SG11201605014YA - Antibacterial 1h-indazole and 1h-indole derivatives - Google Patents
Antibacterial 1h-indazole and 1h-indole derivativesInfo
- Publication number
- SG11201605014YA SG11201605014YA SG11201605014YA SG11201605014YA SG11201605014YA SG 11201605014Y A SG11201605014Y A SG 11201605014YA SG 11201605014Y A SG11201605014Y A SG 11201605014YA SG 11201605014Y A SG11201605014Y A SG 11201605014YA SG 11201605014Y A SG11201605014Y A SG 11201605014YA
- Authority
- SG
- Singapore
- Prior art keywords
- indazole
- antibacterial
- indole derivatives
- indole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13198338 | 2013-12-19 | ||
| PCT/EP2014/078384 WO2015091741A1 (en) | 2013-12-19 | 2014-12-18 | Antibacterial 1h-indazole and 1h-indole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201605014YA true SG11201605014YA (en) | 2016-07-28 |
Family
ID=49880464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201605014YA SG11201605014YA (en) | 2013-12-19 | 2014-12-18 | Antibacterial 1h-indazole and 1h-indole derivatives |
Country Status (22)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR097617A1 (es) | 2013-09-13 | 2016-04-06 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos del 2h-indazol |
| AR099612A1 (es) | 2014-03-04 | 2016-08-03 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona |
| CN106458931A (zh) | 2014-05-16 | 2017-02-22 | 埃科特莱茵药品有限公司 | 抗菌的喹唑啉‑4(3h)‑酮衍生物 |
| SG11201703992YA (en) | 2014-11-19 | 2017-06-29 | Actelion Pharmaceuticals Ltd | Antibacterial benzothiazole derivatives |
| AR105646A1 (es) | 2015-08-11 | 2017-10-25 | Actelion Pharmaceuticals Ltd | Agentes antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituida |
| EA201890600A1 (ru) * | 2015-08-28 | 2018-09-28 | Идорсиа Фармасьютиклз Лтд | Антибактериальные аннелированные производные пирролидин-2-она |
| AR105848A1 (es) * | 2015-08-31 | 2017-11-15 | Actelion Pharmaceuticals Ltd | Derivados heterocíclicos antibacterianos |
| AR105889A1 (es) | 2015-09-03 | 2017-11-22 | Actelion Pharmaceuticals Ltd | Compuestos antibacterianos 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituidos |
| US20190315731A1 (en) * | 2016-05-17 | 2019-10-17 | Jörg Volker | 6-(buta-1,3-diyn-1-yl)benzo[d]thiazole derivatives |
| TW201906819A (zh) | 2017-05-25 | 2019-02-16 | 日商大正製藥股份有限公司 | 新穎之咪唑衍生物 |
| WO2019086452A1 (en) * | 2017-10-31 | 2019-05-09 | Idorsia Pharmaceuticals Ltd | Antibacterial heteroaromatic compounds |
| CN113666860B (zh) * | 2020-05-14 | 2024-03-15 | 鲁南制药集团股份有限公司 | 一种7-乙基色醇的制备方法 |
| CN119014415B (zh) * | 2024-08-19 | 2025-09-05 | 浙江大学 | 1-甲氧基吲哚在驱避和/或杀灭害虫中的应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DOP2003000613A (es) | 2002-03-13 | 2003-09-30 | Array Biopharma Inc | Derivados de bencimidazol n3 alquilado como inhibidores de mek (n3 alkylated benzimidazole derivatives as mek inhibitors) |
| DE102004017930A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
| CN101389335A (zh) | 2004-10-18 | 2009-03-18 | 安姆根有限公司 | 噻二唑化合物和使用方法 |
| MX2007011483A (es) | 2005-03-23 | 2007-10-12 | Hoffmann La Roche | Derivados de acetilenil-pirazolo-pirimidina como antagonistas de glutamato metabotropico 2. |
| CA2691987C (en) | 2007-06-12 | 2016-08-16 | Achaogen, Inc. | Antibacterial agents |
| EP2432468A2 (en) | 2009-05-20 | 2012-03-28 | Ardea Biosciences, Inc. | Methods of modulating uric acid levels |
| EP2488489A2 (en) * | 2009-10-13 | 2012-08-22 | Pfizer Inc. | C-linked hydroxamic acid derivatives useful as antibacterial agents |
| SI2512474T1 (sl) | 2009-12-16 | 2014-12-31 | Pfizer Inc. | N-vezani derivati hidroksamske kisline, uporabni kot protibakterijska sredstva |
| GB2483736B (en) | 2010-09-16 | 2012-08-29 | Aragon Pharmaceuticals Inc | Estrogen receptor modulators and uses thereof |
| EA201390626A1 (ru) | 2010-11-10 | 2013-12-30 | Эйкеоджен, Инк. | Производные гидроксамовой кислоты и применение указанных производных в лечении бактериальных инфекций |
| US8853213B2 (en) | 2011-01-03 | 2014-10-07 | Hanmi Pharm. Co., Ltd | Bicyclic compound for modulating G protein-coupled receptors |
| AP3336A (en) * | 2011-03-07 | 2015-07-31 | Pfizer | Fluoro-pyridinone derivatives useful as antibacterial agents |
| CN103717582B (zh) | 2011-04-08 | 2015-09-30 | 辉瑞大药厂 | 用作抗菌剂的异*唑衍生物 |
| KR20130140164A (ko) * | 2011-04-08 | 2013-12-23 | 화이자 인코포레이티드 | 항박테리아제로서 유용한 이미다졸, 피라졸 및 트라이아졸 유도체 |
| EP2847162A1 (en) | 2012-05-09 | 2015-03-18 | Achaogen, Inc. | Antibacterial agents |
| WO2013170165A1 (en) | 2012-05-10 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| AR097617A1 (es) | 2013-09-13 | 2016-04-06 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos del 2h-indazol |
| AR099612A1 (es) | 2014-03-04 | 2016-08-03 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona |
| CN106458931A (zh) | 2014-05-16 | 2017-02-22 | 埃科特莱茵药品有限公司 | 抗菌的喹唑啉‑4(3h)‑酮衍生物 |
-
2014
- 2014-12-18 CN CN201480067976.9A patent/CN105829288B/zh not_active Expired - Fee Related
- 2014-12-18 BR BR112016014115A patent/BR112016014115A8/pt not_active Application Discontinuation
- 2014-12-18 JP JP2016541300A patent/JP6407288B2/ja not_active Expired - Fee Related
- 2014-12-18 MA MA39189A patent/MA39189A1/fr unknown
- 2014-12-18 KR KR1020167019669A patent/KR20160098503A/ko not_active Ceased
- 2014-12-18 ES ES14812752.5T patent/ES2666130T3/es active Active
- 2014-12-18 SG SG11201605014YA patent/SG11201605014YA/en unknown
- 2014-12-18 TR TR2018/07881T patent/TR201807881T4/tr unknown
- 2014-12-18 WO PCT/EP2014/078384 patent/WO2015091741A1/en active Application Filing
- 2014-12-18 AU AU2014368619A patent/AU2014368619B2/en not_active Ceased
- 2014-12-18 US US15/106,790 patent/US9624206B2/en not_active Expired - Fee Related
- 2014-12-18 MX MX2016007991A patent/MX360983B/es active IP Right Grant
- 2014-12-18 CA CA2933604A patent/CA2933604A1/en not_active Abandoned
- 2014-12-18 PL PL14812752T patent/PL3083567T3/pl unknown
- 2014-12-18 EP EP14812752.5A patent/EP3083567B1/en not_active Not-in-force
- 2014-12-18 TW TW103144395A patent/TW201609641A/zh unknown
- 2014-12-18 AR ARP140104742A patent/AR100032A1/es unknown
- 2014-12-18 EA EA201600475A patent/EA030730B1/ru not_active IP Right Cessation
-
2016
- 2016-06-09 PH PH12016501102A patent/PH12016501102A1/en unknown
- 2016-06-14 IL IL246201A patent/IL246201A0/en unknown
- 2016-06-16 CL CL2016001524A patent/CL2016001524A1/es unknown
- 2016-07-18 ZA ZA2016/04968A patent/ZA201604968B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US9624206B2 (en) | 2017-04-18 |
| WO2015091741A1 (en) | 2015-06-25 |
| EA030730B1 (ru) | 2018-09-28 |
| JP2017500336A (ja) | 2017-01-05 |
| TR201807881T4 (tr) | 2018-06-21 |
| IL246201A0 (en) | 2016-08-02 |
| MA39189A1 (fr) | 2017-06-30 |
| PL3083567T3 (pl) | 2018-08-31 |
| US20170029411A1 (en) | 2017-02-02 |
| BR112016014115A2 (enrdf_load_html_response) | 2017-08-08 |
| MX2016007991A (es) | 2016-10-07 |
| AU2014368619A1 (en) | 2016-07-28 |
| TW201609641A (zh) | 2016-03-16 |
| ZA201604968B (en) | 2018-11-28 |
| EP3083567B1 (en) | 2018-03-07 |
| CA2933604A1 (en) | 2015-06-25 |
| EP3083567A1 (en) | 2016-10-26 |
| CN105829288B (zh) | 2019-01-15 |
| CN105829288A (zh) | 2016-08-03 |
| EA201600475A1 (ru) | 2016-11-30 |
| AR100032A1 (es) | 2016-09-07 |
| AU2014368619B2 (en) | 2018-11-22 |
| MX360983B (es) | 2018-11-22 |
| KR20160098503A (ko) | 2016-08-18 |
| BR112016014115A8 (pt) | 2017-12-26 |
| PH12016501102A1 (en) | 2016-07-11 |
| CL2016001524A1 (es) | 2017-01-27 |
| ES2666130T3 (es) | 2018-05-03 |
| JP6407288B2 (ja) | 2018-10-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA201604968B (en) | Antibacterial 1h-indazole and 1h-indole derivatives | |
| IL246221B (en) | Endazoles and their uses | |
| IL240863B (en) | Amatoxin derivatives | |
| IL240527B (en) | Composition of dentures and denture system | |
| SG11201506100XA (en) | Pyridazinone-amides derivatives | |
| IL241374A0 (en) | History of benzimidazole and their use | |
| IL244500B (en) | History of h2–indazole antibacterials | |
| IL244214B (en) | Thienopiperidine derivative and its use | |
| SG11201600743WA (en) | Oxoquinazolinyl-butanamide derivatives | |
| SG11201506713TA (en) | 2-acylaminothiazole derivative and salt thereof | |
| SG11201605189YA (en) | Imidazopyrazinone derivatives | |
| SG11201510584WA (en) | Phthalazine derivatives | |
| HK1230585A1 (en) | Antibacterial 1h-indazole and 1h-indole derivatives | |
| GB201301393D0 (en) | Kiddibidet and pottibidet | |
| GB201309248D0 (en) | Compounds and combinations |