SG11201608710TA - Anti-enterovirus 71 thiadiazolidine derivative - Google Patents
Anti-enterovirus 71 thiadiazolidine derivativeInfo
- Publication number
- SG11201608710TA SG11201608710TA SG11201608710TA SG11201608710TA SG11201608710TA SG 11201608710T A SG11201608710T A SG 11201608710TA SG 11201608710T A SG11201608710T A SG 11201608710TA SG 11201608710T A SG11201608710T A SG 11201608710TA SG 11201608710T A SG11201608710T A SG 11201608710TA
- Authority
- SG
- Singapore
- Prior art keywords
- enterovirus
- thiadiazolidine
- derivative
- thiadiazolidine derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410176161 | 2014-04-28 | ||
| CN201410543064.6A CN105085512A (zh) | 2014-04-28 | 2014-10-14 | 抗肠病毒71噻二唑烷衍生物 |
| CN201510182757 | 2015-04-16 | ||
| PCT/CN2015/077043 WO2015165340A1 (zh) | 2014-04-28 | 2015-04-21 | 抗肠病毒71噻二唑烷衍生物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201608710TA true SG11201608710TA (en) | 2016-11-29 |
Family
ID=56755307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201608710TA SG11201608710TA (en) | 2014-04-28 | 2015-04-21 | Anti-enterovirus 71 thiadiazolidine derivative |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9988361B2 (zh) |
| EP (1) | EP3138840B1 (zh) |
| JP (1) | JP6389531B2 (zh) |
| KR (2) | KR20160147010A (zh) |
| CN (1) | CN106661009B (zh) |
| DK (1) | DK3138840T3 (zh) |
| ES (1) | ES2841418T3 (zh) |
| MY (1) | MY176508A (zh) |
| SG (1) | SG11201608710TA (zh) |
| TW (1) | TWI658037B (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6427695B2 (ja) * | 2015-10-26 | 2018-11-21 | ジァンスー カニオン パーマスーティカル カンパニー リミテッド | １，２，５−チアジアゾリジン−１，１−ジオキシドの塩形態、結晶形態及びその調製方法と中間体 |
| CN113940918B (zh) * | 2020-07-17 | 2023-06-02 | 江苏康缘药业股份有限公司 | 一种药物组合物及制备方法 |
| CN114539020B (zh) * | 2022-01-17 | 2023-12-08 | 南京迈诺威医药科技有限公司 | 一种1,5-二溴-3,3-二氟戊烷的制备方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9104136D0 (en) * | 1991-02-27 | 1991-04-17 | Merck Sharp & Dohme | Therapeutic agents |
| DE4107857A1 (de) * | 1991-03-12 | 1992-09-17 | Thomae Gmbh Dr K | Cyclische harnstoffderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| US5852192A (en) * | 1992-03-11 | 1998-12-22 | Dr. Karl Thomae Gmbh | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them |
| SK94393A3 (en) * | 1992-09-11 | 1994-08-10 | Thomae Gmbh Dr K | Cyclic derivatives of urea, process for their production and their pharmaceutical agents with the content of those |
| GB9715816D0 (en) * | 1997-07-25 | 1997-10-01 | Black James Foundation | Histamine H receptor ligands |
| JP2003509430A (ja) * | 1999-09-10 | 2003-03-11 | ノボ ノルディスク アクティーゼルスカブ | プロテインチロシンホスファターゼ（ｐｔｐアーゼ）のモジュレーター |
| FR2803298A1 (fr) * | 1999-12-30 | 2001-07-06 | Adir | Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US6706739B2 (en) * | 2001-08-21 | 2004-03-16 | National Health Research Institute | Imidazolidinone compounds |
| US7129359B2 (en) * | 2002-07-09 | 2006-10-31 | National Health Research Institutes | Imidazolidinone compounds |
| CA2493458A1 (en) * | 2002-07-24 | 2004-01-29 | Ptc Therapeutics, Inc. | Ureido substituted benzoic acid compounds, their use for nonsense suppression and the treatment of diseases caused by such mutations |
| US7259174B2 (en) * | 2004-05-25 | 2007-08-21 | National Health Research Institutes | Imidazolidinone compounds |
| KR20070083484A (ko) * | 2004-07-14 | 2007-08-24 | 피티씨 테라퓨틱스, 인크. | Ｃ형 간염 치료 방법 |
| US8183239B2 (en) * | 2005-10-31 | 2012-05-22 | Janssen Pharmaceutica Nv | Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor |
| CA2627306A1 (en) * | 2005-11-01 | 2007-05-10 | Transtech Pharma, Inc. | Pharmaceutical use of substituted amides |
| KR20110077006A (ko) * | 2006-08-15 | 2011-07-06 | 노파르티스 아게 | 증가된 지질 수준과 관련된 질환의 치료에 적합한 헤테로시클릭 화합물 |
| CN102143962B (zh) * | 2008-07-02 | 2015-03-11 | 爱维艾珂瑟有限公司 | 具有抗病毒特性的化合物 |
| WO2010029048A1 (en) * | 2008-09-09 | 2010-03-18 | Sekmed Srl | 1, 2, 5-thiadiazole derivatives useful as immune potentiators |
| CN102344416B (zh) * | 2010-08-02 | 2015-09-16 | 中国人民解放军军事医学科学院毒物药物研究所 | 哒嗪衍生物及其作为抗小rna病毒感染药物的用途 |
| CN102485717B (zh) * | 2010-12-06 | 2015-12-02 | 中国人民解放军军事医学科学院毒物药物研究所 | 噻唑胺衍生物及其作为抗小rna病毒感染药物的用途 |
| KR101332805B1 (ko) * | 2011-03-31 | 2013-11-27 | 한국화학연구원 | 아다만틸기를 갖는 설파마이드 유도체 및 이의 약제학적으로 허용 가능한 염 |
| GB201402169D0 (en) * | 2014-02-07 | 2014-03-26 | Isis Innovation | Viral inhibitors |
-
2015
- 2015-04-21 US US15/307,710 patent/US9988361B2/en active Active
- 2015-04-21 DK DK15786304.4T patent/DK3138840T3/da active
- 2015-04-21 KR KR1020167033211A patent/KR20160147010A/ko not_active Application Discontinuation
- 2015-04-21 MY MYPI2016703942A patent/MY176508A/en unknown
- 2015-04-21 ES ES15786304T patent/ES2841418T3/es active Active
- 2015-04-21 EP EP15786304.4A patent/EP3138840B1/en active Active
- 2015-04-21 KR KR1020187016595A patent/KR101957178B1/ko active IP Right Grant
- 2015-04-21 CN CN201580011272.4A patent/CN106661009B/zh active Active
- 2015-04-21 JP JP2016565011A patent/JP6389531B2/ja active Active
- 2015-04-21 SG SG11201608710TA patent/SG11201608710TA/en unknown
- 2015-04-27 TW TW104113441A patent/TWI658037B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| US20170066732A1 (en) | 2017-03-09 |
| TW201620885A (zh) | 2016-06-16 |
| KR101957178B1 (ko) | 2019-03-12 |
| KR20180069103A (ko) | 2018-06-22 |
| EP3138840B1 (en) | 2020-09-23 |
| JP2017513914A (ja) | 2017-06-01 |
| TWI658037B (zh) | 2019-05-01 |
| US9988361B2 (en) | 2018-06-05 |
| ES2841418T3 (es) | 2021-07-08 |
| MY176508A (en) | 2020-08-12 |
| DK3138840T3 (da) | 2020-12-21 |
| EP3138840A4 (en) | 2017-12-20 |
| KR20160147010A (ko) | 2016-12-21 |
| JP6389531B2 (ja) | 2018-09-12 |
| CN106661009B (zh) | 2019-11-26 |
| EP3138840A1 (en) | 2017-03-08 |
| CN106661009A (zh) | 2017-05-10 |
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