SG11201601036UA - Cortistatin analogues for the treatment of inflammatory and/or immune diseases - Google Patents

Cortistatin analogues for the treatment of inflammatory and/or immune diseases

Info

Publication number
SG11201601036UA
SG11201601036UA SG11201601036UA SG11201601036UA SG11201601036UA SG 11201601036U A SG11201601036U A SG 11201601036UA SG 11201601036U A SG11201601036U A SG 11201601036UA SG 11201601036U A SG11201601036U A SG 11201601036UA SG 11201601036U A SG11201601036U A SG 11201601036UA
Authority
SG
Singapore
Prior art keywords
inflammatory
treatment
immune diseases
cortistatin analogues
cortistatin
Prior art date
Application number
SG11201601036UA
Other languages
English (en)
Inventor
Obiols Berta Ponsati
Carneado Jimena Fernández
Josep Farrera-Sinfreu
Dueña Antonio Parente
Original Assignee
Bcn Peptides Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bcn Peptides Sa filed Critical Bcn Peptides Sa
Publication of SG11201601036UA publication Critical patent/SG11201601036UA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • C07K14/6555Somatostatins at least 1 amino acid in D-form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Birds (AREA)
SG11201601036UA 2013-09-18 2014-09-17 Cortistatin analogues for the treatment of inflammatory and/or immune diseases SG11201601036UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13382361 2013-09-18
PCT/EP2014/069842 WO2015040089A1 (en) 2013-09-18 2014-09-17 Co rti statin analogues for the treatment of inflammatory and/or immune diseases

Publications (1)

Publication Number Publication Date
SG11201601036UA true SG11201601036UA (en) 2016-04-28

Family

ID=49880656

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201601036UA SG11201601036UA (en) 2013-09-18 2014-09-17 Cortistatin analogues for the treatment of inflammatory and/or immune diseases

Country Status (24)

Country Link
US (1) US20160185822A1 (lt)
EP (1) EP3046933B1 (lt)
JP (1) JP6989260B2 (lt)
KR (1) KR102285939B1 (lt)
CN (1) CN105579467B (lt)
AU (1) AU2014323131B2 (lt)
BR (1) BR112016005731B1 (lt)
CA (1) CA2921324C (lt)
CL (1) CL2016000392A1 (lt)
DK (1) DK3046933T3 (lt)
ES (1) ES2728319T3 (lt)
HK (1) HK1218122A1 (lt)
HU (1) HUE043206T2 (lt)
IL (1) IL244317B (lt)
LT (1) LT3046933T (lt)
MX (1) MX368373B (lt)
MY (1) MY185593A (lt)
NZ (1) NZ717035A (lt)
PL (1) PL3046933T3 (lt)
PT (1) PT3046933T (lt)
RU (1) RU2678315C2 (lt)
SG (1) SG11201601036UA (lt)
UA (1) UA119148C2 (lt)
WO (1) WO2015040089A1 (lt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016014760A2 (pt) 2013-12-24 2017-12-12 Harvard College composto, composição farmacêutica, métodos para tratamento de uma condição, para inibir e validar atividade de cinase, para modular o trajeto de b-catenina e o trajeto de tgfb/bmp em uma célula, para modular a atividade de stat1 e de hif-1-alfa em uma célula, para aumentar a expressão de bim e para preparar um composto, mutante, e, proteína
WO2016182932A1 (en) 2015-05-08 2016-11-17 President And Fellows Of Harvard College Cortistatin analogues, syntheses, and uses thereof
EP3316889A4 (en) 2015-07-01 2018-11-14 President and Fellows of Harvard College Cortistatin analogues and syntheses and uses thereof
JP2020526515A (ja) * 2017-07-05 2020-08-31 ウィスコンシン・アルムナイ・リサーチ・ファウンデーションWisconsin Alumni Research Foundation 遺伝子送達成果を改善する核酸と抗炎症性分子の共送達のためのミネラルコーティングされたマイクロ粒子
CA3089108A1 (en) * 2018-01-31 2019-08-08 Twi Pharmaceuticals, Inc. Topical formulations comprising tofacitinib
WO2019183686A1 (en) 2018-03-29 2019-10-03 Lateral IP Pty Ltd Cyclic peptides and uses thereof
RU2698451C1 (ru) * 2018-07-02 2019-08-27 Павел Александрович Храмов Средство и способ для лечения нейросенсорной тугоухости
ES2780274A1 (es) * 2019-02-15 2020-08-24 Consejo Superior De Investig Científicas (Csic) Cortistatina o un análogo de la misma como agente farmacéuticamente activo en forma latente
JP2023504533A (ja) * 2019-12-05 2023-02-03 ベセエネ ペプチドス エセ.ア. 癌および/または転移の治療のためのペプチド
CN111297876B (zh) * 2020-01-16 2021-04-27 武汉理工大学 一种塞来昔布胶束和和厚朴酚胶束药物联用控释系统及其制备方法
CN113797314B (zh) * 2021-09-29 2023-08-22 山东大学齐鲁医院 Cst多肽在制备股骨头坏死治疗药物中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6660843B1 (en) * 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
EP1040837A3 (en) 1999-02-26 2002-01-02 Erasmus Universiteit Rotterdam Medicaments for the treatment of a choroidal neovascularization (CNV) related disorder
RU2008132149A (ru) 2006-01-05 2010-02-10 Юниверсити Оф Юта Рисерч Фаундейшн (Us) Способы и композиции, имеющие отношение к улучшенным свойствам фармакологических средств, целенаправленно действующих на нервную систему
WO2007082980A1 (es) 2006-01-23 2007-07-26 Consejo Superior De Investigaciones Científicas Composiciones y procedimientos para tratar trastornos inflamatorios e inmunitarios con cortistatina
WO2009043523A2 (en) 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Cortistatin 17 and neuropeptide 1 for use as therapeutic agent
EP2168983A1 (fr) * 2008-09-30 2010-03-31 Ipsen Pharma Nouveaux composés octapeptidiques et leur utilisation thérapeutique
ES2351569B8 (es) * 2009-05-07 2012-06-20 Bcn Peptides S.A. Ligandos peptídicos de receptores de somatostatina.

Also Published As

Publication number Publication date
US20160185822A1 (en) 2016-06-30
MX2016003490A (es) 2016-07-06
IL244317B (en) 2020-06-30
PT3046933T (pt) 2019-05-31
MX368373B (es) 2019-09-27
MY185593A (en) 2021-05-24
ES2728319T3 (es) 2019-10-23
DK3046933T3 (da) 2019-05-13
NZ717035A (en) 2019-11-29
CN105579467A (zh) 2016-05-11
RU2678315C2 (ru) 2019-01-28
HUE043206T2 (hu) 2019-08-28
CL2016000392A1 (es) 2016-11-11
WO2015040089A1 (en) 2015-03-26
IL244317A0 (en) 2016-04-21
AU2014323131A1 (en) 2016-03-10
CA2921324A1 (en) 2015-03-26
JP2016535760A (ja) 2016-11-17
CN105579467B (zh) 2021-03-09
AU2014323131B2 (en) 2018-08-09
HK1218122A1 (zh) 2017-02-03
EP3046933B1 (en) 2019-02-27
UA119148C2 (uk) 2019-05-10
CA2921324C (en) 2022-11-22
RU2016109410A3 (lt) 2018-05-24
KR20160054512A (ko) 2016-05-16
RU2016109410A (ru) 2017-10-18
KR102285939B1 (ko) 2021-08-05
PL3046933T3 (pl) 2019-08-30
LT3046933T (lt) 2019-05-27
BR112016005731B1 (pt) 2023-01-17
BR112016005731A2 (lt) 2017-08-01
EP3046933A1 (en) 2016-07-27
JP6989260B2 (ja) 2022-01-05

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