SG11201704165VA - Targeted gas-filled microvesicles formulation - Google Patents

Targeted gas-filled microvesicles formulation

Info

Publication number
SG11201704165VA
SG11201704165VA SG11201704165VA SG11201704165VA SG11201704165VA SG 11201704165V A SG11201704165V A SG 11201704165VA SG 11201704165V A SG11201704165V A SG 11201704165VA SG 11201704165V A SG11201704165V A SG 11201704165VA SG 11201704165V A SG11201704165V A SG 11201704165VA
Authority
SG
Singapore
Prior art keywords
formulation
targeted gas
filled microvesicles
microvesicles
targeted
Prior art date
Application number
SG11201704165VA
Other languages
English (en)
Inventor
Philippe Bussat
Anne Lassus
Original Assignee
Bracco Suisse Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Suisse Sa filed Critical Bracco Suisse Sa
Publication of SG11201704165VA publication Critical patent/SG11201704165VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48Diagnostic techniques
    • A61B8/481Diagnostic techniques involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/226Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acoustics & Sound (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
SG11201704165VA 2014-12-18 2015-12-17 Targeted gas-filled microvesicles formulation SG11201704165VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14199057 2014-12-18
PCT/EP2015/080199 WO2016097130A1 (fr) 2014-12-18 2015-12-17 Composition ciblée à base de microvésicules remplies d'un gaz

Publications (1)

Publication Number Publication Date
SG11201704165VA true SG11201704165VA (en) 2017-07-28

Family

ID=52292644

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201704165VA SG11201704165VA (en) 2014-12-18 2015-12-17 Targeted gas-filled microvesicles formulation

Country Status (15)

Country Link
US (3) US10682429B2 (fr)
EP (1) EP3233136B8 (fr)
JP (1) JP6803839B2 (fr)
KR (1) KR102190157B1 (fr)
CN (2) CN113209316A (fr)
BR (1) BR112017011258B1 (fr)
CA (1) CA2968478C (fr)
DK (1) DK3233136T3 (fr)
ES (1) ES2726924T3 (fr)
HU (1) HUE043680T2 (fr)
IL (1) IL252960A0 (fr)
RU (1) RU2725808C2 (fr)
SG (1) SG11201704165VA (fr)
SI (1) SI3233136T1 (fr)
WO (1) WO2016097130A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL298236B2 (en) * 2015-12-21 2024-05-01 Nuvox Pharma Llc Preparations containing a nanoemulsion of fluorocarbons and methods for their preparation
WO2018140425A1 (fr) * 2017-01-24 2018-08-02 Nuvox Pharma Llc Formulations thérapeutiques à base d'oxygène iso-osmotique et quasi iso-osmotique et procédés associés
GB201821049D0 (en) * 2018-12-21 2019-02-06 Ge Healthcare As Ultrasound contrast agent and methods for use therof
JP2022513886A (ja) * 2018-12-21 2022-02-09 ブラッコ・スイス・ソシエテ・アノニム リガンドを含むガス充填微小胞
US20200360289A1 (en) * 2019-05-15 2020-11-19 Bracco Suisse Sa Freeze-dried product and gas-filled microvesicles suspension
US11717570B2 (en) 2019-05-15 2023-08-08 Bracco Suisse Sa Gas-filled microvesicles
WO2021160659A1 (fr) * 2020-02-11 2021-08-19 Bracco Suisse Sa Microvésicules remplies de gaz pour utilisation thérapeutique

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556610A (en) 1992-01-24 1996-09-17 Bracco Research S.A. Gas mixtures useful as ultrasound contrast media, contrast agents containing the media and method
IN172208B (fr) 1990-04-02 1993-05-01 Sint Sa
US5445813A (en) 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them
IL116328A (en) 1994-12-16 1999-09-22 Bracco Research Sa Frozen suspension of gas microbubbles in frozen aqueous carrier for use as contrast agent in ultrasonic imaging
IL125748A (en) 1996-02-19 2002-05-23 Nycomed Imaging As Contrast-containing gases for use in diagnostic imaging
JP2006514915A (ja) 2002-03-01 2006-05-18 ダイアックス、コープ Kdrおよびvegf/kdr結合ペプチドならびに診断および治療におけるその使用
ES2523654T3 (es) 2002-03-01 2014-11-28 Bracco Suisse Sa Constructos multivalentes para aplicaciones terapéuticas y de diagnóstico
US7794693B2 (en) * 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
WO2004069284A2 (fr) 2003-02-04 2004-08-19 Bracco International B.V. Agents de contraste pour ultrasons et procede pour leur elaboration
EP2359864B1 (fr) * 2005-12-09 2019-04-17 Bracco Suisse SA Conjugués vecteur de ciblage-phospholipide
CN101528197B (zh) * 2006-10-06 2013-02-13 Scil技术股份有限公司 药物应用的干燥重建囊泡制剂
BR112013003393B1 (pt) * 2010-08-09 2021-07-13 Bracco Suisse Sa Suspensão aquosa compreendendo microvesícula cheia com gás e precursor da referida microvesícula

Also Published As

Publication number Publication date
JP2018500294A (ja) 2018-01-11
IL252960A0 (en) 2017-08-31
RU2017125459A (ru) 2019-01-21
EP3233136B8 (fr) 2019-04-10
BR112017011258A2 (pt) 2018-04-03
CN107206110A (zh) 2017-09-26
ES2726924T3 (es) 2019-10-10
BR112017011258B1 (pt) 2024-02-06
RU2725808C2 (ru) 2020-07-06
KR102190157B1 (ko) 2020-12-14
WO2016097130A1 (fr) 2016-06-23
US20210386872A1 (en) 2021-12-16
US10682429B2 (en) 2020-06-16
CA2968478A1 (fr) 2016-06-23
CN107206110B (zh) 2021-07-20
US20180008731A1 (en) 2018-01-11
SI3233136T1 (sl) 2019-08-30
US11071792B2 (en) 2021-07-27
JP6803839B2 (ja) 2020-12-23
EP3233136A1 (fr) 2017-10-25
RU2017125459A3 (fr) 2019-06-19
US20200330620A1 (en) 2020-10-22
DK3233136T3 (da) 2019-05-20
CA2968478C (fr) 2021-10-12
EP3233136B1 (fr) 2019-02-20
CN113209316A (zh) 2021-08-06
HUE043680T2 (hu) 2019-09-30
KR20170097672A (ko) 2017-08-28

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