SG11201809413RA - Detection of chromosome interaction relevant to breast cancer - Google Patents

Detection of chromosome interaction relevant to breast cancer

Info

Publication number
SG11201809413RA
SG11201809413RA SG11201809413RA SG11201809413RA SG11201809413RA SG 11201809413R A SG11201809413R A SG 11201809413RA SG 11201809413R A SG11201809413R A SG 11201809413RA SG 11201809413R A SG11201809413R A SG 11201809413RA SG 11201809413R A SG11201809413R A SG 11201809413RA
Authority
SG
Singapore
Prior art keywords
oxford
international
beaumont
street
oxfordshire
Prior art date
Application number
SG11201809413RA
Other languages
English (en)
Inventor
Ewan Hunter
Howard Womersley
Aroul Ramadass
Alexandre Akoulitchev
Original Assignee
Oxford Biodynamics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford Biodynamics Ltd filed Critical Oxford Biodynamics Ltd
Publication of SG11201809413RA publication Critical patent/SG11201809413RA/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00Reaction characterised by the enzymatic activity
    • C12Q2521/50Other enzymatic activities
    • C12Q2521/501Ligase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00Reactions characterised by treatment of reaction samples
    • C12Q2523/10Characterised by chemical treatment
    • C12Q2523/101Crosslinking agents, e.g. psoralen
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50Detection characterised by immobilisation to a surface
    • C12Q2565/501Detection characterised by immobilisation to a surface being an array of oligonucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
SG11201809413RA 2016-05-06 2017-05-08 Detection of chromosome interaction relevant to breast cancer SG11201809413RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1608000.4A GB201608000D0 (en) 2016-05-06 2016-05-06 Chromosome detection
PCT/GB2017/051273 WO2017191477A1 (en) 2016-05-06 2017-05-08 Detection of chromosome interaction relevant to breast cancer

Publications (1)

Publication Number Publication Date
SG11201809413RA true SG11201809413RA (en) 2018-11-29

Family

ID=56297311

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201809413RA SG11201809413RA (en) 2016-05-06 2017-05-08 Detection of chromosome interaction relevant to breast cancer

Country Status (13)

Country Link
US (1) US11746378B2 (ja)
EP (1) EP3452612B1 (ja)
JP (1) JP7005596B2 (ja)
KR (1) KR102453393B1 (ja)
CN (1) CN109661477B (ja)
AU (1) AU2017261442B2 (ja)
CA (1) CA3023156A1 (ja)
GB (1) GB201608000D0 (ja)
MY (1) MY195357A (ja)
PL (1) PL3452612T3 (ja)
SG (1) SG11201809413RA (ja)
WO (1) WO2017191477A1 (ja)
ZA (1) ZA201806917B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3510152A4 (en) 2016-09-07 2020-04-29 Flagship Pioneering, Inc. METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION
EP4357463A2 (en) 2016-12-01 2024-04-24 Oxford BioDynamics PLC Application of epigenetic chromsomal interactions in cancer diagnostics
DK3565891T3 (da) 2017-01-09 2023-07-24 Whitehead Inst Biomedical Res Fremgangsmåder til ændring af genekspression ved forstyrrelse af transkriptionsfaktor-multimere, der strukturerer regulatoriske sløjfer
WO2020198704A1 (en) * 2019-03-28 2020-10-01 Phase Genomics, Inc. Systems and methods for karyotyping by sequencing
EP4041894A1 (en) 2019-09-23 2022-08-17 Omega Therapeutics, Inc. COMPOSITIONS AND METHODS FOR MODULATING HEPATOCYTE NUCLEAR FACTOR 4-ALPHA (HNF4a) GENE EXPRESSION
CN111334508B (zh) * 2020-03-11 2022-04-15 潍坊医学院 一种抑制乳腺癌细胞的增殖侵袭转移的基因、表达载体
CN111798919B (zh) * 2020-06-24 2022-11-25 上海交通大学 一种肿瘤新抗原预测方法、预测装置及存储介质
CN113436741B (zh) * 2021-07-16 2023-02-28 四川大学华西医院 基于组织特异增强子区域dna甲基化的肺癌复发预测方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0417740D0 (en) * 2004-08-10 2004-09-08 Uc3 Methods and kit for the prognosis of breast cancer
ES2556113T3 (es) * 2005-07-04 2016-01-13 Erasmus University Medical Center Ensayo de captura en chip (4C) de conformación cromosómica
US20090299640A1 (en) 2005-11-23 2009-12-03 University Of Utah Research Foundation Methods and Compositions Involving Intrinsic Genes
GB0603251D0 (en) 2006-02-17 2006-03-29 Isis Innovation DNA conformation
GB0810051D0 (en) * 2008-06-02 2008-07-09 Oxford Biodynamics Ltd Method of diagnosis
ES2916339T3 (es) 2010-07-09 2022-06-30 Cergentis B V Estrategias de secuenciación de región genómica de interés 3D
WO2012159025A2 (en) 2011-05-18 2012-11-22 Life Technologies Corporation Chromosome conformation analysis
EP2780469A1 (en) 2011-11-18 2014-09-24 Vanderbilt University Markers of triple-negative breast cancer and uses thereof
JP6164689B2 (ja) * 2013-08-30 2017-07-19 国立大学法人大阪大学 乳癌術前化学療法に対する感受性の診断補助方法および判定装置
GB201320351D0 (en) * 2013-11-18 2014-01-01 Erasmus Universiteit Medisch Ct Method
AU2015230677A1 (en) 2014-03-11 2016-10-27 The Council Of The Queensland Institute Of Medical Research Determining cancer agressiveness, prognosis and responsiveness to treatment
EP3314018A1 (en) 2015-06-24 2018-05-02 Oxford Biodynamics Limited Detection processes using sites of chromosome interaction

Also Published As

Publication number Publication date
ZA201806917B (en) 2022-06-29
EP3452612A1 (en) 2019-03-13
CN109661477A (zh) 2019-04-19
JP2019521701A (ja) 2019-08-08
EP3452612B1 (en) 2023-08-23
KR20190025814A (ko) 2019-03-12
EP3452612C0 (en) 2023-08-23
PL3452612T3 (pl) 2023-12-11
WO2017191477A1 (en) 2017-11-09
CN109661477B (zh) 2022-12-02
US11746378B2 (en) 2023-09-05
JP7005596B2 (ja) 2022-03-03
KR102453393B1 (ko) 2022-10-11
MY195357A (en) 2023-01-16
GB201608000D0 (en) 2016-06-22
AU2017261442A1 (en) 2018-11-22
US20190241964A1 (en) 2019-08-08
CA3023156A1 (en) 2017-11-09
AU2017261442B2 (en) 2020-05-21

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