SG11201701278RA - Methods for production of oxygenated terpenes - Google Patents

Methods for production of oxygenated terpenes

Info

Publication number
SG11201701278RA
SG11201701278RA SG11201701278RA SG11201701278RA SG11201701278RA SG 11201701278R A SG11201701278R A SG 11201701278RA SG 11201701278R A SG11201701278R A SG 11201701278RA SG 11201701278R A SG11201701278R A SG 11201701278RA SG 11201701278R A SG11201701278R A SG 11201701278RA
Authority
SG
Singapore
Prior art keywords
production
methods
oxygenated terpenes
terpenes
oxygenated
Prior art date
Application number
SG11201701278RA
Other languages
English (en)
Inventor
Ajikumar Parayil Kumaran
Chin Giaw Lim
Liwei Li
Souvik Ghosh
Christopher Pirie
Anthony Qualley
Original Assignee
Manus Biosynthesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manus Biosynthesis Inc filed Critical Manus Biosynthesis Inc
Publication of SG11201701278RA publication Critical patent/SG11201701278RA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N27/00—Biocides, pest repellants or attractants, or plant growth regulators containing hydrocarbons
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/10—Natural spices, flavouring agents or condiments; Extracts thereof
    • A23L27/12—Natural spices, flavouring agents or condiments; Extracts thereof from fruit, e.g. essential oils
    • A23L27/13—Natural spices, flavouring agents or condiments; Extracts thereof from fruit, e.g. essential oils from citrus fruits
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0073—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.14.13
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/002—Preparation of hydrocarbons or halogenated hydrocarbons cyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/13—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
    • C12Y114/13078—Ent-kaurene oxidase (1.14.13.78)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
SG11201701278RA 2014-08-21 2015-08-21 Methods for production of oxygenated terpenes SG11201701278RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462040284P 2014-08-21 2014-08-21
PCT/US2015/046369 WO2016029153A1 (en) 2014-08-21 2015-08-21 Methods for production of oxygenated terpenes

Publications (1)

Publication Number Publication Date
SG11201701278RA true SG11201701278RA (en) 2017-03-30

Family

ID=54035332

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201701278RA SG11201701278RA (en) 2014-08-21 2015-08-21 Methods for production of oxygenated terpenes

Country Status (7)

Country Link
US (6) US10934564B2 (ja)
EP (2) EP3183357B1 (ja)
JP (1) JP6735750B2 (ja)
CN (1) CN107002109A (ja)
MY (1) MY185817A (ja)
SG (1) SG11201701278RA (ja)
WO (2) WO2016029153A1 (ja)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6735750B2 (ja) 2014-08-21 2020-08-05 マナス バイオシンセシス インコーポレイテッド 含酸素テルペンの産生方法
EP3337893B1 (en) * 2015-08-21 2023-07-19 Manus Bio Inc. Increasing productivity of e. coli host cells that functionally express p450 enzymes
EP3488008A2 (en) * 2016-07-20 2019-05-29 Firmenich SA Vetiver
CN109890217A (zh) 2016-09-16 2019-06-14 百事可乐公司 用于改善非营养性甜味剂的味道的组合物和方法
EP3536792A4 (en) * 2016-11-04 2020-07-01 Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences RECOMBINANT YEAST AND ASSOCIATED USE
JP7330888B2 (ja) 2017-01-26 2023-08-22 マナス バイオ インコーポレイテッド テルペノイド産物を微生物生産するための代謝工学
BR112019016036A2 (pt) * 2017-02-03 2020-05-26 Manus Bio, Inc. Manipulação metabólica para produção microbiana de produtos terpenoides
CN107723252A (zh) * 2017-09-22 2018-02-23 天津大学 生产巴伦西亚橘烯和诺卡酮的重组解脂耶氏酵母菌及构建方法
WO2019059337A1 (ja) * 2017-09-22 2019-03-28 味の素株式会社 ヌートカトンの製造方法
EP3697898A1 (en) * 2018-01-18 2020-08-26 Firmenich SA Cytochrome p450 monooxygenase catalyzed oxidation of sesquiterpenes
WO2019169027A2 (en) * 2018-02-27 2019-09-06 Manus Bio, Inc. Microbial production of triterpenoids including mogrosides
EP3778910A4 (en) 2018-04-06 2022-01-19 Ajinomoto Co., Inc. PROCESS FOR THE PREPARATION OF 13-HYDROXY-9(Z)-OCTADECEONIC ACID
GB201808663D0 (en) * 2018-05-25 2018-07-11 Innes John Centre Method
WO2020051488A1 (en) * 2018-09-06 2020-03-12 Manus Bio, Inc. Microbial production of rotundone
WO2020072908A1 (en) * 2018-10-05 2020-04-09 Manus Bio, Inc. Biosynthesis and recovery of secondary metabolites
CN109486695B (zh) * 2018-12-26 2021-04-06 浙江医药股份有限公司 用于生产法尼烯的解脂耶氏酵母
CN109913380B (zh) * 2019-03-25 2021-12-10 南京工业大学 生产(-)-α-红没药醇的重组解脂耶氏酵母菌及其构建方法和应用
CN110923249A (zh) * 2019-10-15 2020-03-27 贵州省烟草科学研究院 烟草CyP71及在调控植物表皮毛发育方面的应用
CN111019852B (zh) * 2019-12-31 2021-11-23 江南大学 一种提高酿酒酵母工程菌株合成葡萄糖二酸效率的方法
CN111154665B (zh) * 2020-01-21 2021-02-02 南京工业大学 一株重组解脂耶罗维亚酵母及其构建方法和应用
CN111235046A (zh) * 2020-02-05 2020-06-05 天津大学 异源合成α-檀香烯的重组解脂耶氏酵母及其构建方法
US11939618B2 (en) * 2020-03-23 2024-03-26 The Regents Of The University Of California Fusion proteins useful for modifying terpenes
CN111394290A (zh) * 2020-03-26 2020-07-10 北京化工大学 产长叶烯的基因工程菌及其构建方法与应用
WO2022090464A1 (en) 2020-10-30 2022-05-05 Givaudan Sa Method of mitigating conversion of volatile terpene species
CN116547258A (zh) 2020-10-30 2023-08-04 奇华顿股份有限公司 引起挥发性萜烯物质的转化的方法
CN112391360B (zh) * 2020-11-04 2022-09-06 江南大学 黄酮3β-羟化酶还原酶突变体及其应用
US20240254521A1 (en) * 2021-05-11 2024-08-01 Manus Bio Inc. Enzymes, host cells, and methods for production of rotundone and other terpenoids
CN114181964B (zh) * 2021-11-02 2023-06-09 云南大学 一种表达盒组合、重组载体和重组酿酒酵母及其应用
CN114480512B (zh) * 2021-12-13 2022-10-25 华南理工大学 氧化还原酶及其突变体在生物合成圆柚酮中的应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL121437A (en) * 1995-12-18 2000-10-31 Firmenich & Cie Process for the preparation of nootkatone or nootkatol or of mixtures of these compounds
WO1999025196A1 (fr) 1997-11-17 1999-05-27 Taisho Pharmaceutical Co., Ltd. Insectifuge contre insectes hematophages
GB9825421D0 (en) 1998-11-19 1999-01-13 Isis Innovation Process for oxidising terpenes
US6200786B1 (en) 1999-09-08 2001-03-13 Givaudan S.A. Process for the preparation of nootkatone by laccase catalysis
US6890960B1 (en) 1999-10-19 2005-05-10 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Vetiver oil extracts as termite repellent and toxicant
US7172886B2 (en) 2001-12-06 2007-02-06 The Regents Of The University Of California Biosynthesis of isopentenyl pyrophosphate
JP4139646B2 (ja) * 2002-08-01 2008-08-27 長谷川香料株式会社 香気香味賦与剤
CN101914558B (zh) * 2002-10-04 2013-05-29 弗门尼舍有限公司 倍半萜烯合成酶及其使用方法
ES2607122T3 (es) 2002-10-04 2017-03-29 Firmenich Sa Sesquiterpeno sintasas y procedimientos de uso
US7741089B2 (en) 2003-08-11 2010-06-22 Verenium Corporation Laccases, nucleic acids encoding them and methods for making and using them
DE102004006825A1 (de) 2004-02-11 2005-09-01 Maxens Gmbh Verfahren zur Herstellung von aromaaktiven Terpenen
WO2006079020A2 (en) 2005-01-19 2006-07-27 University Of Kentucky Research Foundation Functional identification of the hyoscyamus muticus gene coding for premnaspirodiene hydroxylase activity
SG181422A1 (en) 2009-11-10 2012-07-30 Massachusetts Inst Technology Microbial engineering for the production of chemical and pharmaceutical products from the isoprenoid pathway
US8927241B2 (en) 2009-11-10 2015-01-06 Massachusetts Institute Of Technology Microbial engineering for the production of chemical and pharmaceutical products from the isoprenoid pathway
CN103282492A (zh) 2010-10-29 2013-09-04 奥利里克斯股份有限公司 修饰的瓦伦烯合酶多肽、编码核酸分子及其用途
EP2645847B1 (en) 2010-11-30 2018-01-17 Massachusetts Institute of Technology Microbial production of natural sweeteners, diterpenoid steviol glycosides
IN2014CN03791A (ja) * 2011-11-09 2015-10-16 Amyris Inc
ES2911701T3 (es) * 2012-11-01 2022-05-20 Univ British Columbia Polipéptidos de citocromo P450 y citocromo P450 reductasa, moléculas de ácido nucleico codificantes y usos de los mismos
KR101559489B1 (ko) 2014-04-08 2015-10-12 한국해양과학기술원 방향타를 이용한 요제어방식 조류발전장치 및 이의 제어방법
JP6735750B2 (ja) 2014-08-21 2020-08-05 マナス バイオシンセシス インコーポレイテッド 含酸素テルペンの産生方法
WO2016073740A1 (en) 2014-11-05 2016-05-12 Manus Biosynthesis, Inc. Microbial production of steviol glycosides
EP3337893B1 (en) 2015-08-21 2023-07-19 Manus Bio Inc. Increasing productivity of e. coli host cells that functionally express p450 enzymes
WO2020051488A1 (en) * 2018-09-06 2020-03-12 Manus Bio, Inc. Microbial production of rotundone

Also Published As

Publication number Publication date
WO2016029187A3 (en) 2016-05-06
US11952608B2 (en) 2024-04-09
US11180782B2 (en) 2021-11-23
CN107002109A (zh) 2017-08-01
EP3183357B1 (en) 2020-03-04
US20200224224A1 (en) 2020-07-16
US11807890B2 (en) 2023-11-07
EP3183353A2 (en) 2017-06-28
JP2017525395A (ja) 2017-09-07
JP6735750B2 (ja) 2020-08-05
US20240141392A1 (en) 2024-05-02
MY185817A (en) 2021-06-10
WO2016029187A2 (en) 2016-02-25
US20180135081A1 (en) 2018-05-17
US10501760B2 (en) 2019-12-10
US20220073955A1 (en) 2022-03-10
US20210292798A1 (en) 2021-09-23
WO2016029153A1 (en) 2016-02-25
EP3183357A1 (en) 2017-06-28
US20180327789A1 (en) 2018-11-15
EP3183357A4 (en) 2018-07-04
US10934564B2 (en) 2021-03-02

Similar Documents

Publication Publication Date Title
SG11201701278RA (en) Methods for production of oxygenated terpenes
GB2523154B (en) Method of producing graphene
SG11201606673RA (en) Methods for recombinant production of saffron compounds
SG11201701945RA (en) Process for making cyclohexanone
SG11201701764WA (en) Process for making cyclohexanone
SG11201701429SA (en) Process for making cyclohexanone
GB2522719B (en) Method of manufacture
IL248267A0 (en) A process for preparing converted cycloserines
SG11201702271VA (en) A process for the production of oligomerized olefins
GB2527889B (en) Airframe production
GB201506074D0 (en) Object production
EP3180296A4 (en) Methods of producing alkylfurans
PT3131729T (pt) Molde tandem para a produção de peças moldadas por injecção a partir de plástico
GB2522716B (en) Method of manufacture
GB201416909D0 (en) Method of forming concentrated solution
ZA201704196B (en) Method for the production of praziquantel
IL247443B (en) Process for the preparation of 5-fluorotryptophol
GB2531092B (en) Production of airframe components
EP3181545C0 (en) PROCESS FOR PREPARING OSPEMIFENE
GB2532451B (en) Object production
GB201419454D0 (en) New process
SG11201610277SA (en) Process for producing benzene and lpg2
GB201406777D0 (en) Production of drops
GB201407183D0 (en) Production of airframe components
GB201416951D0 (en) Method of synthesis