CL2017000440A1 - Variantes de inhibidor de tejido de metaloproteinasa tipo tres (timp-3), composiciones y metodos - Google Patents

Variantes de inhibidor de tejido de metaloproteinasa tipo tres (timp-3), composiciones y metodos

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Publication number
CL2017000440A1
CL2017000440A1 CL2017000440A CL2017000440A CL2017000440A1 CL 2017000440 A1 CL2017000440 A1 CL 2017000440A1 CL 2017000440 A CL2017000440 A CL 2017000440A CL 2017000440 A CL2017000440 A CL 2017000440A CL 2017000440 A1 CL2017000440 A1 CL 2017000440A1
Authority
CL
Chile
Prior art keywords
timp
methods
variants
compositions
type
Prior art date
Application number
CL2017000440A
Other languages
English (en)
Inventor
Jason C O'neill
Randal R Ketchem
Taeweon Lee
Vishnu Chintalgattu
Jennitte Leann Stevens
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54035361&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2017000440(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of CL2017000440A1 publication Critical patent/CL2017000440A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
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    • A—HUMAN NECESSITIES
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    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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Abstract

<p>SE DESCRIBEN MUTEÍNAS, VARIANTES Y DERIVADOS DE TIMP-3, ÁCIDOS NUCLEICOS QUE LOS CODIFICAN Y MÉTODOS PARA ELABORARLOS Y UTILIZARLOS.</p>
CL2017000440A 2014-08-27 2017-02-24 Variantes de inhibidor de tejido de metaloproteinasa tipo tres (timp-3), composiciones y metodos CL2017000440A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462042574P 2014-08-27 2014-08-27

Publications (1)

Publication Number Publication Date
CL2017000440A1 true CL2017000440A1 (es) 2017-10-13

Family

ID=54035361

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017000440A CL2017000440A1 (es) 2014-08-27 2017-02-24 Variantes de inhibidor de tejido de metaloproteinasa tipo tres (timp-3), composiciones y metodos

Country Status (18)

Country Link
US (2) US11149078B2 (es)
EP (2) EP3575316A1 (es)
JP (3) JP6672257B2 (es)
KR (1) KR20170042301A (es)
CN (1) CN107001445B (es)
AR (1) AR101942A1 (es)
AU (2) AU2015306608B2 (es)
BR (1) BR112017003889A2 (es)
CA (1) CA2956726C (es)
CL (1) CL2017000440A1 (es)
EA (1) EA201790470A1 (es)
ES (1) ES2746264T3 (es)
IL (1) IL249947B (es)
MX (1) MX2017002466A (es)
SG (1) SG11201701122XA (es)
TW (1) TW201613961A (es)
UY (1) UY36280A (es)
WO (1) WO2016033212A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022548627A (ja) * 2019-09-16 2022-11-21 ノバルティス アーゲー 骨髄線維症の治療のための、高親和性のリガンドを遮断するヒト化抗ｔ細胞免疫グロブリンドメイン及びムチンドメイン３（ｔｉｍ－３）ｉｇｇ４抗体の使用

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JPH09235300A (ja) * 1996-02-29 1997-09-09 Fuji Yakuhin Kogyo Kk ヒトｔｉｍｐ−３及び抗ヒトｔｉｍｐ−３モノクローナル抗体並びにその用途
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Also Published As

Publication number Publication date
TW201613961A (en) 2016-04-16
US20220089689A1 (en) 2022-03-24
UY36280A (es) 2016-04-01
CA2956726A1 (en) 2016-03-03
AU2020203749B2 (en) 2021-11-18
WO2016033212A1 (en) 2016-03-03
KR20170042301A (ko) 2017-04-18
AU2015306608A1 (en) 2017-02-02
EP3575316A1 (en) 2019-12-04
BR112017003889A2 (pt) 2018-02-27
IL249947B (en) 2021-04-29
JP2022058365A (ja) 2022-04-12
JP6672257B2 (ja) 2020-03-25
EP3186276A1 (en) 2017-07-05
AU2015306608B2 (en) 2020-03-05
SG11201701122XA (en) 2017-03-30
JP2017532004A (ja) 2017-11-02
US11149078B2 (en) 2021-10-19
MX2017002466A (es) 2017-05-15
EP3186276B1 (en) 2019-07-10
US20180030116A1 (en) 2018-02-01
JP7075426B2 (ja) 2022-05-25
JP2020108383A (ja) 2020-07-16
AU2020203749A1 (en) 2020-06-25
IL249947A0 (en) 2017-03-30
CN107001445B (zh) 2022-06-24
EA201790470A1 (ru) 2017-07-31
CA2956726C (en) 2023-06-06
CN107001445A (zh) 2017-08-01
ES2746264T3 (es) 2020-03-05
AR101942A1 (es) 2017-01-25

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