SG11201803816RA - Targeting of the formyl-peptide receptor 2/lipoxin a4 receptor (fpr2/alx) for treatment of heart disease - Google Patents

Targeting of the formyl-peptide receptor 2/lipoxin a4 receptor (fpr2/alx) for treatment of heart disease

Info

Publication number
SG11201803816RA
SG11201803816RA SG11201803816RA SG11201803816RA SG11201803816RA SG 11201803816R A SG11201803816R A SG 11201803816RA SG 11201803816R A SG11201803816R A SG 11201803816RA SG 11201803816R A SG11201803816R A SG 11201803816RA SG 11201803816R A SG11201803816R A SG 11201803816RA
Authority
SG
Singapore
Prior art keywords
international
receptor
bristol
new jersey
pennington
Prior art date
Application number
SG11201803816RA
Other languages
English (en)
Inventor
Jacek Ostrowski
Ricardo Garcia
Nicholas R Wurtz
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of SG11201803816RA publication Critical patent/SG11201803816RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/41521,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11201803816RA 2015-11-24 2016-11-21 Targeting of the formyl-peptide receptor 2/lipoxin a4 receptor (fpr2/alx) for treatment of heart disease SG11201803816RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562259498P 2015-11-24 2015-11-24
PCT/US2016/063036 WO2017091496A1 (en) 2015-11-24 2016-11-21 Targeting of the formyl-peptide receptor 2/lipoxin a4 receptor (fpr2/alx) for treatment of heart disease

Publications (1)

Publication Number Publication Date
SG11201803816RA true SG11201803816RA (en) 2018-06-28

Family

ID=57544530

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201803816RA SG11201803816RA (en) 2015-11-24 2016-11-21 Targeting of the formyl-peptide receptor 2/lipoxin a4 receptor (fpr2/alx) for treatment of heart disease

Country Status (13)

Country Link
US (1) US20180325869A1 (pt)
EP (1) EP3380091A1 (pt)
JP (1) JP2018538367A (pt)
KR (1) KR20180081528A (pt)
CN (1) CN108348479A (pt)
AU (1) AU2016359463A1 (pt)
BR (1) BR112018010155A8 (pt)
CA (1) CA3006291A1 (pt)
EA (1) EA201891007A1 (pt)
IL (1) IL259468A (pt)
MX (1) MX2018005756A (pt)
SG (1) SG11201803816RA (pt)
WO (1) WO2017091496A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017100390A1 (en) 2015-12-10 2017-06-15 Bristol-Myers Squibb Company Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists
JP7098663B2 (ja) * 2017-06-09 2022-07-11 ブリストル-マイヤーズ スクイブ カンパニー ピペリジノンホルミルペプチド2受容体アゴニスト
WO2018227065A1 (en) * 2017-06-09 2018-12-13 Bristol-Myers Squibb Company Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists
JP7094989B2 (ja) * 2017-06-09 2022-07-04 ブリストル-マイヤーズ スクイブ カンパニー シクロプロピルウレアホルミルペプチド2受容体およびホルミルペプチド1受容体アゴニスト
KR102615099B1 (ko) 2017-06-09 2023-12-15 브리스톨-마이어스 스큅 컴퍼니 아릴 헤테로시클릭 피페리디논 포르밀 펩티드 2 수용체 및 포르밀 펩티드 1 수용체 효능제
EA202092094A1 (ru) 2018-03-05 2020-12-10 Бристол-Маерс Сквибб Компани Фенилпирролидиноновые агонисты формилпептидного рецептора 2

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE520689T1 (de) * 2007-12-18 2011-09-15 Actelion Pharmaceuticals Ltd Aminotriazolderivate als alx-agonisten
ES2553635T3 (es) * 2010-11-17 2015-12-10 Actelion Pharmaceuticals Ltd. Derivados de éster spiro[2.4]heptano puenteados
CN104284887B (zh) * 2012-05-16 2016-06-22 埃科特莱茵药品有限公司 作为alx受体激动剂的经1-(对-甲苯基)环丙基取代的桥联螺[2.4]庚烷衍生物
WO2017100390A1 (en) * 2015-12-10 2017-06-15 Bristol-Myers Squibb Company Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists
EA202092094A1 (ru) * 2018-03-05 2020-12-10 Бристол-Маерс Сквибб Компани Фенилпирролидиноновые агонисты формилпептидного рецептора 2

Also Published As

Publication number Publication date
IL259468A (en) 2018-07-31
US20180325869A1 (en) 2018-11-15
AU2016359463A1 (en) 2018-07-12
MX2018005756A (es) 2018-08-01
BR112018010155A2 (pt) 2018-11-21
KR20180081528A (ko) 2018-07-16
BR112018010155A8 (pt) 2019-02-26
EA201891007A1 (ru) 2018-11-30
CN108348479A (zh) 2018-07-31
WO2017091496A1 (en) 2017-06-01
EP3380091A1 (en) 2018-10-03
JP2018538367A (ja) 2018-12-27
CA3006291A1 (en) 2017-06-01

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