SG11201806125UA - Novel bisphosphonic acid compound - Google Patents
Novel bisphosphonic acid compoundInfo
- Publication number
- SG11201806125UA SG11201806125UA SG11201806125UA SG11201806125UA SG11201806125UA SG 11201806125U A SG11201806125U A SG 11201806125UA SG 11201806125U A SG11201806125U A SG 11201806125UA SG 11201806125U A SG11201806125U A SG 11201806125UA SG 11201806125U A SG11201806125U A SG 11201806125UA
- Authority
- SG
- Singapore
- Prior art keywords
- acid compound
- bisphosphonic acid
- novel bisphosphonic
- novel
- compound
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/386—Polyphosphonic acids containing hydroxy substituents in the hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3843—Polyphosphonic acids containing no further substituents than -PO3H2 groups
- C07F9/3852—Cycloaliphatic derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3856—Polyphosphonic acids containing halogen or nitro(so) substituents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3865—Polyphosphonic acids containing sulfur substituents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016027405 | 2016-01-29 | ||
| PCT/JP2017/002855 WO2017131127A1 (ja) | 2016-01-29 | 2017-01-27 | 新規ビスホスホン酸化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201806125UA true SG11201806125UA (en) | 2018-08-30 |
Family
ID=59398507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201806125UA SG11201806125UA (en) | 2016-01-29 | 2017-01-27 | Novel bisphosphonic acid compound |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US10689408B2 (zh) |
| EP (1) | EP3409679A4 (zh) |
| JP (1) | JP6259957B2 (zh) |
| KR (1) | KR20180111791A (zh) |
| CN (1) | CN108473518B (zh) |
| AR (1) | AR107472A1 (zh) |
| AU (1) | AU2017211464B9 (zh) |
| BR (1) | BR112018015552A2 (zh) |
| CA (1) | CA3012957A1 (zh) |
| CO (1) | CO2018007788A2 (zh) |
| HK (1) | HK1257616A1 (zh) |
| MX (1) | MX2018009231A (zh) |
| MY (1) | MY195906A (zh) |
| PH (1) | PH12018501586A1 (zh) |
| RU (1) | RU2731615C2 (zh) |
| SG (1) | SG11201806125UA (zh) |
| TW (1) | TWI730039B (zh) |
| WO (1) | WO2017131127A1 (zh) |
| ZA (1) | ZA201804945B (zh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102651652B1 (ko) | 2018-10-11 | 2024-03-26 | 사니핏 테라퓨틱스 에스.에이. | 이소성 석회화의 치료를 위한 이노시톨 포스페이트 |
| EP4015494A1 (en) | 2020-12-15 | 2022-06-22 | Sanifit Therapeutics S.A. | Processes for the preparation of soluble salts of inositol phosphates |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3540150A1 (de) | 1985-11-13 | 1987-05-14 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| DD298267A5 (de) * | 1989-01-27 | 1992-02-13 | Zentralinstitut Fuer Molekularbiologie,De | Verfahren zur immobilisierung von lipase, beta-galactosidase oder invertase |
| FI89366C (fi) * | 1990-12-20 | 1993-09-27 | Leiras Oy | Foerfarande foer framstaellning av nya farmakologiskt anvaendbara metylenbisfosfonsyraderivat |
| FI89364C (fi) * | 1990-12-20 | 1993-09-27 | Leiras Oy | Foerfarande foer framstaellning av nya, farmakologiskt anvaendbara metylenbisfosfonsyraderivat |
| JPH07507315A (ja) | 1992-05-29 | 1995-08-10 | プロクター、エンド、ギャンブル、ファーマスーティカルズ、インコーポレーテッド | カルシウムおよびホスフェート代謝異常治療用含硫ホスホネート化合物 |
| ES2111163T3 (es) * | 1992-06-30 | 1998-03-01 | Procter & Gamble Pharma | Uso de fosfonatos para el tratamiento de la osteoporosis. |
| AU2756701A (en) | 2000-01-04 | 2001-07-16 | Regents Of The University Of California, The | Use of low dosage bisphosphonates to inhibit cardiac and arterial calcification |
| TW200410700A (en) | 2002-10-15 | 2004-07-01 | Novartis Ag | New uses of and devices comprising bisphosphonates |
| CN1705486A (zh) * | 2002-10-15 | 2005-12-07 | 诺瓦提斯公司 | 用于治疗动脉粥样硬化的双膦酸类化合物和包含它们的装置 |
| US8012949B2 (en) | 2004-10-08 | 2011-09-06 | The Board Of Trustees Of The University Of Illinois | Bisphosphonate compounds and methods with enhanced potency for multiple targets including FPPS, GGPPS, and DPPS |
| JP2009530414A (ja) * | 2006-03-17 | 2009-08-27 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ | ビスホスホネート化合物及び方法 |
| FR2926080B1 (fr) * | 2008-01-03 | 2010-04-02 | Univ Nantes | Procede de synthese de derives d'acide hydroxy-bisphosphonique |
-
2017
- 2017-01-26 TW TW106103144A patent/TWI730039B/zh not_active IP Right Cessation
- 2017-01-27 US US16/073,285 patent/US10689408B2/en active Active
- 2017-01-27 AR ARP170100221A patent/AR107472A1/es unknown
- 2017-01-27 AU AU2017211464A patent/AU2017211464B9/en not_active Expired - Fee Related
- 2017-01-27 KR KR1020187019303A patent/KR20180111791A/ko unknown
- 2017-01-27 CA CA3012957A patent/CA3012957A1/en not_active Abandoned
- 2017-01-27 EP EP17744357.9A patent/EP3409679A4/en not_active Withdrawn
- 2017-01-27 RU RU2018130994A patent/RU2731615C2/ru active
- 2017-01-27 MX MX2018009231A patent/MX2018009231A/es unknown
- 2017-01-27 WO PCT/JP2017/002855 patent/WO2017131127A1/ja active Application Filing
- 2017-01-27 SG SG11201806125UA patent/SG11201806125UA/en unknown
- 2017-01-27 JP JP2017538251A patent/JP6259957B2/ja not_active Expired - Fee Related
- 2017-01-27 BR BR112018015552-7A patent/BR112018015552A2/pt not_active IP Right Cessation
- 2017-01-27 MY MYPI2018702485A patent/MY195906A/en unknown
- 2017-01-27 CN CN201780006981.2A patent/CN108473518B/zh not_active Expired - Fee Related
-
2018
- 2018-07-23 ZA ZA2018/04945A patent/ZA201804945B/en unknown
- 2018-07-25 PH PH12018501586A patent/PH12018501586A1/en unknown
- 2018-07-27 CO CONC2018/0007788A patent/CO2018007788A2/es unknown
- 2018-12-28 HK HK18116739.2A patent/HK1257616A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1257616A1 (zh) | 2019-10-25 |
| AR107472A1 (es) | 2018-05-02 |
| AU2017211464B9 (en) | 2021-07-22 |
| US10689408B2 (en) | 2020-06-23 |
| RU2731615C2 (ru) | 2020-09-07 |
| TW201728332A (zh) | 2017-08-16 |
| AU2017211464A1 (en) | 2018-08-09 |
| CN108473518A (zh) | 2018-08-31 |
| JP6259957B2 (ja) | 2018-01-10 |
| MX2018009231A (es) | 2018-11-09 |
| WO2017131127A1 (ja) | 2017-08-03 |
| CO2018007788A2 (es) | 2018-08-10 |
| MY195906A (en) | 2023-02-27 |
| EP3409679A4 (en) | 2019-11-06 |
| CA3012957A1 (en) | 2017-08-03 |
| BR112018015552A2 (pt) | 2018-12-26 |
| US20190002482A1 (en) | 2019-01-03 |
| AU2017211464B2 (en) | 2021-07-01 |
| ZA201804945B (en) | 2019-09-25 |
| PH12018501586A1 (en) | 2019-04-08 |
| EP3409679A1 (en) | 2018-12-05 |
| KR20180111791A (ko) | 2018-10-11 |
| CN108473518B (zh) | 2021-07-06 |
| JPWO2017131127A1 (ja) | 2018-02-01 |
| RU2018130994A (ru) | 2020-03-03 |
| TWI730039B (zh) | 2021-06-11 |
| RU2018130994A3 (zh) | 2020-03-13 |
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