SG11201809594WA - Nicotine particles and compositions - Google Patents

Nicotine particles and compositions

Info

Publication number
SG11201809594WA
SG11201809594WA SG11201809594WA SG11201809594WA SG11201809594WA SG 11201809594W A SG11201809594W A SG 11201809594WA SG 11201809594W A SG11201809594W A SG 11201809594WA SG 11201809594W A SG11201809594W A SG 11201809594WA SG 11201809594W A SG11201809594W A SG 11201809594WA
Authority
SG
Singapore
Prior art keywords
international
pct
particles
english
june
Prior art date
Application number
SG11201809594WA
Other languages
English (en)
Inventor
Gerard Zuber
Nicolo Volpe
Original Assignee
Philip Morris Products Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products Sa filed Critical Philip Morris Products Sa
Publication of SG11201809594WA publication Critical patent/SG11201809594WA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Addiction (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
SG11201809594WA 2016-06-30 2017-06-14 Nicotine particles and compositions SG11201809594WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16177163 2016-06-30
PCT/IB2017/053543 WO2018002756A1 (fr) 2016-06-30 2017-06-14 Les particules de nicotine.

Publications (1)

Publication Number Publication Date
SG11201809594WA true SG11201809594WA (en) 2018-11-29

Family

ID=56296661

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201809594WA SG11201809594WA (en) 2016-06-30 2017-06-14 Nicotine particles and compositions

Country Status (18)

Country Link
US (2) US20190133940A1 (fr)
EP (1) EP3478264A1 (fr)
JP (2) JP2019524648A (fr)
KR (1) KR102523677B1 (fr)
CN (1) CN109310622A (fr)
AR (1) AR108920A1 (fr)
AU (1) AU2017286864A1 (fr)
BR (1) BR112018076215A2 (fr)
CA (1) CA3023630A1 (fr)
IL (1) IL263355A (fr)
MX (1) MX2018015118A (fr)
PH (1) PH12018502714A1 (fr)
RU (2) RU2021132299A (fr)
SG (1) SG11201809594WA (fr)
TW (1) TW201801716A (fr)
UA (1) UA124535C2 (fr)
WO (1) WO2018002756A1 (fr)
ZA (1) ZA201806949B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190133940A1 (en) * 2016-06-30 2019-05-09 Philip Morris Products S.A. Nicotine particles and compositions
WO2020071448A1 (fr) * 2018-10-02 2020-04-09 学校法人名城大学 Inhalateur de poudre, méthode pour l'évaluer, et utilisation de celui-ci
EP4349182A2 (fr) * 2019-08-30 2024-04-10 Evie Sa Granules chargés de nicotine et leurs utilisations
CN110384700A (zh) * 2019-09-03 2019-10-29 云南喜科科技有限公司 一种合成尼古丁的组合物
ES2965397T3 (es) 2019-11-14 2024-04-15 Philip Morris Products Sa Formulación mejorada de polvo seco con sabor a tabaco
CN115135175A (zh) * 2019-12-19 2022-09-30 尤尔实验室有限公司 有机基尼古丁凝胶组合物
WO2021201258A1 (fr) * 2020-04-01 2021-10-07 株式会社ＳｔａｔｅＡｒｔ Composition contenant de l'acide nucléique, procédé de production d'une composition contenant de l'acide nucléique et procédé d'introduction d'acide nucléique
WO2022049487A1 (fr) * 2020-09-03 2022-03-10 Philip Morris Products S.A. Compositions de poudre active à faible hygroscopicité
MX2023002467A (es) * 2020-09-03 2023-03-23 Philip Morris Products Sa Composiciones en polvo activas de baja higroscopicidad secadas por atomizado.
WO2022049486A1 (fr) * 2020-09-03 2022-03-10 Philip Morris Products S.A. Compositions de poudres actives faiblement hygroscopiques lyophilisées

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2231968A1 (fr) * 1998-03-11 1999-09-11 Smoke-Stop, A Partnership Consisting Of Art Slutsky Methode de production d'un medicament a base de nicotine
US6586008B1 (en) * 1999-08-25 2003-07-01 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles during spray drying
JP2001151673A (ja) * 1999-09-06 2001-06-05 Nikken Chem Co Ltd 吸入用粉末製剤の製造方法
MXPA02004193A (es) * 1999-10-29 2002-12-13 Inhale Therapeutic Syst Composiciones de polvo seco que tienen caracteristicas de dispersion mejoradas.
SK11142002A3 (sk) * 1999-12-30 2004-09-08 Chiron Corporation Liečivo na podávanie interleukínu-2 a stabilizovaný lyofilizovaný alebo sprejovo sušený farmaceutický prostriedok s obsahom interleukínu-2
TWI283182B (en) * 2000-08-07 2007-07-01 Nektar Therapeutics Inhalable spray dried 4-helix bundle protein powders having minimized aggregation
US6962006B2 (en) * 2002-12-19 2005-11-08 Acusphere, Inc. Methods and apparatus for making particles using spray dryer and in-line jet mill
EP1802276A1 (fr) * 2004-10-15 2007-07-04 Pfizer Products Inc. Compositions et methodes d'administration par voie pulmonaire, sublinguale, orale et intranasale de varenicline
GB0425758D0 (en) * 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
ITMI20051999A1 (it) * 2005-10-21 2007-04-22 Eratech S R L Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita'
FI20060428L (fi) * 2006-05-03 2007-11-04 Esko Kauppinen Pintamodifioidut aerosolihiukkaset, menetelmä ja laite niiden tuottamiseksi sekä jauheet ja dispersiot jotka sisältävät kyseisiä hiukkasia
US20080286340A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
GB0801876D0 (en) * 2008-02-01 2008-03-12 Vectura Group Plc Suspension formulations
CA2944471C (fr) * 2014-04-08 2020-03-31 Sansa Corporation (Barbados) Inc. Formulations de nicotine et leurs procedes de preparation
KR102428028B1 (ko) * 2014-04-28 2022-08-03 필립모리스 프로덕츠 에스.에이. 향미를 가진 니코틴 분말 흡입기
US10149844B2 (en) * 2015-09-16 2018-12-11 Philip Morris Products S.A. Inhalable nicotine formulations, and methods of making and using thereof
US9585835B1 (en) * 2015-09-16 2017-03-07 Sansa Corporation (Barbados) Inc. Inhalable nicotine formulations and methods of making and using the same
US11224594B2 (en) * 2015-09-16 2022-01-18 Philip Morris Products S.A. Nicotine formulations and methods of making and using the same
UA126853C2 (uk) * 2016-06-30 2023-02-15 Філіп Морріс Продактс С.А. Нікотиновмісні частинки
US20190133940A1 (en) * 2016-06-30 2019-05-09 Philip Morris Products S.A. Nicotine particles and compositions
IL269275B2 (en) * 2017-06-28 2023-04-01 Philip Morris Products Sa Container with particles for use with an inhaler

Also Published As

Publication number Publication date
AU2017286864A1 (en) 2018-11-15
TW201801716A (zh) 2018-01-16
UA124535C2 (uk) 2021-10-05
CN109310622A (zh) 2019-02-05
PH12018502714A1 (en) 2019-07-29
BR112018076215A2 (pt) 2019-03-26
JP2019524648A (ja) 2019-09-05
RU2018145313A3 (fr) 2020-07-30
US20190133940A1 (en) 2019-05-09
AR108920A1 (es) 2018-10-10
RU2018145313A (ru) 2020-07-30
JP2022071106A (ja) 2022-05-13
KR20190025824A (ko) 2019-03-12
MX2018015118A (es) 2019-04-15
EP3478264A1 (fr) 2019-05-08
KR102523677B1 (ko) 2023-04-20
RU2021132299A (ru) 2021-12-10
ZA201806949B (en) 2019-07-31
WO2018002756A1 (fr) 2018-01-04
US20210361567A1 (en) 2021-11-25
CA3023630A1 (fr) 2018-01-04
RU2767064C2 (ru) 2022-03-16
IL263355A (en) 2018-12-31

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