SG11201602796QA - Method for purification of retinal pigment epithelial cells - Google Patents
Method for purification of retinal pigment epithelial cellsInfo
- Publication number
- SG11201602796QA SG11201602796QA SG11201602796QA SG11201602796QA SG11201602796QA SG 11201602796Q A SG11201602796Q A SG 11201602796QA SG 11201602796Q A SG11201602796Q A SG 11201602796QA SG 11201602796Q A SG11201602796Q A SG 11201602796QA SG 11201602796Q A SG11201602796Q A SG 11201602796QA
- Authority
- SG
- Singapore
- Prior art keywords
- purification
- epithelial cells
- retinal pigment
- pigment epithelial
- retinal
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases (EC 2.)
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Developmental Biology & Embryology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013212345 | 2013-10-09 | ||
| PCT/JP2014/077112 WO2015053376A1 (ja) | 2013-10-09 | 2014-10-09 | 網膜色素上皮細胞の純化方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201602796QA true SG11201602796QA (en) | 2016-05-30 |
Family
ID=52813190
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201602796QA SG11201602796QA (en) | 2013-10-09 | 2014-10-09 | Method for purification of retinal pigment epithelial cells |
| SG10201802877WA SG10201802877WA (en) | 2013-10-09 | 2014-10-09 | Method of producing retinal pigment epithelial cell |
| SG11201602734SA SG11201602734SA (en) | 2013-10-09 | 2014-10-09 | Method of producing retinal pigment epithelial cell |
| SG10201802879PA SG10201802879PA (en) | 2013-10-09 | 2014-10-09 | Method for purification of retinal pigment epithelial cells |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201802877WA SG10201802877WA (en) | 2013-10-09 | 2014-10-09 | Method of producing retinal pigment epithelial cell |
| SG11201602734SA SG11201602734SA (en) | 2013-10-09 | 2014-10-09 | Method of producing retinal pigment epithelial cell |
| SG10201802879PA SG10201802879PA (en) | 2013-10-09 | 2014-10-09 | Method for purification of retinal pigment epithelial cells |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20160237403A1 (de) |
| EP (2) | EP3056564B1 (de) |
| JP (4) | JP6518878B2 (de) |
| KR (2) | KR102245015B1 (de) |
| CN (2) | CN105849254A (de) |
| AU (2) | AU2014332856B2 (de) |
| BR (1) | BR112016007833B1 (de) |
| CA (2) | CA2926721C (de) |
| SG (4) | SG11201602796QA (de) |
| WO (2) | WO2015053375A1 (de) |
| ZA (2) | ZA201603054B (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011063005A2 (en) | 2009-11-17 | 2011-05-26 | Advanced Cell Technology, Inc. | Methods of producing human rpe cells and pharmaceutical preparations of human rpe cells |
| JP6518878B2 (ja) | 2013-10-09 | 2019-05-29 | 株式会社ヘリオス | 網膜色素上皮細胞の製造方法 |
| CN105814195A (zh) | 2013-11-27 | 2016-07-27 | 京都府公立大学法人 | 层粘连蛋白应用于角膜内皮细胞培养 |
| MY191740A (en) | 2014-10-24 | 2022-07-13 | Sumitomo Chemical Co | Production method for nerve tissue |
| WO2016063986A1 (ja) | 2014-10-24 | 2016-04-28 | 大日本住友製薬株式会社 | 網膜組織の製造方法 |
| CN113559246A (zh) | 2014-10-31 | 2021-10-29 | 京都府公立大学法人 | 使用层粘连蛋白的新的角膜的治疗 |
| US11918630B2 (en) * | 2014-10-31 | 2024-03-05 | Kyoto Prefectural Public University Corporation | Treatment of retina and nerve using laminin |
| CN105013010B (zh) * | 2015-07-07 | 2018-01-12 | 中山大学中山眼科中心 | 一种辅助iPS‑RPE移植的层粘连蛋白膜 |
| WO2017043605A1 (ja) | 2015-09-08 | 2017-03-16 | 大日本住友製薬株式会社 | 網膜色素上皮細胞の製造方法 |
| EP3447129B1 (de) * | 2016-04-22 | 2022-07-20 | Sumitomo Pharma Co., Ltd. | Verfahren zur herstellung von retinagewebe |
| US11618883B2 (en) | 2017-03-08 | 2023-04-04 | Sumitomo Pharma Co., Ltd. | Method for producing retinal pigment epithelial cells |
| JP7150281B2 (ja) * | 2017-07-20 | 2022-10-11 | 国立研究開発法人理化学研究所 | 連続的な上皮を含む網膜組織の成熟化方法 |
| AU2018330694A1 (en) | 2017-09-08 | 2020-03-19 | Riken | Cell aggregate including retinal tissue and production method therefor |
| CN108642014B (zh) * | 2018-05-17 | 2019-10-08 | 山东兴瑞生物科技有限公司 | 利用自体免疫细胞制备视网膜色素上皮细胞薄片的方法 |
| FI3810758T3 (sv) * | 2018-06-20 | 2023-10-11 | Biolamina Ab | Förfaranden och sammansättningar för framställning av retinala pigmentepitelceller |
| JPWO2020204149A1 (de) | 2019-03-29 | 2020-10-08 | ||
| CA3137528A1 (en) | 2019-04-26 | 2020-10-29 | Riken | Composite including neural retina, retinal pigment epithelial cells, and hydrogel, and method for producing same |
| CN114981417A (zh) * | 2019-10-30 | 2022-08-30 | 安斯泰来再生医药协会 | 生产视网膜色素上皮细胞的方法 |
| CN115551998A (zh) | 2020-05-26 | 2022-12-30 | 希里欧斯株式会社 | 低免疫原性细胞 |
| JPWO2022054924A1 (de) | 2020-09-11 | 2022-03-17 | ||
| JPWO2022191216A1 (de) | 2021-03-09 | 2022-09-15 | ||
| CN115261301A (zh) * | 2021-04-30 | 2022-11-01 | 深圳华大生命科学研究院 | 一种视网膜色素上皮细胞体外诱导及培养方法 |
| AU2022266430A1 (en) | 2021-04-30 | 2023-12-14 | Riken | Cord-like aggregates of retinal pigment epithelial cells, device and production method for producing same, and therapeutic agent comprising said cord-like aggregates |
| CA3238664A1 (en) | 2021-11-19 | 2023-05-25 | Riken | Production method for sheet-like retinal tissue |
| CN115418343A (zh) * | 2022-10-28 | 2022-12-02 | 深圳市俊元生物科技有限公司 | 从人视网膜色素上皮细胞中提取多能干细胞的方法 |
| CN116769713B (zh) * | 2023-08-14 | 2023-10-27 | 四川大学华西医院 | 一种视网膜色素上皮细胞的制备方法 |
| CN117625536B (zh) * | 2024-01-26 | 2024-04-30 | 中国人民解放军总医院第三医学中心 | 一种人视网膜色素上皮细胞的纯化、培养方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8492147B2 (en) | 2004-06-18 | 2013-07-23 | Riken | Method of inducing the differentiation of embryonic stem cells into nerve by serum-free suspension culture |
| US9057052B2 (en) | 2005-10-21 | 2015-06-16 | Kaneka Corporation | Stem cell separating material and method of separation |
| EP2128244A4 (de) * | 2007-01-18 | 2012-05-09 | Riken | Verfahren zur induktion/differenzierung zu einer photorezeptorzelle |
| EP2554661B2 (de) * | 2007-04-18 | 2018-02-21 | Hadasit Medical Research Services & Development Limited | Aus Stammzellen erhaltene retinale Pigmentepithelzellen |
| JP5590646B2 (ja) | 2009-10-08 | 2014-09-17 | 国立大学法人大阪大学 | ヒト多能性幹細胞用培養基材およびその利用 |
| JP2012080821A (ja) | 2010-10-12 | 2012-04-26 | Univ Of Tsukuba | 血液中の有核細胞成分濃縮方法 |
| WO2012115244A1 (ja) | 2011-02-25 | 2012-08-30 | 独立行政法人理化学研究所 | 網膜色素上皮細胞シートの製造方法 |
| JP6169972B2 (ja) | 2011-11-09 | 2017-07-26 | 株式会社カネカ | 幹細胞分離方法 |
| US9850463B2 (en) | 2012-02-01 | 2017-12-26 | The Regents Of The University Of California | Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation |
| US10519422B2 (en) | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
| JP2013212345A (ja) | 2012-04-03 | 2013-10-17 | Kurashiki Seni Kako Kk | カーテン用不織布およびその製造方法 |
| JP6518878B2 (ja) | 2013-10-09 | 2019-05-29 | 株式会社ヘリオス | 網膜色素上皮細胞の製造方法 |
-
2014
- 2014-10-09 JP JP2015541641A patent/JP6518878B2/ja active Active
- 2014-10-09 EP EP14852053.9A patent/EP3056564B1/de active Active
- 2014-10-09 BR BR112016007833-0A patent/BR112016007833B1/pt active IP Right Grant
- 2014-10-09 AU AU2014332856A patent/AU2014332856B2/en active Active
- 2014-10-09 WO PCT/JP2014/077111 patent/WO2015053375A1/ja active Application Filing
- 2014-10-09 WO PCT/JP2014/077112 patent/WO2015053376A1/ja active Application Filing
- 2014-10-09 US US15/028,076 patent/US20160237403A1/en active Pending
- 2014-10-09 SG SG11201602796QA patent/SG11201602796QA/en unknown
- 2014-10-09 SG SG10201802877WA patent/SG10201802877WA/en unknown
- 2014-10-09 SG SG11201602734SA patent/SG11201602734SA/en unknown
- 2014-10-09 US US15/028,158 patent/US11492593B2/en active Active
- 2014-10-09 KR KR1020167012164A patent/KR102245015B1/ko active IP Right Grant
- 2014-10-09 AU AU2014332857A patent/AU2014332857B2/en active Active
- 2014-10-09 CA CA2926721A patent/CA2926721C/en active Active
- 2014-10-09 SG SG10201802879PA patent/SG10201802879PA/en unknown
- 2014-10-09 CA CA2926912A patent/CA2926912C/en active Active
- 2014-10-09 CN CN201480055588.9A patent/CN105849254A/zh active Pending
- 2014-10-09 KR KR1020167012163A patent/KR102253422B1/ko active IP Right Grant
- 2014-10-09 JP JP2015541642A patent/JP6518879B2/ja active Active
- 2014-10-09 EP EP14851809.5A patent/EP3056563B1/de active Active
- 2014-10-09 CN CN201480055673.5A patent/CN105829526A/zh active Pending
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2016
- 2016-05-06 ZA ZA201603054A patent/ZA201603054B/en unknown
- 2016-05-06 ZA ZA201603051A patent/ZA201603051B/en unknown
-
2019
- 2019-03-06 JP JP2019040104A patent/JP6850456B2/ja active Active
- 2019-03-06 JP JP2019040103A patent/JP6850455B2/ja active Active
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