SG11201602452SA - Composition for preventing or treating amyotrophic lateral sclerosis using two or more isoforms of hepatocyte growth factor - Google Patents
Composition for preventing or treating amyotrophic lateral sclerosis using two or more isoforms of hepatocyte growth factorInfo
- Publication number
- SG11201602452SA SG11201602452SA SG11201602452SA SG11201602452SA SG11201602452SA SG 11201602452S A SG11201602452S A SG 11201602452SA SG 11201602452S A SG11201602452S A SG 11201602452SA SG 11201602452S A SG11201602452S A SG 11201602452SA SG 11201602452S A SG11201602452S A SG 11201602452SA
- Authority
- SG
- Singapore
- Prior art keywords
- isoforms
- preventing
- composition
- growth factor
- lateral sclerosis
- Prior art date
Links
- 102000003745 Hepatocyte Growth Factor Human genes 0.000 title 1
- 108090000100 Hepatocyte Growth Factor Proteins 0.000 title 1
- 102000001708 Protein Isoforms Human genes 0.000 title 1
- 108010029485 Protein Isoforms Proteins 0.000 title 1
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Psychiatry (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20130126216 | 2013-10-22 | ||
| KR1020140143377A KR101779775B1 (ko) | 2013-10-22 | 2014-10-22 | 간세포 성장인자의 둘 이상의 이형체를 이용한 근위축성 측삭 경화증 예방 또는 치료용 조성물 |
| PCT/KR2014/009971 WO2015060650A2 (ko) | 2013-10-22 | 2014-10-22 | 간세포 성장인자의 둘 이상의 이형체를 이용한 근위축성 측삭 경화증 예방 또는 치료용 조성물 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201602452SA true SG11201602452SA (en) | 2016-05-30 |
Family
ID=53386224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201602452SA SG11201602452SA (en) | 2013-10-22 | 2014-10-22 | Composition for preventing or treating amyotrophic lateral sclerosis using two or more isoforms of hepatocyte growth factor |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10639351B2 (zh) |
| EP (1) | EP3061457B1 (zh) |
| JP (1) | JP6240337B2 (zh) |
| KR (2) | KR101779775B1 (zh) |
| CN (1) | CN105682676B (zh) |
| AU (1) | AU2014337870B2 (zh) |
| BR (1) | BR112016008267A2 (zh) |
| CA (1) | CA2926607C (zh) |
| ES (1) | ES2773305T3 (zh) |
| HK (1) | HK1219873A1 (zh) |
| MX (1) | MX2016005006A (zh) |
| RU (1) | RU2639582C2 (zh) |
| SG (1) | SG11201602452SA (zh) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3046202B1 (fr) * | 2015-12-24 | 2017-12-29 | Snecma | Turboreacteur avec un moyen de reprise de poussee sur le carter inter-compresseurs |
| WO2019132624A1 (ko) | 2017-12-29 | 2019-07-04 | 주식회사 헬릭스미스 | 하이브리드 hgf 유전자가 도입된 aav(아데노-연관 바이러스) 벡터 |
| WO2020079489A2 (en) * | 2018-07-17 | 2020-04-23 | Helixmith Co., Ltd. | Treatment of neuropathy with igf-1-encoding dna constructs and hgf-encoding dna constructs |
| CN110577954A (zh) * | 2019-10-12 | 2019-12-17 | 北京万福来生物技术有限责任公司 | 突变的肝细胞生长因子基因及其应用 |
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| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| NZ232813A (en) | 1989-03-10 | 1992-08-26 | Snow Brand Milk Products Co Ltd | Human fibroblast glycoprotein, cell differentiation, blood vessel endothelial cell growth factor, cellular immunology inforcing factor of 78 or 74 thousand daltons plus or minus two thousand daltons |
| US5693622A (en) | 1989-03-21 | 1997-12-02 | Vical Incorporated | Expression of exogenous polynucleotide sequences cardiac muscle of a mammal |
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| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| CA2022752C (en) | 1989-08-11 | 1998-07-07 | Naomi Kitamura | Hepatic parenchymal cell growth factor, gene encoding the same, process for producing the factor, and transformants producing the factor |
| US6706694B1 (en) | 1990-03-21 | 2004-03-16 | Vical Incorporated | Expression of exogenous polynucleotide sequences in a vertebrate |
| EP0539590B1 (en) | 1990-07-13 | 1999-03-31 | Snow Brand Milk Products Co., Ltd. | Plasmid containing dna which codes for the amino acid sequence of tcf-ii, transformed cell, and production of physiologically active substance by using the same |
| US5661133B1 (en) | 1991-11-12 | 1999-06-01 | Univ Michigan | Collateral blood vessel formation in cardiac muscle by injecting a dna sequence encoding an angiogenic protein |
| US7323297B1 (en) | 1992-04-03 | 2008-01-29 | The Regents Of The University Of California | Stabilized polynucleotide complexes and methods |
| JP3680114B2 (ja) | 1993-09-17 | 2005-08-10 | 敏一 中村 | 脳神経障害治療剤 |
| US6498144B1 (en) | 1993-10-18 | 2002-12-24 | North Shore - Long Island Jewish Research Institute | Use of scatter factor to enhance angiogenesis |
| US5837676A (en) | 1993-10-18 | 1998-11-17 | Long Island Jewish Medical Center | Use of scatter factor to enhance angiogenesis |
| US5652225A (en) | 1994-10-04 | 1997-07-29 | St. Elizabeth's Medical Center Of Boston, Inc. | Methods and products for nucleic acid delivery |
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| US20030148968A1 (en) | 1995-02-28 | 2003-08-07 | Hammond H. Kirk | Techniques and compositions for treating cardiovascular disease by in vivo gene delivery |
| JP3927248B2 (ja) | 1995-07-11 | 2007-06-06 | 第一製薬株式会社 | Ｈｇｆ凍結乾燥製剤 |
| ES2240999T3 (es) | 1995-08-29 | 2005-10-16 | Anges Mg, Inc. | Medicamento que contiene un gen del hgf. |
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| US6121246A (en) | 1995-10-20 | 2000-09-19 | St. Elizabeth's Medical Center Of Boston, Inc. | Method for treating ischemic tissue |
| WO1998050079A2 (en) | 1997-05-06 | 1998-11-12 | The Regents Of The University Of California | Techniques and compositions for treating heart failure and ventricular remodeling by in vivo delivery of angiogenic transgenes |
| WO1999036103A1 (en) | 1998-01-16 | 1999-07-22 | Mcgill University | Prevention and treatment of neuropathy by hepatocyte growth factor |
| JPH11246433A (ja) | 1998-03-03 | 1999-09-14 | Sumitomo Pharmaceut Co Ltd | 心筋梗塞治療剤 |
| US20040228834A1 (en) | 1998-03-09 | 2004-11-18 | Jeffrey Isner | Compositions and methods for modulating vascularization |
| EP1061800A4 (en) | 1998-03-09 | 2004-10-06 | Caritas St Elizabeths Boston | COMPOSITIONS AND METHODS FOR MODULATING THE VASCULARIZATION |
| WO1999045966A1 (en) | 1998-03-13 | 1999-09-16 | American Home Products Corporation | Polynucleotide composition, method of preparation, and use thereof |
| US7276359B1 (en) | 1998-03-13 | 2007-10-02 | Wyeth | Polynucleotide composition, method of preparation, and use thereof |
| DK1061955T3 (da) | 1998-03-13 | 2005-07-04 | Wyeth Corp | Polynukleotidsammensætning, fremstillingsmetode og anvendelse deraf |
| US6887477B1 (en) | 1998-08-05 | 2005-05-03 | Tomokazu Nagano | Method of treating ischemic disease by intramuscular administration of Hepatocyte growth factor |
| KR20000046969A (ko) | 1998-12-31 | 2000-07-25 | 이선경 | 이종 유전자 유래의 유전자 발현 조절요소를 포함하는 강력한전사 활성을 가진 진핵세포 발현벡더 |
| CN1182874C (zh) | 1999-10-29 | 2005-01-05 | 安增子摩祺株式会社 | 糖尿病性局部缺血疾病的基因治疗制剂 |
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| EP1578193A4 (en) | 2002-12-23 | 2011-06-15 | Vical Inc | FREEZING PROCESS FOR NUCLEIC ACID / BLOCK COPOLYMER / CATION SIDE COMPLEXES |
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| US20070212390A1 (en) | 2005-09-22 | 2007-09-13 | Ludwig Institute For Cancer Research | Protease-resistant forms of VEGF-D, method of making and method of use |
| BRPI0618488A2 (pt) | 2005-11-10 | 2011-08-30 | Receptor Biologix Inc | proteìnas de fusão de ìntron de fator de crescimento de hepatócito |
| EP2022853A4 (en) | 2006-05-17 | 2010-03-10 | Yoshiyuki Koyama | FREEZERED PRODUCT FOR THE TRANSFER OF NUCLEIC ACID, OLIGONUCLEIC ACID OR DERIVATIVES THEREOF |
| WO2007142651A1 (en) | 2006-06-09 | 2007-12-13 | Caritas St. Elizabeth Medical Center Of Boston, Inc. | Methods and compositions for the treatment of neuropathy |
| CA2682469A1 (en) | 2007-03-30 | 2008-10-09 | The Cleveland Clinic Foundation | Method of treating ischemic disorders |
| US8435953B2 (en) | 2007-11-07 | 2013-05-07 | Yasuhiko Tabata | Sustained release composition containing SDF-1 |
| US20090202606A1 (en) | 2008-01-25 | 2009-08-13 | Viromed Co., Ltd. | Treatment and Prevention of Cardiac Conditions Using Two or More Isoforms of Hepatocyte Growth Factor |
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| RU2413524C1 (ru) * | 2009-07-31 | 2011-03-10 | Общество с ограниченной ответственностью "КриоЦентр" | Способ лечения психических и неврологических расстройств |
| KR101891352B1 (ko) | 2009-12-23 | 2018-08-24 | 큐알엔에이, 인크. | 간세포 성장 인자(ｈｇｆ)에 대한 천연 안티센스 전사체의 억제에 의한 ｈｇｆ 관련 질환의 치료 |
| WO2012025925A1 (en) | 2010-08-24 | 2012-03-01 | Rappaport Family Institute For Research In The Medical Sciences | Methods of improving transplantation using sdf-1alpha |
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| WO2013037521A1 (en) * | 2011-09-16 | 2013-03-21 | Medical Research Council | Modified hgf-1k1 polypeptide |
| JP2013129661A (ja) * | 2013-02-20 | 2013-07-04 | Toshiichi Nakamura | 筋萎縮性側索硬化症治療剤 |
-
2014
- 2014-10-22 US US15/030,999 patent/US10639351B2/en active Active
- 2014-10-22 AU AU2014337870A patent/AU2014337870B2/en active Active
- 2014-10-22 RU RU2016119116A patent/RU2639582C2/ru active
- 2014-10-22 ES ES14856385T patent/ES2773305T3/es active Active
- 2014-10-22 CN CN201480058075.3A patent/CN105682676B/zh active Active
- 2014-10-22 CA CA2926607A patent/CA2926607C/en active Active
- 2014-10-22 MX MX2016005006A patent/MX2016005006A/es active IP Right Grant
- 2014-10-22 SG SG11201602452SA patent/SG11201602452SA/en unknown
- 2014-10-22 JP JP2016546724A patent/JP6240337B2/ja active Active
- 2014-10-22 BR BR112016008267A patent/BR112016008267A2/pt not_active Application Discontinuation
- 2014-10-22 KR KR1020140143377A patent/KR101779775B1/ko active IP Right Grant
- 2014-10-22 EP EP14856385.1A patent/EP3061457B1/en active Active
-
2016
- 2016-07-06 HK HK16107864.0A patent/HK1219873A1/zh unknown
-
2017
- 2017-08-31 KR KR1020170110892A patent/KR101860452B1/ko active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2926607C (en) | 2018-10-23 |
| CN105682676B (zh) | 2020-10-23 |
| KR20150047108A (ko) | 2015-05-04 |
| JP2016534149A (ja) | 2016-11-04 |
| BR112016008267A2 (pt) | 2017-10-03 |
| KR101779775B1 (ko) | 2017-09-21 |
| EP3061457B1 (en) | 2020-01-22 |
| CN105682676A (zh) | 2016-06-15 |
| KR101860452B1 (ko) | 2018-05-24 |
| CA2926607A1 (en) | 2015-04-30 |
| US10639351B2 (en) | 2020-05-05 |
| US20160250291A1 (en) | 2016-09-01 |
| EP3061457A4 (en) | 2017-06-07 |
| KR20170104129A (ko) | 2017-09-14 |
| JP6240337B2 (ja) | 2017-11-29 |
| RU2639582C2 (ru) | 2017-12-21 |
| HK1219873A1 (zh) | 2017-04-21 |
| RU2016119116A (ru) | 2017-11-28 |
| MX2016005006A (es) | 2016-07-14 |
| EP3061457A2 (en) | 2016-08-31 |
| AU2014337870B2 (en) | 2019-11-28 |
| ES2773305T3 (es) | 2020-07-10 |
| AU2014337870A1 (en) | 2016-05-05 |
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