SG11201605485QA - Synthesis method of 9-allylcamptothecin derivatives - Google Patents

Synthesis method of 9-allylcamptothecin derivatives

Info

Publication number
SG11201605485QA
SG11201605485QA SG11201605485QA SG11201605485QA SG11201605485QA SG 11201605485Q A SG11201605485Q A SG 11201605485QA SG 11201605485Q A SG11201605485Q A SG 11201605485QA SG 11201605485Q A SG11201605485Q A SG 11201605485QA SG 11201605485Q A SG11201605485Q A SG 11201605485QA
Authority
SG
Singapore
Prior art keywords
allylcamptothecin
derivatives
synthesis method
synthesis
allylcamptothecin derivatives
Prior art date
Application number
SG11201605485QA
Other languages
English (en)
Inventor
Lei Jiang
Lei Liu
Lei Li
Original Assignee
Shanghai Haihe Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Haihe Pharmaceutical Co Ltd filed Critical Shanghai Haihe Pharmaceutical Co Ltd
Publication of SG11201605485QA publication Critical patent/SG11201605485QA/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/1616Coordination complexes, e.g. organometallic complexes, immobilised on an inorganic support, e.g. ship-in-a-bottle type catalysts
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/24Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201605485QA 2014-01-15 2014-12-31 Synthesis method of 9-allylcamptothecin derivatives SG11201605485QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201410018451.8A CN104774209B (zh) 2014-01-15 2014-01-15 一种9-烯丙基喜树碱衍生物的合成方法
PCT/CN2014/096002 WO2015106633A1 (zh) 2014-01-15 2014-12-31 一种9-烯丙基喜树碱衍生物的合成方法

Publications (1)

Publication Number Publication Date
SG11201605485QA true SG11201605485QA (en) 2016-08-30

Family

ID=53542388

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201605485QA SG11201605485QA (en) 2014-01-15 2014-12-31 Synthesis method of 9-allylcamptothecin derivatives

Country Status (13)

Country Link
US (1) US9643975B2 (zh)
EP (1) EP3095785B1 (zh)
JP (1) JP6216895B2 (zh)
KR (1) KR101887447B1 (zh)
CN (1) CN104774209B (zh)
AU (1) AU2014378009B2 (zh)
BR (1) BR112016016361A2 (zh)
CA (1) CA2935504C (zh)
HK (1) HK1208220A1 (zh)
MX (1) MX365384B (zh)
RU (1) RU2658017C2 (zh)
SG (1) SG11201605485QA (zh)
WO (1) WO2015106633A1 (zh)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6185319A (ja) * 1984-10-03 1986-04-30 Yakult Honsha Co Ltd 抗腫瘍剤
GB9510716D0 (en) * 1995-05-26 1995-07-19 Pharmacia Spa Substituted camptothecin derivatives and process for their preparation
IT1282673B1 (it) * 1996-02-23 1998-03-31 Ist Naz Stud Cura Dei Tumori Derivati della camptotecina e loro uso come agenti antitumorali
CN100406460C (zh) * 2003-11-10 2008-07-30 中国科学院上海药物研究所 喜树碱的新衍生物、制备方法和用途
CN1587265A (zh) * 2004-07-08 2005-03-02 浙江大学 10-烷氧基喜树碱衍生物及其制备方法与应用
CN101033230B (zh) * 2006-03-10 2010-12-08 中国科学院上海药物研究所 一类喜树碱衍生物及其应用
CN101337966B (zh) * 2007-07-06 2011-05-18 江苏恒瑞医药股份有限公司 一种制备高纯度伊立替康的方法
AU2009252303B2 (en) 2008-05-29 2013-04-04 Microbiopharm Japan Co., Ltd. Production method for camptothecin derivative
CN101880285B (zh) * 2010-06-24 2012-07-04 华东师范大学 一种烯丙基取代喜树碱化合物的合成方法
TWI417248B (zh) 2011-12-23 2013-12-01 Ind Tech Res Inst 熱電材料與其製造方法、以及包含其熱電模組
CN102627653B (zh) * 2012-03-20 2014-10-29 南京臣功制药股份有限公司 盐酸伊立替康的制备方法
WO2013179144A2 (en) * 2012-06-01 2013-12-05 Oxalys Pharmaceuticals Chemical suppressors of neurotoxicity in synucleinopathic diseases

Also Published As

Publication number Publication date
CA2935504A1 (en) 2015-07-23
MX365384B (es) 2019-05-31
BR112016016361A2 (pt) 2017-08-08
HK1208220A1 (zh) 2016-02-26
CA2935504C (en) 2018-10-23
EP3095785B1 (en) 2018-02-07
EP3095785A1 (en) 2016-11-23
WO2015106633A1 (zh) 2015-07-23
CN104774209B (zh) 2018-06-19
RU2658017C2 (ru) 2018-06-19
AU2014378009A1 (en) 2016-07-21
MX2016009179A (es) 2016-09-09
KR101887447B1 (ko) 2018-08-10
AU2014378009B2 (en) 2017-09-07
US20160340364A1 (en) 2016-11-24
JP6216895B2 (ja) 2017-10-18
JP2017507170A (ja) 2017-03-16
KR20160144962A (ko) 2016-12-19
RU2016133470A (ru) 2018-02-20
EP3095785A4 (en) 2016-11-23
US9643975B2 (en) 2017-05-09
CN104774209A (zh) 2015-07-15

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