SG11201704424PA - Primitive gut endoderm cells and method for producing same - Google Patents

Primitive gut endoderm cells and method for producing same

Info

Publication number
SG11201704424PA
SG11201704424PA SG11201704424PA SG11201704424PA SG11201704424PA SG 11201704424P A SG11201704424P A SG 11201704424PA SG 11201704424P A SG11201704424P A SG 11201704424PA SG 11201704424P A SG11201704424P A SG 11201704424PA SG 11201704424P A SG11201704424P A SG 11201704424PA
Authority
SG
Singapore
Prior art keywords
endoderm cells
producing same
primitive gut
gut endoderm
primitive
Prior art date
Application number
SG11201704424PA
Inventor
Takanori Takebe
Hideki Taniguchi
ran ran Zhang
Original Assignee
Public Univ Corp Yokohama City Univ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Public Univ Corp Yokohama City Univ filed Critical Public Univ Corp Yokohama City Univ
Publication of SG11201704424PA publication Critical patent/SG11201704424PA/en

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    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/407—Liver; Hepatocytes
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/12—Hepatocyte growth factor [HGF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/165—Vascular endothelial growth factor [VEGF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/415—Wnt; Frizzeled
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases (EC 2.)
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
    • C—CHEMISTRY; METALLURGY
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • C—CHEMISTRY; METALLURGY
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • C12N5/068—Stem cells; Progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
SG11201704424PA 2014-12-09 2015-12-08 Primitive gut endoderm cells and method for producing same SG11201704424PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014248694A JP5777127B1 (en) 2014-12-09 2014-12-09 Primordial gut endoderm cells and method for producing the same
PCT/JP2015/084379 WO2016093222A1 (en) 2014-12-09 2015-12-08 Primitive gut endoderm cells and method for producing same

Publications (1)

Publication Number Publication Date
SG11201704424PA true SG11201704424PA (en) 2017-07-28

Family

ID=54192598

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201704424PA SG11201704424PA (en) 2014-12-09 2015-12-08 Primitive gut endoderm cells and method for producing same

Country Status (8)

Country Link
US (1) US10370638B2 (en)
EP (1) EP3239294A4 (en)
JP (1) JP5777127B1 (en)
KR (1) KR102453717B1 (en)
CN (1) CN107208056B (en)
CA (1) CA2969194C (en)
SG (1) SG11201704424PA (en)
WO (1) WO2016093222A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017110931A1 (en) 2015-12-22 2017-06-29 公立大学法人横浜市立大学 Virus infection model, preparation method therefor, and utilization thereof
SG11201804755VA (en) 2015-12-24 2018-07-30 Public Univ Corp Yokohama City Univ Method for manufacturing tissue/organ by using blood cells
EP3411470A4 (en) 2016-02-01 2019-10-09 Emulate, Inc. Systems and methods for growth of intestinal cells in microfluidic devices
CN109563477A (en) * 2016-07-28 2019-04-02 豪夫迈·罗氏有限公司 The pluripotent stem cell derivative type liver cell and application thereof of non-human primates induction
WO2018140647A1 (en) 2017-01-25 2018-08-02 Cedars-Sinai Medical Center In vitro induction of mammary-like differentiation from human pluripotent stem cells
US11767513B2 (en) 2017-03-14 2023-09-26 Cedars-Sinai Medical Center Neuromuscular junction
US11414648B2 (en) 2017-03-24 2022-08-16 Cedars-Sinai Medical Center Methods and compositions for production of fallopian tube epithelium
US11859212B2 (en) 2017-05-09 2024-01-02 Public University Corporation Nagoya City University Method for producing intestinal organoid derived from pluripotent stem cells
WO2018213773A1 (en) * 2017-05-19 2018-11-22 Cedars-Sinai Medical Center Systems and methods for growth of intestinal cells
US20200362315A1 (en) * 2017-11-30 2020-11-19 Public University Corporation Yokohama City University Formation of Three-Dimensional Organ from Pluripotent Stem Cells
EP3778870A4 (en) 2018-03-28 2022-01-05 Public University Corporation Yokohama City University Cell mass fusion method
JP7367992B2 (en) 2018-11-02 2023-10-24 公立大学法人名古屋市立大学 Method for producing pluripotent stem cell-derived intestinal organoids
CN111849859B (en) * 2019-04-04 2023-04-07 中国科学院分子细胞科学卓越创新中心 Preparation method and application of gene-edited functional liver parenchymal cells
CA3175071A1 (en) 2020-03-11 2021-09-16 Bit Bio Limited Method of generating hepatic cells
JPWO2022009969A1 (en) * 2020-07-10 2022-01-13
AU2020471426A1 (en) * 2020-10-09 2023-06-08 Center For Excellence In Molecular Cell Science, Chinese Academy Of Sciences Method for inducing differentiated cells into pluripotent endoderm stem cells and application thereof
WO2024026313A1 (en) 2022-07-25 2024-02-01 The Regents Of The University Of California Methods of producing and using avian embryonic stem cells and avian telencephalic organoids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101445791A (en) * 2008-12-04 2009-06-03 北京大学 Method for screening pluripotent cell and special culture medium thereof
EP2762558A4 (en) 2011-09-27 2015-05-20 Public Univ Corp Yokohama City Method for producing tissue and organ
EP2852661A1 (en) 2012-05-23 2015-04-01 F. Hoffmann-La Roche AG Compositions and methods of obtaining and using endoderm and hepatocyte cells
KR20240024355A (en) * 2013-02-18 2024-02-23 유니버시티 헬스 네트워크 Methods for generating hepatocytes and cholangiocytes from pluripotent stem cells
CN103194424A (en) * 2013-03-28 2013-07-10 于涛 Method for inducing embryonic stem cell into pancreatic tissue-like cells
AU2014248167B2 (en) 2013-04-03 2019-10-10 FUJIFILM Cellular Dynamics, Inc. Methods and compositions for culturing endoderm progenitor cells in suspension

Also Published As

Publication number Publication date
CN107208056A (en) 2017-09-26
EP3239294A1 (en) 2017-11-01
CN107208056B (en) 2021-07-30
JP5777127B1 (en) 2015-09-09
EP3239294A4 (en) 2018-06-13
US10370638B2 (en) 2019-08-06
KR20170092637A (en) 2017-08-11
US20170335277A1 (en) 2017-11-23
CA2969194C (en) 2023-08-01
WO2016093222A1 (en) 2016-06-16
KR102453717B1 (en) 2022-10-11
JP2016106591A (en) 2016-06-20
CA2969194A1 (en) 2016-06-06

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