SG11201505197YA - Insulinotropic peptide derivative with modified n-terminal charge - Google Patents

Insulinotropic peptide derivative with modified n-terminal charge

Info

Publication number
SG11201505197YA
SG11201505197YA SG11201505197YA SG11201505197YA SG11201505197YA SG 11201505197Y A SG11201505197Y A SG 11201505197YA SG 11201505197Y A SG11201505197Y A SG 11201505197YA SG 11201505197Y A SG11201505197Y A SG 11201505197YA SG 11201505197Y A SG11201505197Y A SG 11201505197YA
Authority
SG
Singapore
Prior art keywords
modified
peptide derivative
insulinotropic peptide
terminal charge
charge
Prior art date
Application number
SG11201505197YA
Other languages
English (en)
Inventor
Sung Youb Jung
Sang Youn Hwang
In Young Choi
Sung Hee Park
Se Chang Kwon
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Publication of SG11201505197YA publication Critical patent/SG11201505197YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SG11201505197YA 2013-01-03 2014-01-03 Insulinotropic peptide derivative with modified n-terminal charge SG11201505197YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20130000766 2013-01-03
KR1020140000031A KR20140088837A (ko) 2013-01-03 2014-01-02 Ｎ-말단 전하가 변형된 인슐린 분비 펩티드 유도체
PCT/KR2014/000025 WO2014107035A1 (fr) 2013-01-03 2014-01-03 Dérivé peptidique sécréteur d'insuline à charge n-terminale modifiée

Publications (1)

Publication Number Publication Date
SG11201505197YA true SG11201505197YA (en) 2015-08-28

Family

ID=51737214

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201505197YA SG11201505197YA (en) 2013-01-03 2014-01-03 Insulinotropic peptide derivative with modified n-terminal charge

Country Status (20)

Country Link
US (2) US9663565B2 (fr)
EP (2) EP3281951A1 (fr)
JP (2) JP2016504379A (fr)
KR (1) KR20140088837A (fr)
CN (1) CN104918954A (fr)
AR (1) AR094358A1 (fr)
AU (2) AU2014204193A1 (fr)
BR (1) BR112015016159A2 (fr)
CA (1) CA2896934A1 (fr)
CO (1) CO7461128A2 (fr)
HK (1) HK1211309A1 (fr)
IL (1) IL239795A0 (fr)
MX (1) MX2015008596A (fr)
PH (2) PH12015501491B1 (fr)
RU (1) RU2673179C2 (fr)
SA (1) SA515360713B1 (fr)
SG (1) SG11201505197YA (fr)
TW (1) TW201441253A (fr)
WO (1) WO2014107035A1 (fr)
ZA (1) ZA201505509B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150140177A (ko) 2014-06-05 2015-12-15 한미약품 주식회사 단백질 및 펩타이드의 면역원성을 감소시키는 방법
US20200262887A1 (en) 2018-11-30 2020-08-20 Opko Ireland Global Holdings, Ltd. Oxyntomodulin peptide analog formulations

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04502465A (ja) 1988-12-23 1992-05-07 ノボ　ノルディスク　アクティーゼルスカブ ヒトインシュリン類似物質
JP3728515B2 (ja) * 1994-10-24 2005-12-21 泰信 吉開 医薬組成物
US5688489A (en) * 1995-09-15 1997-11-18 Resolution Pharmaceuticals, Inc. Non-receptor mediated imaging agents
JP2000516912A (ja) 1996-06-05 2000-12-19 ロシュ ダイアグノスティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング エキセンジン類似体、それらの製造方法およびそれらを含有する製剤
PT1019077E (pt) 1997-08-08 2008-02-21 Amylin Pharmaceuticals Inc Novos compostos agonistas de exendina
EP1076066A1 (fr) * 1999-07-12 2001-02-14 Zealand Pharmaceuticals A/S Peptides abaissant le taux de glucose sanguin
IL141647A0 (en) 2001-02-26 2002-03-10 Yeda Res & Dev Synthetic human peptides and pharmaceutical compositions comprising them for the treatment of systemic lupus erythematosus
KR101135244B1 (ko) * 2007-11-29 2012-04-24 한미사이언스 주식회사 인슐린 분비 펩타이드 결합체를 포함하는 비만 관련질환 치료용 조성물
US8263084B2 (en) * 2003-11-13 2012-09-11 Hanmi Science Co., Ltd Pharmaceutical composition for treating obesity-related disease comprising insulinotropic peptide conjugate
EP1817048B1 (fr) * 2004-11-12 2014-02-12 Novo Nordisk A/S Formulations stables de peptides insulinotrophiques
JP2008013452A (ja) * 2006-07-04 2008-01-24 Akira Awaya 医薬組成物
JP2008169195A (ja) 2007-01-05 2008-07-24 Hanmi Pharmaceutical Co Ltd キャリア物質を用いたインスリン分泌ペプチド薬物結合体
JP2009019027A (ja) * 2007-07-16 2009-01-29 Hanmi Pharmaceutical Co Ltd アミノ末端のアミノ酸が変異したインスリン分泌ペプチド誘導体
US20100020445A1 (en) * 2008-07-25 2010-01-28 Brian Thornton Operational-shock performance in a disk drive by maintaining servo signal
WO2010063124A1 (fr) * 2008-12-05 2010-06-10 Angiochem Inc. Conjugués thérapeutiques peptidiques et leurs applications
DE102009007381A1 (de) * 2009-01-29 2010-08-05 Amp-Therapeutics Gmbh & Co. Kg Antibiotische Peptide
EP2408800B1 (fr) * 2009-03-20 2016-05-25 Hanmi Science Co., Ltd. Procédé de préparation d'un conjugué site-spécifié d'un polypeptide physiologiquement actif
UA113626C2 (xx) * 2011-06-02 2017-02-27 Композиція для лікування діабету, що містить кон'югат інсуліну тривалої дії та кон'югат інсулінотропного пептиду тривалої дії

Also Published As

Publication number Publication date
HK1211309A1 (en) 2016-05-20
EP2942358A1 (fr) 2015-11-11
US20170226175A1 (en) 2017-08-10
KR20140088837A (ko) 2014-07-11
JP2016504379A (ja) 2016-02-12
EP3281951A1 (fr) 2018-02-14
CA2896934A1 (fr) 2014-07-10
PH12018501319A1 (en) 2021-02-22
MX2015008596A (es) 2015-09-04
AU2018203300A1 (en) 2018-05-31
CO7461128A2 (es) 2015-11-30
JP2019081777A (ja) 2019-05-30
PH12015501491A1 (en) 2015-09-28
US9663565B2 (en) 2017-05-30
ZA201505509B (en) 2016-07-27
PH12015501491B1 (en) 2015-09-28
BR112015016159A2 (pt) 2017-07-11
RU2673179C2 (ru) 2018-11-22
CN104918954A (zh) 2015-09-16
EP2942358A4 (fr) 2016-06-01
TW201441253A (zh) 2014-11-01
WO2014107035A1 (fr) 2014-07-10
AU2014204193A1 (en) 2015-08-13
SA515360713B1 (ar) 2017-08-13
RU2015129010A (ru) 2017-02-06
AU2018203300B2 (en) 2019-08-15
AR094358A1 (es) 2015-07-29
US20150329611A1 (en) 2015-11-19
IL239795A0 (en) 2015-08-31

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