SG11201704424PA - Primitive gut endoderm cells and method for producing same - Google Patents
Primitive gut endoderm cells and method for producing sameInfo
- Publication number
- SG11201704424PA SG11201704424PA SG11201704424PA SG11201704424PA SG11201704424PA SG 11201704424P A SG11201704424P A SG 11201704424PA SG 11201704424P A SG11201704424P A SG 11201704424PA SG 11201704424P A SG11201704424P A SG 11201704424PA SG 11201704424P A SG11201704424P A SG 11201704424PA
- Authority
- SG
- Singapore
- Prior art keywords
- endoderm cells
- producing same
- primitive gut
- gut endoderm
- primitive
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/407—Liver; Hepatocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/12—Hepatocyte growth factor [HGF]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/165—Vascular endothelial growth factor [VEGF]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/415—Wnt; Frizzeled
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases (EC 2.)
- C12N2501/727—Kinases (EC 2.7.)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0679—Cells of the gastro-intestinal tract
- C12N5/068—Stem cells; Progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physiology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nutrition Science (AREA)
- Transplantation (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014248694A JP5777127B1 (ja) | 2014-12-09 | 2014-12-09 | 原始腸内胚葉細胞及びその作製方法 |
PCT/JP2015/084379 WO2016093222A1 (fr) | 2014-12-09 | 2015-12-08 | Cellules primitives d'endoderme d'intestin et leur procédé de production |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201704424PA true SG11201704424PA (en) | 2017-07-28 |
Family
ID=54192598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201704424PA SG11201704424PA (en) | 2014-12-09 | 2015-12-08 | Primitive gut endoderm cells and method for producing same |
Country Status (8)
Country | Link |
---|---|
US (1) | US10370638B2 (fr) |
EP (1) | EP3239294A4 (fr) |
JP (1) | JP5777127B1 (fr) |
KR (1) | KR102453717B1 (fr) |
CN (1) | CN107208056B (fr) |
CA (1) | CA2969194C (fr) |
SG (1) | SG11201704424PA (fr) |
WO (1) | WO2016093222A1 (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6869543B2 (ja) | 2015-12-22 | 2021-05-12 | 公立大学法人横浜市立大学 | ウイルス感染モデル、その作製方法及びその利用 |
BR112018012070A2 (pt) | 2015-12-24 | 2018-11-27 | Public University Corporation Yokohama City University | método para a produção de tecidos/ órgãos utilizando células sanguíneas |
US11473061B2 (en) | 2016-02-01 | 2022-10-18 | Cedars-Sinai Medical Center | Systems and methods for growth of intestinal cells in microfluidic devices |
JP7209619B2 (ja) * | 2016-07-28 | 2023-01-20 | エフ.ホフマン-ラ ロシュ アーゲー | 非ヒト霊長類人工多能性幹細胞由来肝細胞およびその使用 |
US11913022B2 (en) | 2017-01-25 | 2024-02-27 | Cedars-Sinai Medical Center | In vitro induction of mammary-like differentiation from human pluripotent stem cells |
US11767513B2 (en) | 2017-03-14 | 2023-09-26 | Cedars-Sinai Medical Center | Neuromuscular junction |
US11414648B2 (en) | 2017-03-24 | 2022-08-16 | Cedars-Sinai Medical Center | Methods and compositions for production of fallopian tube epithelium |
CN110691845A (zh) | 2017-05-09 | 2020-01-14 | 公立大学法人名古屋市立大学 | 由多能干细胞制作肠道类器官的方法 |
EP3625331A4 (fr) * | 2017-05-19 | 2021-02-24 | Cedars-Sinai Medical Center | Systèmes et méthodes de croissance de cellules intestinales |
JP7233717B2 (ja) * | 2017-11-30 | 2023-03-07 | 公立大学法人横浜市立大学 | 多能性幹細胞からの立体臓器の構築 |
EP3778870A4 (fr) | 2018-03-28 | 2022-01-05 | Public University Corporation Yokohama City University | Procédé de fusion de masses cellulaires |
US11981918B2 (en) | 2018-04-06 | 2024-05-14 | Cedars-Sinai Medical Center | Differentiation technique to generate dopaminergic neurons from induced pluripotent stem cells |
WO2020091020A1 (fr) | 2018-11-02 | 2020-05-07 | 公立大学法人名古屋市立大学 | Procédé de production d'un organoïde intestinal dérivé de cellules souches pluripotentes |
CN111849859B (zh) * | 2019-04-04 | 2023-04-07 | 中国科学院分子细胞科学卓越创新中心 | 一种经基因编辑的功能性肝实质细胞的制备方法及其应用 |
MX2022011245A (es) | 2020-03-11 | 2023-01-11 | Bit Bio Ltd | Método de generación de células hepáticas. |
TW202216158A (zh) * | 2020-07-10 | 2022-05-01 | 國立研究開發法人理化學研究所 | 網膜色素上皮細胞之移植用存活促進劑 |
US20230365925A1 (en) * | 2020-10-09 | 2023-11-16 | Center For Excellence In Molecular Cell Science, Chinese Academy Of Sciences | Method for Inducing Differentiated Cells Into Pluripotent Endoderm Stem Cells and Application Thereof |
WO2024026313A1 (fr) | 2022-07-25 | 2024-02-01 | The Regents Of The University Of California | Procédés de production et d'utilisation de cellules souches embryonnaires aviaires et d'organoïdes télencéphaliques aviaires |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101445791A (zh) * | 2008-12-04 | 2009-06-03 | 北京大学 | 一种筛选多潜能细胞的方法及其专用培养基 |
CN103857787B (zh) | 2011-09-27 | 2019-05-17 | 公立大学法人横滨市立大学 | 组织和器官的制作方法 |
CN105062961A (zh) | 2012-05-23 | 2015-11-18 | 弗·哈夫曼-拉罗切有限公司 | 获得和使用内胚层和肝细胞的组合物和方法 |
AU2014218290B2 (en) * | 2013-02-18 | 2020-03-12 | The Hospital For Sick Children | Methods for generating hepatocytes and cholangiocytes from pluripotent stem cells |
CN103194424A (zh) * | 2013-03-28 | 2013-07-10 | 于涛 | 一种诱导胚胎干细胞为胰腺组织样细胞的方法 |
AU2014248167B2 (en) * | 2013-04-03 | 2019-10-10 | FUJIFILM Cellular Dynamics, Inc. | Methods and compositions for culturing endoderm progenitor cells in suspension |
-
2014
- 2014-12-09 JP JP2014248694A patent/JP5777127B1/ja active Active
-
2015
- 2015-12-08 CN CN201580066955.XA patent/CN107208056B/zh active Active
- 2015-12-08 SG SG11201704424PA patent/SG11201704424PA/en unknown
- 2015-12-08 US US15/534,205 patent/US10370638B2/en active Active
- 2015-12-08 KR KR1020177018234A patent/KR102453717B1/ko active IP Right Grant
- 2015-12-08 CA CA2969194A patent/CA2969194C/fr active Active
- 2015-12-08 WO PCT/JP2015/084379 patent/WO2016093222A1/fr active Application Filing
- 2015-12-08 EP EP15868455.5A patent/EP3239294A4/fr active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3239294A4 (fr) | 2018-06-13 |
US20170335277A1 (en) | 2017-11-23 |
KR20170092637A (ko) | 2017-08-11 |
CN107208056B (zh) | 2021-07-30 |
US10370638B2 (en) | 2019-08-06 |
EP3239294A1 (fr) | 2017-11-01 |
CA2969194C (fr) | 2023-08-01 |
CA2969194A1 (fr) | 2016-06-06 |
CN107208056A (zh) | 2017-09-26 |
JP5777127B1 (ja) | 2015-09-09 |
KR102453717B1 (ko) | 2022-10-11 |
JP2016106591A (ja) | 2016-06-20 |
WO2016093222A1 (fr) | 2016-06-16 |
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