DK3046933T3 - Cortistatin-analoger til behandling af inflammations- og/eller immunsygdomme - Google Patents

Cortistatin-analoger til behandling af inflammations- og/eller immunsygdomme Download PDF

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Publication number
DK3046933T3
DK3046933T3 DK14766508.7T DK14766508T DK3046933T3 DK 3046933 T3 DK3046933 T3 DK 3046933T3 DK 14766508 T DK14766508 T DK 14766508T DK 3046933 T3 DK3046933 T3 DK 3046933T3
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Denmark
Prior art keywords
immunal
inflammation
diseases
treatment
cortistatin analogs
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Application number
DK14766508.7T
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English (en)
Inventor
Obiols Berta Ponsati
Carneado Jimena FernãNdez
Josep Farrera-Sinfreu
Duena Antonio Parente
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Bcn Peptides Sa
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Publication of DK3046933T3 publication Critical patent/DK3046933T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • C07K14/6555Somatostatins at least 1 amino acid in D-form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Birds (AREA)
DK14766508.7T 2013-09-18 2014-09-17 Cortistatin-analoger til behandling af inflammations- og/eller immunsygdomme DK3046933T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13382361 2013-09-18
PCT/EP2014/069842 WO2015040089A1 (en) 2013-09-18 2014-09-17 Co rti statin analogues for the treatment of inflammatory and/or immune diseases

Publications (1)

Publication Number Publication Date
DK3046933T3 true DK3046933T3 (da) 2019-05-13

Family

ID=49880656

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14766508.7T DK3046933T3 (da) 2013-09-18 2014-09-17 Cortistatin-analoger til behandling af inflammations- og/eller immunsygdomme

Country Status (24)

Country Link
US (1) US20160185822A1 (da)
EP (1) EP3046933B1 (da)
JP (1) JP6989260B2 (da)
KR (1) KR102285939B1 (da)
CN (1) CN105579467B (da)
AU (1) AU2014323131B2 (da)
BR (1) BR112016005731B1 (da)
CA (1) CA2921324C (da)
CL (1) CL2016000392A1 (da)
DK (1) DK3046933T3 (da)
ES (1) ES2728319T3 (da)
HK (1) HK1218122A1 (da)
HU (1) HUE043206T2 (da)
IL (1) IL244317B (da)
LT (1) LT3046933T (da)
MX (1) MX368373B (da)
MY (1) MY185593A (da)
NZ (1) NZ717035A (da)
PL (1) PL3046933T3 (da)
PT (1) PT3046933T (da)
RU (1) RU2678315C2 (da)
SG (1) SG11201601036UA (da)
UA (1) UA119148C2 (da)
WO (1) WO2015040089A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY180383A (en) 2013-12-24 2020-11-28 Harvard College Cortistatin analogues and syntheses and uses thereof
EP3294298A4 (en) 2015-05-08 2018-10-17 President and Fellows of Harvard College Cortistatin analogues, syntheses, and uses thereof
EP3316889A4 (en) 2015-07-01 2018-11-14 President and Fellows of Harvard College Cortistatin analogues and syntheses and uses thereof
CA3068917A1 (en) 2017-07-05 2019-01-10 Wisconsin Alumni Research Foundation Mineral coated microparticles for co-delivery of anti-inflammatory molecules with nucleic acids to improve gene delivery outcomes
WO2019152232A1 (en) * 2018-01-31 2019-08-08 Twi Pharmaceuticals, Inc. Topical formulations comprising tofacitinib
AU2019240773B2 (en) 2018-03-29 2024-05-16 Lateral IP Pty Ltd Cyclic peptides and uses thereof
RU2698451C1 (ru) * 2018-07-02 2019-08-27 Павел Александрович Храмов Средство и способ для лечения нейросенсорной тугоухости
ES2780274A1 (es) * 2019-02-15 2020-08-24 Consejo Superior De Investig Científicas (Csic) Cortistatina o un análogo de la misma como agente farmacéuticamente activo en forma latente
CA3163483A1 (en) * 2019-12-05 2021-06-10 Bcn Peptides, S.A. Peptides for the treatment of cancer and/or metastasis
CN111297876B (zh) * 2020-01-16 2021-04-27 武汉理工大学 一种塞来昔布胶束和和厚朴酚胶束药物联用控释系统及其制备方法
CN113797314B (zh) * 2021-09-29 2023-08-22 山东大学齐鲁医院 Cst多肽在制备股骨头坏死治疗药物中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6660843B1 (en) * 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
EP1040837A3 (en) 1999-02-26 2002-01-02 Erasmus Universiteit Rotterdam Medicaments for the treatment of a choroidal neovascularization (CNV) related disorder
JP2009523129A (ja) 2006-01-05 2009-06-18 ユニバーシティ オブ ユタ リサーチ ファウンデーション 神経系を標的する薬理学的物質の性質を改善することに関連する方法および組成物
WO2007082980A1 (es) * 2006-01-23 2007-07-26 Consejo Superior De Investigaciones Científicas Composiciones y procedimientos para tratar trastornos inflamatorios e inmunitarios con cortistatina
WO2009043523A2 (en) 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Cortistatin 17 and neuropeptide 1 for use as therapeutic agent
EP2168983A1 (fr) * 2008-09-30 2010-03-31 Ipsen Pharma Nouveaux composés octapeptidiques et leur utilisation thérapeutique
ES2351569B8 (es) * 2009-05-07 2012-06-20 Bcn Peptides S.A. Ligandos peptídicos de receptores de somatostatina.

Also Published As

Publication number Publication date
KR102285939B1 (ko) 2021-08-05
CN105579467A (zh) 2016-05-11
MX368373B (es) 2019-09-27
US20160185822A1 (en) 2016-06-30
AU2014323131B2 (en) 2018-08-09
NZ717035A (en) 2019-11-29
RU2016109410A3 (da) 2018-05-24
WO2015040089A1 (en) 2015-03-26
AU2014323131A1 (en) 2016-03-10
RU2678315C2 (ru) 2019-01-28
BR112016005731B1 (pt) 2023-01-17
CA2921324A1 (en) 2015-03-26
EP3046933B1 (en) 2019-02-27
IL244317A0 (en) 2016-04-21
ES2728319T3 (es) 2019-10-23
UA119148C2 (uk) 2019-05-10
CA2921324C (en) 2022-11-22
CN105579467B (zh) 2021-03-09
HUE043206T2 (hu) 2019-08-28
CL2016000392A1 (es) 2016-11-11
MY185593A (en) 2021-05-24
PT3046933T (pt) 2019-05-31
EP3046933A1 (en) 2016-07-27
KR20160054512A (ko) 2016-05-16
SG11201601036UA (en) 2016-04-28
JP2016535760A (ja) 2016-11-17
MX2016003490A (es) 2016-07-06
IL244317B (en) 2020-06-30
HK1218122A1 (zh) 2017-02-03
LT3046933T (lt) 2019-05-27
RU2016109410A (ru) 2017-10-18
BR112016005731A2 (da) 2017-08-01
PL3046933T3 (pl) 2019-08-30
JP6989260B2 (ja) 2022-01-05

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