SG11201701122XA - Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods - Google Patents

Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods

Info

Publication number
SG11201701122XA
SG11201701122XA SG11201701122XA SG11201701122XA SG11201701122XA SG 11201701122X A SG11201701122X A SG 11201701122XA SG 11201701122X A SG11201701122X A SG 11201701122XA SG 11201701122X A SG11201701122X A SG 11201701122XA SG 11201701122X A SG11201701122X A SG 11201701122XA
Authority
SG
Singapore
Prior art keywords
timp
variants
compositions
methods
tissue inhibitor
Prior art date
Application number
SG11201701122XA
Other languages
English (en)
Inventor
Jason C O'neill
Randal R Ketchem
Taeweon Lee
Vishnu Chintalgattu
Jennitte Leann Stevens
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54035361&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201701122X(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of SG11201701122XA publication Critical patent/SG11201701122XA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
SG11201701122XA 2014-08-27 2015-08-26 Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods SG11201701122XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462042574P 2014-08-27 2014-08-27
PCT/US2015/046992 WO2016033212A1 (en) 2014-08-27 2015-08-26 Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods

Publications (1)

Publication Number Publication Date
SG11201701122XA true SG11201701122XA (en) 2017-03-30

Family

ID=54035361

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201701122XA SG11201701122XA (en) 2014-08-27 2015-08-26 Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods

Country Status (18)

Country Link
US (2) US11149078B2 (ru)
EP (2) EP3575316A1 (ru)
JP (3) JP6672257B2 (ru)
KR (1) KR20170042301A (ru)
CN (1) CN107001445B (ru)
AR (1) AR101942A1 (ru)
AU (2) AU2015306608B2 (ru)
BR (1) BR112017003889A2 (ru)
CA (1) CA2956726C (ru)
CL (1) CL2017000440A1 (ru)
EA (1) EA201790470A1 (ru)
ES (1) ES2746264T3 (ru)
IL (1) IL249947B (ru)
MX (1) MX2017002466A (ru)
SG (1) SG11201701122XA (ru)
TW (1) TW201613961A (ru)
UY (1) UY36280A (ru)
WO (1) WO2016033212A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202124443A (zh) * 2019-09-16 2021-07-01 瑞士商諾華公司 高親和力的、配位基阻斷性、人源化的抗T細胞免疫球蛋白結構域和黏蛋白結構域3(TIM-3)IgG4抗體用於治療骨髓纖維化之用途

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JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4740461A (en) 1983-12-27 1988-04-26 Genetics Institute, Inc. Vectors and methods for transformation of eucaryotic cells
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
DE3675588D1 (de) 1985-06-19 1990-12-20 Ajinomoto Kk Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
JPS63502716A (ja) 1986-03-07 1988-10-13 マサチューセッツ・インステチュート・オブ・テクノロジー 糖タンパク安定性の強化方法
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
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US5011912A (en) 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
WO1995005478A1 (en) * 1993-08-12 1995-02-23 The Regents Of The University Of California Human timp-3
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JPH09235300A (ja) * 1996-02-29 1997-09-09 Fuji Yakuhin Kogyo Kk ヒトｔｉｍｐ−３及び抗ヒトｔｉｍｐ−３モノクローナル抗体並びにその用途
US20030191056A1 (en) 2002-04-04 2003-10-09 Kenneth Walker Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
US7183256B2 (en) 2003-03-21 2007-02-27 Cleveland Clinic Foundation TIMP3 as VEGF inhibitor
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CA2934472A1 (en) * 2014-01-09 2015-07-16 Alpha-O Peptides Ag Flagellin-containing protein nanoparticles as a vaccine platform

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CA2956726A1 (en) 2016-03-03
AU2020203749B2 (en) 2021-11-18
EP3186276A1 (en) 2017-07-05
IL249947A0 (en) 2017-03-30
AU2015306608B2 (en) 2020-03-05
AU2015306608A1 (en) 2017-02-02
BR112017003889A2 (pt) 2018-02-27
EP3186276B1 (en) 2019-07-10
AR101942A1 (es) 2017-01-25
US11149078B2 (en) 2021-10-19
WO2016033212A1 (en) 2016-03-03
US20180030116A1 (en) 2018-02-01
JP2020108383A (ja) 2020-07-16
KR20170042301A (ko) 2017-04-18
JP2017532004A (ja) 2017-11-02
EA201790470A1 (ru) 2017-07-31
CN107001445A (zh) 2017-08-01
AU2020203749A1 (en) 2020-06-25
ES2746264T3 (es) 2020-03-05
EP3575316A1 (en) 2019-12-04
MX2017002466A (es) 2017-05-15
US20220089689A1 (en) 2022-03-24
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TW201613961A (en) 2016-04-16
UY36280A (es) 2016-04-01
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JP7075426B2 (ja) 2022-05-25
IL249947B (en) 2021-04-29
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