| WO2019161534A1 (en) * | 2018-02-22 | 2019-08-29 | Ironwood Pharmaceuticals, Inc. | Novel processes and intermediates for preparation of soluble guanylate cyclase stimulators |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8969349B2 (en) * | 2010-05-26 | 2015-03-03 | Sunovion Pharmaceuticals Inc. | Substituted quinoxalines and quinoxalinones as PDE-10 inhibitors |
| EP2588465B1 (en) | 2010-06-30 | 2017-01-25 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| CN106117194A (zh) * | 2011-12-27 | 2016-11-16 | 铁木医药有限公司 | 可用作sgc刺激剂的2‑苄基、3‑(嘧啶‑2‑基)取代的吡唑类 |
| EP2897953B8 (en) * | 2012-09-19 | 2019-06-26 | Cyclerion Therapeutics, Inc. | Sgc stimulators |
| EA033168B1 (ru) | 2013-03-15 | 2019-09-30 | Сайклерион Терапьютикс, Инк. | СТИМУЛЯТОРЫ sGC |
| CA2933250A1 (en) | 2013-12-11 | 2015-06-18 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| EP3194386A2 (en) * | 2014-09-17 | 2017-07-26 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| EP3194382B1 (en) * | 2014-09-17 | 2021-09-08 | Cyclerion Therapeutics, Inc. | Pyrazole derivatives as sgc stimulators |
| EA201790627A1 (ru) * | 2014-09-17 | 2017-09-29 | Айронвуд Фармасьютикалз, Инк. | СТИМУЛЯТОРЫ рГЦ |
| US20170298055A1 (en) * | 2014-09-17 | 2017-10-19 | Ironwood Pharmaceuticals, Inc. | sGC STIMULATORS |
| CA3006746C (en) * | 2015-11-30 | 2024-01-30 | Ironwood Pharmaceuticals, Inc. | Solid dispersions comprising a sgc stimulator |
| CN109563086B (zh) * | 2016-07-07 | 2023-05-23 | 赛克里翁治疗有限公司 | 用于制备可溶性鸟苷酸环化酶刺激剂的方法 |
| CN109563087A (zh) | 2016-07-07 | 2019-04-02 | 铁木医药有限公司 | sGC刺激剂的固体形式 |
| CN109563077B (zh) | 2016-07-07 | 2026-03-10 | 赛克里翁治疗有限公司 | 用于制备可溶性鸟苷酸环化酶刺激剂的新方法 |
| MX2020006433A (es) * | 2017-12-19 | 2020-09-17 | Cyclerion Therapeutics Inc | Estimuladores de guanilato ciclasa soluble (sgc). |
| US11274096B2 (en) * | 2018-01-10 | 2022-03-15 | Cyclerion Therapeutics, Inc. | Processes and intermediates for the preparation of soluble guanylate cyclase stimulators |
-
2017
- 2017-07-06 CN CN201780047020.6A patent/CN109563077B/zh active Active
- 2017-07-06 JP JP2019500355A patent/JP7112384B2/ja active Active
- 2017-07-06 WO PCT/US2017/040810 patent/WO2018009597A1/en not_active Ceased
- 2017-07-06 AU AU2017291827A patent/AU2017291827B2/en active Active
- 2017-07-06 CA CA3029375A patent/CA3029375A1/en active Pending
- 2017-07-06 KR KR1020197003459A patent/KR102487872B1/ko active Active
- 2017-07-06 MA MA045603A patent/MA45603A/fr unknown
- 2017-07-06 ES ES17745553T patent/ES2963563T3/es active Active
- 2017-07-06 EP EP23185002.5A patent/EP4249488A3/en active Pending
- 2017-07-06 EA EA201990237A patent/EA201990237A1/ru unknown
- 2017-07-06 EP EP17745553.2A patent/EP3481818B1/en active Active
- 2017-07-06 MX MX2019000105A patent/MX389920B/es unknown
- 2017-07-06 US US16/315,218 patent/US11319308B2/en active Active
- 2017-07-06 SG SG11201900096QA patent/SG11201900096QA/en unknown
- 2017-07-06 CN CN202511803316.9A patent/CN121673266A/zh active Pending
- 2017-07-06 BR BR112019000291A patent/BR112019000291A2/pt not_active Application Discontinuation
-
2018
- 2018-12-27 IL IL263995A patent/IL263995B/en active IP Right Grant
-
2019
- 2019-01-04 CL CL2019000016A patent/CL2019000016A1/es unknown
- 2019-01-07 MX MX2022001495A patent/MX2022001495A/es unknown
-
2022
- 2022-03-30 US US17/708,296 patent/US11773089B2/en active Active
-
2023
- 2023-01-24 CL CL2023000228A patent/CL2023000228A1/es unknown
- 2023-08-24 US US18/237,435 patent/US20240059684A1/en not_active Abandoned
-
2025
- 2025-04-23 US US19/187,279 patent/US20260103457A1/en active Pending
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