SG11201605485QA - Synthesis method of 9-allylcamptothecin derivatives - Google Patents

Synthesis method of 9-allylcamptothecin derivatives

Info

Publication number
SG11201605485QA
SG11201605485QA SG11201605485QA SG11201605485QA SG11201605485QA SG 11201605485Q A SG11201605485Q A SG 11201605485QA SG 11201605485Q A SG11201605485Q A SG 11201605485QA SG 11201605485Q A SG11201605485Q A SG 11201605485QA SG 11201605485Q A SG11201605485Q A SG 11201605485QA
Authority
SG
Singapore
Prior art keywords
allylcamptothecin
derivatives
synthesis method
synthesis
allylcamptothecin derivatives
Prior art date
Application number
SG11201605485QA
Inventor
Lei Jiang
Lei Liu
Lei Li
Original Assignee
Shanghai Haihe Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Haihe Pharmaceutical Co Ltd filed Critical Shanghai Haihe Pharmaceutical Co Ltd
Publication of SG11201605485QA publication Critical patent/SG11201605485QA/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/1616Coordination complexes, e.g. organometallic complexes, immobilised on an inorganic support, e.g. ship-in-a-bottle type catalysts
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/24Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
SG11201605485QA 2014-01-15 2014-12-31 Synthesis method of 9-allylcamptothecin derivatives SG11201605485QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201410018451.8A CN104774209B (en) 2014-01-15 2014-01-15 A kind of synthetic method of 9- allyl-camptothecines derivative
PCT/CN2014/096002 WO2015106633A1 (en) 2014-01-15 2014-12-31 Synthesis method of 9-allylcamptothecin derivatives

Publications (1)

Publication Number Publication Date
SG11201605485QA true SG11201605485QA (en) 2016-08-30

Family

ID=53542388

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201605485QA SG11201605485QA (en) 2014-01-15 2014-12-31 Synthesis method of 9-allylcamptothecin derivatives

Country Status (13)

Country Link
US (1) US9643975B2 (en)
EP (1) EP3095785B1 (en)
JP (1) JP6216895B2 (en)
KR (1) KR101887447B1 (en)
CN (1) CN104774209B (en)
AU (1) AU2014378009B2 (en)
BR (1) BR112016016361A2 (en)
CA (1) CA2935504C (en)
HK (1) HK1208220A1 (en)
MX (1) MX365384B (en)
RU (1) RU2658017C2 (en)
SG (1) SG11201605485QA (en)
WO (1) WO2015106633A1 (en)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6185319A (en) * 1984-10-03 1986-04-30 Yakult Honsha Co Ltd Antineoplastic agent
GB9510716D0 (en) * 1995-05-26 1995-07-19 Pharmacia Spa Substituted camptothecin derivatives and process for their preparation
IT1282673B1 (en) * 1996-02-23 1998-03-31 Ist Naz Stud Cura Dei Tumori CAMPTOTECIN DERIVATIVES AND THEIR USE AS ANTI-CANCER AGENTS
CN100406460C (en) * 2003-11-10 2008-07-30 中国科学院上海药物研究所 Novel derivative of camptothecine, preparing method and use
CN1587265A (en) * 2004-07-08 2005-03-02 浙江大学 10-alkoxy camptothecine derivative and its preparing method and use
CN101033230B (en) * 2006-03-10 2010-12-08 中国科学院上海药物研究所 Cmptothecine derivative and application thereof
CN101337966B (en) * 2007-07-06 2011-05-18 江苏恒瑞医药股份有限公司 Method for preparing high-purity irinotecan
AU2009252303B2 (en) 2008-05-29 2013-04-04 Microbiopharm Japan Co., Ltd. Production method for camptothecin derivative
CN101880285B (en) * 2010-06-24 2012-07-04 华东师范大学 Method for synthetizing allyl-substituted camptothecin compound
TWI417248B (en) 2011-12-23 2013-12-01 Ind Tech Res Inst Thermoelectric material, method for fabricating the same, and thermoelectric module employing the same
CN102627653B (en) * 2012-03-20 2014-10-29 南京臣功制药股份有限公司 Preparation method of irinotecan hydrochloride
WO2013179144A2 (en) * 2012-06-01 2013-12-05 Oxalys Pharmaceuticals Chemical suppressors of neurotoxicity in synucleinopathic diseases

Also Published As

Publication number Publication date
CA2935504A1 (en) 2015-07-23
MX365384B (en) 2019-05-31
BR112016016361A2 (en) 2017-08-08
HK1208220A1 (en) 2016-02-26
CA2935504C (en) 2018-10-23
EP3095785B1 (en) 2018-02-07
EP3095785A1 (en) 2016-11-23
WO2015106633A1 (en) 2015-07-23
CN104774209B (en) 2018-06-19
RU2658017C2 (en) 2018-06-19
AU2014378009A1 (en) 2016-07-21
MX2016009179A (en) 2016-09-09
KR101887447B1 (en) 2018-08-10
AU2014378009B2 (en) 2017-09-07
US20160340364A1 (en) 2016-11-24
JP6216895B2 (en) 2017-10-18
JP2017507170A (en) 2017-03-16
KR20160144962A (en) 2016-12-19
RU2016133470A (en) 2018-02-20
EP3095785A4 (en) 2016-11-23
US9643975B2 (en) 2017-05-09
CN104774209A (en) 2015-07-15

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