SG11201507467VA - Sovaprevir polymorphs and methods of manufacture thereof - Google Patents
Sovaprevir polymorphs and methods of manufacture thereofInfo
- Publication number
- SG11201507467VA SG11201507467VA SG11201507467VA SG11201507467VA SG11201507467VA SG 11201507467V A SG11201507467V A SG 11201507467VA SG 11201507467V A SG11201507467V A SG 11201507467VA SG 11201507467V A SG11201507467V A SG 11201507467VA SG 11201507467V A SG11201507467V A SG 11201507467VA
- Authority
- SG
- Singapore
- Prior art keywords
- sovaprevir
- polymorphs
- manufacture
- methods
- sovaprevir polymorphs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361786927P | 2013-03-15 | 2013-03-15 | |
PCT/US2014/028348 WO2014144087A1 (en) | 2013-03-15 | 2014-03-14 | Sovaprevir polymorphs and methods of manufacture thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201507467VA true SG11201507467VA (en) | 2015-10-29 |
Family
ID=50483591
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201507467VA SG11201507467VA (en) | 2013-03-15 | 2014-03-14 | Sovaprevir polymorphs and methods of manufacture thereof |
Country Status (11)
Country | Link |
---|---|
US (2) | US9227952B2 (ko) |
EP (1) | EP2970192A1 (ko) |
JP (1) | JP2016513732A (ko) |
KR (1) | KR20160005686A (ko) |
AU (1) | AU2014227849A1 (ko) |
BR (1) | BR112015023351A2 (ko) |
IL (1) | IL241290A0 (ko) |
MX (1) | MX2015013020A (ko) |
PH (1) | PH12015502122A1 (ko) |
SG (1) | SG11201507467VA (ko) |
WO (1) | WO2014144087A1 (ko) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA017448B1 (ru) | 2006-07-13 | 2012-12-28 | Ачиллион Фармасьютикалз, Инк. | 4-амино-4-оксобутаноиловые пептиды как ингибиторы вирусной репликации |
GB201112231D0 (en) | 2011-07-15 | 2011-08-31 | Verdant Bioproducts Ltd | Micro-organism |
EP3454856A4 (en) | 2016-05-10 | 2019-12-25 | C4 Therapeutics, Inc. | HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
EP3455218A4 (en) | 2016-05-10 | 2019-12-18 | C4 Therapeutics, Inc. | C3 CARBON-BASED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
WO2017197036A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Spirocyclic degronimers for target protein degradation |
Family Cites Families (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69002950T2 (de) | 1989-07-19 | 1994-01-20 | Upjohn Co | Peptide mit diaminoglycolen als übergangszustandmimik. |
CA2137832C (en) | 1992-06-12 | 2000-09-26 | Dennis J. Hoover | Inhibitors of angiotensin i chymase(s) including human heart chymase |
US6608027B1 (en) | 1999-04-06 | 2003-08-19 | Boehringer Ingelheim (Canada) Ltd | Macrocyclic peptides active against the hepatitis C virus |
DE60119968T2 (de) | 2000-11-20 | 2007-01-18 | Bristol-Myers Squibb Co. | Hepatitis c tripeptid inhibitoren |
US6867185B2 (en) | 2001-12-20 | 2005-03-15 | Bristol-Myers Squibb Company | Inhibitors of hepatitis C virus |
US7119072B2 (en) | 2002-01-30 | 2006-10-10 | Boehringer Ingelheim (Canada) Ltd. | Macrocyclic peptides active against the hepatitis C virus |
AU2003248535A1 (en) | 2002-05-20 | 2003-12-12 | Bristol-Myers Squibb Company | Heterocyclicsulfonamide hepatitis c virus inhibitors |
AU2003299519A1 (en) | 2002-05-20 | 2004-05-04 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
US20060199773A1 (en) | 2002-05-20 | 2006-09-07 | Sausker Justin B | Crystalline forms of (1R,2S)-N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(6-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-cyclopropanecarboxamide, monopotassium salt |
US6878722B2 (en) | 2002-05-20 | 2005-04-12 | Bristol-Myers Squibb Company | Substituted cycloalkyl P1′ hepatitis C virus inhibitors |
MY140680A (en) | 2002-05-20 | 2010-01-15 | Bristol Myers Squibb Co | Hepatitis c virus inhibitors |
KR100840715B1 (ko) | 2002-05-28 | 2008-06-23 | 삼성전자주식회사 | 백 라이트 어셈블리 및 이를 갖는 액정 표시 장치 |
EP1408031A1 (en) | 2002-10-09 | 2004-04-14 | 3 D Gene Pharma | Pyrolidine derivatives useful in treatment of hepatitis C virus infection |
US7601709B2 (en) | 2003-02-07 | 2009-10-13 | Enanta Pharmaceuticals, Inc. | Macrocyclic hepatitis C serine protease inhibitors |
JP2007524576A (ja) | 2003-02-07 | 2007-08-30 | エナンタ ファーマシューティカルズ インコーポレイテッド | 大環状のc型肝炎セリンプロテアーゼ阻害剤 |
CA2516018C (en) | 2003-03-05 | 2011-08-23 | Boehringer Ingelheim International Gmbh | Hepatitis c inhibitor peptide analogs |
ES2386161T3 (es) | 2003-04-16 | 2012-08-10 | Bristol-Myers Squibb Company | Proceso para separar una mezcla de enantiómeros de éster alquílico usando una enzima |
US7176208B2 (en) | 2003-04-18 | 2007-02-13 | Enanta Pharmaceuticals, Inc. | Quinoxalinyl macrocyclic hepatitis C serine protease inhibitors |
BRPI0410456B8 (pt) | 2003-05-21 | 2021-05-25 | Boehringer Ingelheim Int | compostos inibidores de hepatite c, composição farmacêutica, uso dos mesmos, bem como artigo de fabricação |
WO2004113365A2 (en) | 2003-06-05 | 2004-12-29 | Enanta Pharmaceuticals, Inc. | Hepatitis c serine protease tri-peptide inhibitors |
EP2368900A3 (en) | 2003-07-18 | 2012-07-04 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases, particularly hcv ns3-ns4a protease |
AU2004274051A1 (en) | 2003-09-22 | 2005-03-31 | Boehringer Ingelheim International Gmbh | Macrocyclic peptides active against the hepatitis C virus |
US7491794B2 (en) | 2003-10-14 | 2009-02-17 | Intermune, Inc. | Macrocyclic compounds as inhibitors of viral replication |
CN102020697B (zh) | 2003-10-14 | 2014-10-29 | F·霍夫曼-罗须公司 | 作为hcv复制抑制剂的巨环羧酸和酰基磺酰胺 |
US7132504B2 (en) | 2003-11-12 | 2006-11-07 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US7135462B2 (en) | 2003-11-20 | 2006-11-14 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US7309708B2 (en) | 2003-11-20 | 2007-12-18 | Birstol-Myers Squibb Company | Hepatitis C virus inhibitors |
CA2549851C (en) | 2004-01-21 | 2012-09-11 | Boehringer Ingelheim International Gmbh | Macrocyclic peptides active against the hepatitis c virus |
DK1713823T3 (da) | 2004-01-30 | 2010-03-08 | Medivir Ab | HCV NS-3 serinproteaseinhibitorer |
ATE459638T1 (de) | 2004-03-15 | 2010-03-15 | Boehringer Ingelheim Int | Verfahren zur herstellung makrocyclischer dipeptide, die sich für die behandlung von hepatitis-c-virusinfektionen eignen |
WO2005095403A2 (en) | 2004-03-30 | 2005-10-13 | Intermune, Inc. | Macrocyclic compounds as inhibitors of viral replication |
JP5676839B2 (ja) | 2004-07-16 | 2015-02-25 | ギリアード サイエンシーズ, インコーポレイテッド | 抗ウイルス化合物 |
UY29016A1 (es) | 2004-07-20 | 2006-02-24 | Boehringer Ingelheim Int | Analogos de dipeptidos inhibidores de la hepatitis c |
CA2573346C (en) | 2004-07-20 | 2011-09-20 | Boehringer Ingelheim International Gmbh | Hepatitis c inhibitor peptide analogs |
US7153848B2 (en) | 2004-08-09 | 2006-12-26 | Bristol-Myers Squibb Company | Inhibitors of HCV replication |
WO2006033878A1 (en) | 2004-09-17 | 2006-03-30 | Boehringer Ingelheim International, Gmbh | Process for preparing macrocyclic hcv protease inhibitors |
US7659263B2 (en) | 2004-11-12 | 2010-02-09 | Japan Tobacco Inc. | Thienopyrrole compound and use thereof as HCV polymerase inhibitor |
US7323447B2 (en) | 2005-02-08 | 2008-01-29 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
WO2006096652A2 (en) | 2005-03-08 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Process for preparing macrocyclic compounds |
US7592336B2 (en) | 2005-05-10 | 2009-09-22 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
AU2006252519B2 (en) | 2005-06-02 | 2012-08-30 | Merck Sharp & Dohme Corp. | HCV protease inhibitors in combination with food |
US7608592B2 (en) | 2005-06-30 | 2009-10-27 | Virobay, Inc. | HCV inhibitors |
US7601686B2 (en) | 2005-07-11 | 2009-10-13 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
TWI389908B (zh) | 2005-07-14 | 2013-03-21 | Gilead Sciences Inc | 抗病毒化合物類 |
JP2009501732A (ja) | 2005-07-20 | 2009-01-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | C型肝炎インヒビターペプチド類似体 |
KR101294467B1 (ko) | 2005-07-25 | 2013-09-09 | 인터뮨, 인크. | C형 간염 바이러스 복제의 신규 거대고리형 억제제 |
JO2768B1 (en) | 2005-07-29 | 2014-03-15 | تيبوتيك فارماسيوتيكالز ليمتد | Large cyclic inhibitors of hepatitis C virus |
WO2007030656A1 (en) | 2005-09-09 | 2007-03-15 | Boehringer Ingelheim International Gmbh | Ring-closing metathesis process for the preparation of macrocyclic peptides |
AU2006301966A1 (en) | 2005-10-11 | 2007-04-19 | Array Biopharma, Inc. | Compounds and methods for inhibiting hepatitis C viral replication |
US7772183B2 (en) | 2005-10-12 | 2010-08-10 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US7741281B2 (en) | 2005-11-03 | 2010-06-22 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
EA017448B1 (ru) | 2006-07-13 | 2012-12-28 | Ачиллион Фармасьютикалз, Инк. | 4-амино-4-оксобутаноиловые пептиды как ингибиторы вирусной репликации |
EP1881002A1 (en) | 2006-07-20 | 2008-01-23 | Tibotec Pharmaceuticals Ltd. | HCV NS-3 serine protease inhibitors |
US20100323953A1 (en) | 2007-01-08 | 2010-12-23 | Phenomix Corporation | Macrocyclic hepatitis c protease inhibitors |
WO2008095058A1 (en) | 2007-02-01 | 2008-08-07 | Taigen Biotechnology Co. Ltd. | Hcv protease inhibitors |
NZ592668A (en) | 2008-12-10 | 2013-12-20 | Achillion Pharmaceuticals Inc | New 4-amino-4-oxobutanoyl peptides as inhibitors of viral replication |
TW201329025A (zh) * | 2011-11-01 | 2013-07-16 | Astex Therapeutics Ltd | 醫藥化合物 |
CA2905423A1 (en) | 2013-03-15 | 2014-09-25 | Achillion Pharmaceuticals, Inc. | Sovaprevir tablets |
-
2014
- 2014-03-14 SG SG11201507467VA patent/SG11201507467VA/en unknown
- 2014-03-14 EP EP14717363.7A patent/EP2970192A1/en not_active Withdrawn
- 2014-03-14 BR BR112015023351A patent/BR112015023351A2/pt not_active IP Right Cessation
- 2014-03-14 AU AU2014227849A patent/AU2014227849A1/en not_active Abandoned
- 2014-03-14 WO PCT/US2014/028348 patent/WO2014144087A1/en active Application Filing
- 2014-03-14 KR KR1020157029000A patent/KR20160005686A/ko not_active Application Discontinuation
- 2014-03-14 JP JP2016502765A patent/JP2016513732A/ja active Pending
- 2014-03-14 US US14/211,948 patent/US9227952B2/en not_active Expired - Fee Related
- 2014-03-14 MX MX2015013020A patent/MX2015013020A/es unknown
-
2015
- 2015-09-07 IL IL241290A patent/IL241290A0/en unknown
- 2015-09-14 PH PH12015502122A patent/PH12015502122A1/en unknown
- 2015-11-25 US US14/951,703 patent/US9540346B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2014227849A1 (en) | 2015-10-01 |
IL241290A0 (en) | 2015-11-30 |
US9227952B2 (en) | 2016-01-05 |
KR20160005686A (ko) | 2016-01-15 |
MX2015013020A (es) | 2016-06-10 |
BR112015023351A2 (pt) | 2017-07-18 |
PH12015502122A1 (en) | 2016-01-25 |
WO2014144087A1 (en) | 2014-09-18 |
US20160176847A1 (en) | 2016-06-23 |
US9540346B2 (en) | 2017-01-10 |
EP2970192A1 (en) | 2016-01-20 |
JP2016513732A (ja) | 2016-05-16 |
US20140275163A1 (en) | 2014-09-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1220473A1 (zh) | 抗-α-突觸核蛋白抗體及使用方法 | |
GB2535360B (en) | Methods of preparing polyhemiaminals and polyhexahydrotriazines | |
GB201401248D0 (en) | Method of manufacture | |
GB201312669D0 (en) | Microneedles and method of manufacture | |
HK1224307A1 (zh) | 原毒素- 變體及其使用方法 | |
IL234726A0 (en) | Catheter and its manufacturing method | |
ZA201600927B (en) | Structural assembly and method of assembly thereof | |
SG11201507389RA (en) | Integration of hydro-dechlorination and hydro-regeneration | |
IL241290A0 (en) | Subprevir polymorphs and methods for their production | |
GB201318700D0 (en) | Manufacture of microneedles | |
GB201305231D0 (en) | Method of Manufacture | |
IL246258A0 (en) | Synthesis of an enantiomer of progesterone and its intermediates | |
HK1219650A1 (zh) | 對映黃體酮及其中間產物的合成 | |
PT3022251T (pt) | Compósito e métodos de produção | |
SG11201509753SA (en) | New polymorphic forms of icotinib phosphate and uses thereof | |
HK1216419A1 (zh) | 合成方法 | |
HK1207641A1 (en) | Polymorphic forms of icotinib and uses thereof | |
GB2517189B (en) | Footwear and methods of making footwear | |
GB201304691D0 (en) | Heating means and methods of manufacture | |
IL224391A (en) | Mobile and insulated structure and method of manufacture | |
ZA201508950B (en) | New polymorphic forms of icotinib phosphate and uses thereof | |
GB201311291D0 (en) | Method of manufacture | |
GB201301262D0 (en) | Method of manufacture | |
GB201319281D0 (en) | Bed and method of manufacture thereof | |
PL3071575T3 (pl) | Wytwarzanie normorfinanów |