SG10201802879PA - Method for purification of retinal pigment epithelial cells - Google Patents
Method for purification of retinal pigment epithelial cellsInfo
- Publication number
- SG10201802879PA SG10201802879PA SG10201802879PA SG10201802879PA SG10201802879PA SG 10201802879P A SG10201802879P A SG 10201802879PA SG 10201802879P A SG10201802879P A SG 10201802879PA SG 10201802879P A SG10201802879P A SG 10201802879PA SG 10201802879P A SG10201802879P A SG 10201802879PA
- Authority
- SG
- Singapore
- Prior art keywords
- purification
- epithelial cells
- retinal pigment
- pigment epithelial
- retinal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases (EC 2.)
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013212345 | 2013-10-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201802879PA true SG10201802879PA (en) | 2018-05-30 |
Family
ID=52813190
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201802879PA SG10201802879PA (en) | 2013-10-09 | 2014-10-09 | Method for purification of retinal pigment epithelial cells |
SG10201802877WA SG10201802877WA (en) | 2013-10-09 | 2014-10-09 | Method of producing retinal pigment epithelial cell |
SG11201602734SA SG11201602734SA (en) | 2013-10-09 | 2014-10-09 | Method of producing retinal pigment epithelial cell |
SG11201602796QA SG11201602796QA (en) | 2013-10-09 | 2014-10-09 | Method for purification of retinal pigment epithelial cells |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201802877WA SG10201802877WA (en) | 2013-10-09 | 2014-10-09 | Method of producing retinal pigment epithelial cell |
SG11201602734SA SG11201602734SA (en) | 2013-10-09 | 2014-10-09 | Method of producing retinal pigment epithelial cell |
SG11201602796QA SG11201602796QA (en) | 2013-10-09 | 2014-10-09 | Method for purification of retinal pigment epithelial cells |
Country Status (11)
Country | Link |
---|---|
US (2) | US20160237403A1 (en) |
EP (2) | EP3056563B1 (en) |
JP (4) | JP6518878B2 (en) |
KR (2) | KR102253422B1 (en) |
CN (2) | CN105829526A (en) |
AU (2) | AU2014332856B2 (en) |
BR (2) | BR112016007833B1 (en) |
CA (2) | CA2926721C (en) |
SG (4) | SG10201802879PA (en) |
WO (2) | WO2015053375A1 (en) |
ZA (2) | ZA201603054B (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011063005A2 (en) | 2009-11-17 | 2011-05-26 | Advanced Cell Technology, Inc. | Methods of producing human rpe cells and pharmaceutical preparations of human rpe cells |
BR112016007833B1 (en) | 2013-10-09 | 2023-03-28 | Healios K.K. | METHOD FOR PURIFICATION OF RETINAL PIGMENT EPITHELIAL CELLS AND METHOD FOR PRODUCTION OF RETINAL PIGMENT EPITHELIAL CELLS FROM A PLURIPOTENT STEM CELL |
CN105814195A (en) | 2013-11-27 | 2016-07-27 | 京都府公立大学法人 | Application of laminin to corneal endothelial cell culture |
MY183058A (en) | 2014-10-24 | 2021-02-09 | Riken | Production method for retinal tissue |
AU2015336453B2 (en) | 2014-10-24 | 2021-05-20 | Riken | Production method for nerve tissue |
EP3213761B1 (en) * | 2014-10-31 | 2021-05-19 | Kyoto Prefectural Public University Corporation | Novel treatment of retina using laminin |
CA2965770C (en) | 2014-10-31 | 2024-02-13 | Kyoto Prefectural Public University Corporation | Treatment of cornea using laminin |
CN105013010B (en) * | 2015-07-07 | 2018-01-12 | 中山大学中山眼科中心 | A kind of laminin film of auxiliary iPS RPE transplanting |
MY189778A (en) | 2015-09-08 | 2022-03-04 | Healios Kk | Method for producing retinal pigment epithelial cells |
JP6995314B2 (en) * | 2016-04-22 | 2022-02-21 | 大日本住友製薬株式会社 | Manufacturing method of retinal tissue |
CN110573610A (en) | 2017-03-08 | 2019-12-13 | 大日本住友制药株式会社 | Preparation method of retinal pigment epithelial cells |
CN110945119B (en) * | 2017-07-20 | 2024-04-05 | 国立研究开发法人理化学研究所 | Method for maturation of retinal tissue comprising continuous epithelium |
JP7162221B2 (en) | 2017-09-08 | 2022-10-28 | 国立研究開発法人理化学研究所 | Cell aggregate containing retinal tissue and method for producing the same |
CN108642014B (en) * | 2018-05-17 | 2019-10-08 | 山东兴瑞生物科技有限公司 | The method for preparing retinal pigment epithelium thin slice using autoimmune cell |
DK3810758T3 (en) * | 2018-06-20 | 2023-10-16 | Biolamina Ab | METHODS AND COMPOSITIONS FOR THE PRODUCTION OF RETINA PIGMENT EPITHELIAL CELLS |
EP3950953A4 (en) | 2019-03-29 | 2023-04-19 | Public University Corporation Yokohama City University | Screening method and toxicity evaluation method |
KR20220004097A (en) | 2019-04-26 | 2022-01-11 | 고쿠리쓰 겐큐 가이하쓰 호징 리가가쿠 겐큐소 | Complex comprising neural retina, retinal pigment epithelial cells, and hydrogel, and method for preparing the same |
JPWO2021241658A1 (en) | 2020-05-26 | 2021-12-02 | ||
CN116194079A (en) | 2020-09-11 | 2023-05-30 | 住友制药株式会社 | Medium for tissue for implantation |
TW202302839A (en) | 2021-03-09 | 2023-01-16 | 國立研究開發法人理化學研究所 | Method for producing hypoimmunogenic retinal pigment epithelial cells |
CN115261301A (en) * | 2021-04-30 | 2022-11-01 | 深圳华大生命科学研究院 | In-vitro induction and culture method of retinal pigment epithelial cells |
TW202305112A (en) | 2021-04-30 | 2023-02-01 | 國立研究開發法人理化學研究所 | Cord-like aggregates of retinal pigment epithelial cells, device and production method for producing same, and therapeutic agent comprising said cord-like aggregates |
CN115418343A (en) * | 2022-10-28 | 2022-12-02 | 深圳市俊元生物科技有限公司 | Method for extracting pluripotent stem cells from human retinal pigment epithelial cells |
CN116769713B (en) * | 2023-08-14 | 2023-10-27 | 四川大学华西医院 | Preparation method of retinal pigment epithelial cells |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8492147B2 (en) | 2004-06-18 | 2013-07-23 | Riken | Method of inducing the differentiation of embryonic stem cells into nerve by serum-free suspension culture |
EP1947170B1 (en) * | 2005-10-21 | 2018-08-08 | Kaneka Corporation | Stem cell separating material and method of separation |
US9133435B2 (en) * | 2007-01-18 | 2015-09-15 | Riken | Method for induction/differentiation into photoreceptor cell |
EP2147094B2 (en) | 2007-04-18 | 2018-02-21 | Hadasit Medical Research Services & Development Limited | Stem cell-derived retinal pigment epithelial cells |
JP5590646B2 (en) | 2009-10-08 | 2014-09-17 | 国立大学法人大阪大学 | Culture substrate for human pluripotent stem cells and use thereof |
JP2012080821A (en) | 2010-10-12 | 2012-04-26 | Univ Of Tsukuba | Method of concentrating nucleated cell component in blood |
MX348269B (en) * | 2011-02-25 | 2017-06-05 | Riken | Method of producing retinal pigment epithelial cell sheet. |
WO2013069503A1 (en) | 2011-11-09 | 2013-05-16 | 株式会社カネカ | Stem cell isolation method |
US9850463B2 (en) * | 2012-02-01 | 2017-12-26 | The Regents Of The University Of California | Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation |
US10519422B2 (en) | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
JP2013212345A (en) | 2012-04-03 | 2013-10-17 | Kurashiki Seni Kako Kk | Non-woven fabric for curtain and method of manufacturing the same |
BR112016007833B1 (en) | 2013-10-09 | 2023-03-28 | Healios K.K. | METHOD FOR PURIFICATION OF RETINAL PIGMENT EPITHELIAL CELLS AND METHOD FOR PRODUCTION OF RETINAL PIGMENT EPITHELIAL CELLS FROM A PLURIPOTENT STEM CELL |
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2014
- 2014-10-09 BR BR112016007833-0A patent/BR112016007833B1/en active IP Right Grant
- 2014-10-09 CA CA2926721A patent/CA2926721C/en active Active
- 2014-10-09 US US15/028,076 patent/US20160237403A1/en active Pending
- 2014-10-09 SG SG10201802879PA patent/SG10201802879PA/en unknown
- 2014-10-09 EP EP14851809.5A patent/EP3056563B1/en active Active
- 2014-10-09 US US15/028,158 patent/US11492593B2/en active Active
- 2014-10-09 WO PCT/JP2014/077111 patent/WO2015053375A1/en active Application Filing
- 2014-10-09 AU AU2014332856A patent/AU2014332856B2/en active Active
- 2014-10-09 CN CN201480055673.5A patent/CN105829526A/en active Pending
- 2014-10-09 WO PCT/JP2014/077112 patent/WO2015053376A1/en active Application Filing
- 2014-10-09 JP JP2015541641A patent/JP6518878B2/en active Active
- 2014-10-09 SG SG10201802877WA patent/SG10201802877WA/en unknown
- 2014-10-09 BR BR112016007853A patent/BR112016007853A2/en active Search and Examination
- 2014-10-09 SG SG11201602734SA patent/SG11201602734SA/en unknown
- 2014-10-09 KR KR1020167012163A patent/KR102253422B1/en active IP Right Grant
- 2014-10-09 SG SG11201602796QA patent/SG11201602796QA/en unknown
- 2014-10-09 KR KR1020167012164A patent/KR102245015B1/en active IP Right Grant
- 2014-10-09 JP JP2015541642A patent/JP6518879B2/en active Active
- 2014-10-09 CA CA2926912A patent/CA2926912C/en active Active
- 2014-10-09 AU AU2014332857A patent/AU2014332857B2/en active Active
- 2014-10-09 CN CN201480055588.9A patent/CN105849254A/en active Pending
- 2014-10-09 EP EP14852053.9A patent/EP3056564B1/en active Active
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2016
- 2016-05-06 ZA ZA201603054A patent/ZA201603054B/en unknown
- 2016-05-06 ZA ZA201603051A patent/ZA201603051B/en unknown
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2019
- 2019-03-06 JP JP2019040104A patent/JP6850456B2/en active Active
- 2019-03-06 JP JP2019040103A patent/JP6850455B2/en active Active
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