SG11201503215XA - Novel method for treating spinal cord injury using hmgb1 fragment - Google Patents
Novel method for treating spinal cord injury using hmgb1 fragmentInfo
- Publication number
- SG11201503215XA SG11201503215XA SG11201503215XA SG11201503215XA SG11201503215XA SG 11201503215X A SG11201503215X A SG 11201503215XA SG 11201503215X A SG11201503215X A SG 11201503215XA SG 11201503215X A SG11201503215X A SG 11201503215XA SG 11201503215X A SG11201503215X A SG 11201503215XA
- Authority
- SG
- Singapore
- Prior art keywords
- spinal cord
- novel method
- cord injury
- treating spinal
- hmgb1 fragment
- Prior art date
Links
- 239000012634 fragment Substances 0.000 title 1
- 208000020431 spinal cord injury Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012235786 | 2012-10-25 | ||
| PCT/JP2013/078759 WO2014065348A1 (fr) | 2012-10-25 | 2013-10-24 | Nouveau procédé de traitement d'une lésion de la moelle épinière à l'aide d'un fragment hmgb1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201503215XA true SG11201503215XA (en) | 2015-06-29 |
Family
ID=50544721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201503215XA SG11201503215XA (en) | 2012-10-25 | 2013-10-24 | Novel method for treating spinal cord injury using hmgb1 fragment |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9688733B2 (fr) |
| EP (1) | EP2913059B1 (fr) |
| JP (1) | JP6253590B2 (fr) |
| KR (1) | KR102146822B1 (fr) |
| CN (1) | CN104955470B (fr) |
| AU (1) | AU2013335685B2 (fr) |
| BR (1) | BR112015008745B1 (fr) |
| CA (1) | CA2889299C (fr) |
| DK (1) | DK2913059T3 (fr) |
| ES (1) | ES2673861T3 (fr) |
| HK (2) | HK1212888A1 (fr) |
| MX (1) | MX365899B (fr) |
| PL (1) | PL2913059T3 (fr) |
| RU (1) | RU2649069C2 (fr) |
| SG (1) | SG11201503215XA (fr) |
| TR (1) | TR201807769T4 (fr) |
| WO (1) | WO2014065348A1 (fr) |
| ZA (1) | ZA201502829B (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9919010B2 (en) | 2008-04-30 | 2018-03-20 | Genomix Co., Ltd. | Method for collecting functional cells in vivo with high efficiency |
| PT3358011T (pt) | 2011-04-26 | 2020-04-23 | Univ Osaka | Péptido para induzir a regeneração de um tecido e a sua utilização |
| SG11201503236RA (en) | 2012-10-25 | 2015-06-29 | Genomix Co Ltd | Novel method for treating cardiac infarction using hmgb1 fragment |
| BR112019014921A2 (pt) | 2017-01-27 | 2020-03-31 | StemRIM Inc. | Agente terapêutico para miocardiopatia, infarto antigo do miocárdio e insuficiência cardíaca crônica |
| US11298403B2 (en) | 2017-12-01 | 2022-04-12 | StemRIM Inc. | Therapeutic agent for inflammatory bowel disease |
| WO2019156137A1 (fr) | 2018-02-08 | 2019-08-15 | 株式会社ステムリム | Agent thérapeutique contre le psoriasis |
| BR112021005982A2 (pt) * | 2018-10-05 | 2021-06-29 | StemRIM Inc. | peptídeo possuindo atividade de mobilização de células-tronco mesenquimais |
| CN113423466A (zh) * | 2018-10-25 | 2021-09-21 | 国立大学法人大阪大学 | 软骨病症的治疗剂 |
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| JPS5238680B2 (fr) | 1972-12-27 | 1977-09-30 | ||
| US5658894A (en) | 1989-04-23 | 1997-08-19 | The Trustees Of The University Of Pennsylvania | Compositions for inhibiting restenosis |
| US5661127A (en) | 1995-05-01 | 1997-08-26 | The Regents Of The University Of California | Peptide compositions with growth factor-like activity |
| JP3018313B2 (ja) | 1996-02-23 | 2000-03-13 | 雪印乳業株式会社 | 骨形成促進及び骨吸収防止剤 |
| US20040031072A1 (en) | 1999-05-06 | 2004-02-12 | La Rosa Thomas J. | Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement |
| JP2003505506A (ja) | 1999-07-28 | 2003-02-12 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 幹細胞と前駆細胞のリクルートメントにおけるニコチン受容体アゴニスト |
| EP1114862A3 (fr) | 1999-11-17 | 2003-08-06 | Switch Biotech Aktiengesellschaft | Utilitsation des polypeptides ou leurs acids nucléiques pour la diagnose ou traitement des maladies de la peau et leurs utilisation pour l'identification des substances pharmacologiquement actives |
| DK1257632T3 (da) | 2000-02-24 | 2008-01-28 | Xcyte Therapies Inc | Samtidig stimulering og opkoncentrering af celler |
| JP3421741B2 (ja) | 2000-05-18 | 2003-06-30 | 筑波大学長 | 人工骨髄、血球細胞の増殖方法 |
| US20040191246A1 (en) | 2003-02-26 | 2004-09-30 | Connelly Patrick R. | Process for in vivo treatment of specific biological targets in bodily fluid |
| ITMI20010562A1 (it) | 2001-03-16 | 2002-09-16 | Marco E Bianchi | Inibitori o antagonisti della proteina hmg1 per il trattamento di disordini vascolari |
| DE10121254A1 (de) | 2001-04-30 | 2002-11-07 | Switch Biotech Ag | MRP8/MRP14 Heterodimers oder seiner Einzelkomponenten alleine oder in Kombination zur Behandlung und/oder Prävention von Hauterkrankungen, Wunden und/oder Wundheilungsstörungen, die durch eine verringerte Menge an MRP8/MRP14 Heterodimeren gekennzeichnet sind |
| AU2002304710A1 (en) | 2001-04-30 | 2002-11-11 | Switch Biotech Ag | Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances |
| US7220723B2 (en) | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
| US7304034B2 (en) * | 2001-05-15 | 2007-12-04 | The Feinstein Institute For Medical Research | Use of HMGB fragments as anti-inflammatory agents |
| US20030060410A1 (en) | 2001-05-15 | 2003-03-27 | North Shore Long Island Jewish Research Institute | Use of HMG fragments as anti-inflammatory agents |
| ITMI20011986A1 (it) | 2001-09-25 | 2003-03-25 | San Raffaele Centro Fond | Metodo e composizione per l'attivazione di cellule presentanti l'antigene |
| EP1459759A4 (fr) | 2001-11-19 | 2007-08-29 | Kyowa Hakko Kogyo Kk | Medicament mobilisant les cellules souches totipotentes d'un tissu dans le sang peripherique |
| US20030161816A1 (en) | 2001-12-07 | 2003-08-28 | Fraser John K. | Systems and methods for treating patients with processed lipoaspirate cells |
| CN1671742A (zh) | 2002-07-03 | 2005-09-21 | 塔博尔山圣拉弗尔基金中心 | Hmgb1在治疗组织损伤和/或促进组织修复中的用途 |
| DE60327075D1 (de) | 2002-07-05 | 2009-05-20 | Univ Laval | Der entzündungsreaktionen |
| GB0226251D0 (en) | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
| CA2506328A1 (fr) | 2002-11-20 | 2004-06-03 | Critical Therapeutics, Inc. | Utilisation de fragments hmgb en tant qu'agents anti-inflammatoires |
| US20070154529A1 (en) | 2003-01-03 | 2007-07-05 | Alcedo Biotech Gmbh | Uses of dna binding proteins |
| WO2004084928A1 (fr) | 2003-03-28 | 2004-10-07 | UNIVERSITé LAVAL | Proteine s100 utilisee en tant qu'activateur des neutrophiles pour attenuer la neutropenie dans le traitement du cancer |
| US20050014255A1 (en) | 2003-05-29 | 2005-01-20 | Board Of Regents, The University Of Texas System | Stem cells for clinical and commercial uses |
| WO2005025604A2 (fr) | 2003-09-10 | 2005-03-24 | The General Hospital Corporation | Utilisation de hmgb et fragments de hmgb pour faire diminuer la reponse immunitaire specifique |
| ITRM20040058A1 (it) | 2004-02-03 | 2004-05-03 | Marco E Bianchi | Inibitori ed antagonisti di hmgb1 in grado di regolare la proliferazione delle cellule muscolari lisce ed endoteliali. |
| EP1768693A1 (fr) | 2004-07-20 | 2007-04-04 | Provincia Italiana Della Congregazione Dei Figli Dell'Immacolata Concezione - Istituto Dermopatico Dell'Immacolata | Utilisation de hmgb1 dans la cicatrisation des plaies |
| MX2007001155A (es) | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
| MX2007002557A (es) | 2004-09-03 | 2007-10-10 | Creabilis Therapeutics Spa | Uso de polipeptidos obtenidos a traves de mutaciones sistematicas de aminoacidos unicos de bloque-a humano y no humano de hmgb1 para prevenir y/o antagonizar las patologias inducidas por hmgb1. |
| KR100593397B1 (ko) | 2004-10-27 | 2006-06-28 | 한국원자력연구소 | 중배엽 줄기세포 및/또는 ｐ 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제 |
| WO2006047820A1 (fr) | 2004-11-01 | 2006-05-11 | Newsouth Innovations Pty Limited | Utilisation de la calgranuline a et b pour la stimulation et l'inhibition de la formation de tissus mineralises |
| ITRM20050032A1 (it) | 2005-01-21 | 2006-07-22 | Marco E Bianchi | Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica. |
| JP5103626B2 (ja) | 2005-01-27 | 2012-12-19 | 財団法人ヒューマンサイエンス振興財団 | 間葉系幹細胞を含む細胞シート |
| MX2007011218A (es) | 2005-03-23 | 2007-10-17 | Biosafe Sa | Sistema integrado para colectar, procesar y transplantar subconjuntos de celulas, incluyendo celulas madre adultas para medicina regenerativa. |
| WO2006114805A2 (fr) | 2005-04-28 | 2006-11-02 | Fondazione Centro San Raffaele Del Monte Tabor | Utilisation des proteines hmgb2 et hmgb3 pour applications medicales |
| WO2007015546A1 (fr) | 2005-08-04 | 2007-02-08 | Genomix Co., Ltd | Inducteur de cellules souches mésenchymales, promoteur de régénération tissulaire et méthode de préparation de cellules souches mésenchymales |
| WO2007031100A1 (fr) | 2005-09-14 | 2007-03-22 | Ostini, Marco | Immunothérapie active pour inflammation systémique potentiellement mortelle |
| WO2007130725A2 (fr) | 2006-02-06 | 2007-11-15 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Utilisation de hmgb1 en protection contre les lésions de reperfusion de l'ischémie |
| JP4982739B2 (ja) | 2006-06-01 | 2012-07-25 | 国立大学法人 東京医科歯科大学 | ポリグルタミン病の予防・治療剤 |
| ES2396220T3 (es) | 2006-08-11 | 2013-02-20 | Ono Pharmaceutical Co., Ltd. | Anticuerpos monoclonales frente al factor 1 derivado del estroma (SDF-1) |
| DK2055308T3 (en) | 2006-10-30 | 2017-07-17 | Genomix Co Ltd | PHARMACEUTICALS FOR PROMOTING FUNCTIONAL REGENERATION OF DAMAGED TISSUE |
| US9919010B2 (en) | 2008-04-30 | 2018-03-20 | Genomix Co., Ltd. | Method for collecting functional cells in vivo with high efficiency |
| US8673580B2 (en) | 2008-04-30 | 2014-03-18 | Genomix Co., Ltd. | Agent for recruitment of bone-marrow-derived pluripotent stem cell into peripheral circulation |
| RU2010148785A (ru) * | 2008-04-30 | 2012-06-10 | Дженомикс Ко., Лтд. (Jp) | Фармацевтическое средство для стимуляции функциональной регенерации поврежденной ткани |
| JP2013508013A (ja) * | 2009-10-16 | 2013-03-07 | ザ ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー | 細胞療法戦略を用いた慢性神経組織損傷の治療方法 |
| CN102711777B (zh) | 2009-10-28 | 2015-04-15 | 吉诺米克斯股份有限公司 | 利用骨髓间充质干细胞和/或多能干细胞的血中动员的组织再生促进剂 |
| PT3358011T (pt) | 2011-04-26 | 2020-04-23 | Univ Osaka | Péptido para induzir a regeneração de um tecido e a sua utilização |
| CN102443064A (zh) | 2011-11-03 | 2012-05-09 | 刘誉 | 一种基于凝血酶活性的双靶向作用的嵌合多肽及其应用 |
| SG11201503236RA (en) | 2012-10-25 | 2015-06-29 | Genomix Co Ltd | Novel method for treating cardiac infarction using hmgb1 fragment |
-
2013
- 2013-10-24 ES ES13849823.3T patent/ES2673861T3/es active Active
- 2013-10-24 PL PL13849823T patent/PL2913059T3/pl unknown
- 2013-10-24 WO PCT/JP2013/078759 patent/WO2014065348A1/fr active Application Filing
- 2013-10-24 SG SG11201503215XA patent/SG11201503215XA/en unknown
- 2013-10-24 JP JP2014543335A patent/JP6253590B2/ja active Active
- 2013-10-24 AU AU2013335685A patent/AU2013335685B2/en active Active
- 2013-10-24 CA CA2889299A patent/CA2889299C/fr active Active
- 2013-10-24 RU RU2015119523A patent/RU2649069C2/ru active
- 2013-10-24 MX MX2015005253A patent/MX365899B/es active IP Right Grant
- 2013-10-24 DK DK13849823.3T patent/DK2913059T3/en active
- 2013-10-24 TR TR2018/07769T patent/TR201807769T4/tr unknown
- 2013-10-24 CN CN201380067951.4A patent/CN104955470B/zh active Active
- 2013-10-24 US US14/436,920 patent/US9688733B2/en active Active
- 2013-10-24 KR KR1020157013591A patent/KR102146822B1/ko active IP Right Grant
- 2013-10-24 BR BR112015008745-0A patent/BR112015008745B1/pt active IP Right Grant
- 2013-10-24 EP EP13849823.3A patent/EP2913059B1/fr active Active
-
2015
- 2015-04-24 ZA ZA2015/02829A patent/ZA201502829B/en unknown
-
2016
- 2016-01-25 HK HK16100783.3A patent/HK1212888A1/zh unknown
- 2016-02-04 HK HK16101298.9A patent/HK1213201A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US9688733B2 (en) | 2017-06-27 |
| CN104955470A (zh) | 2015-09-30 |
| TR201807769T4 (tr) | 2018-06-21 |
| ES2673861T3 (es) | 2018-06-26 |
| MX2015005253A (es) | 2015-10-29 |
| BR112015008745A2 (pt) | 2017-11-21 |
| CN104955470B (zh) | 2017-06-16 |
| JPWO2014065348A1 (ja) | 2016-09-08 |
| EP2913059B1 (fr) | 2018-04-11 |
| ZA201502829B (en) | 2020-11-25 |
| HK1213201A1 (zh) | 2016-06-30 |
| JP6253590B2 (ja) | 2017-12-27 |
| EP2913059A1 (fr) | 2015-09-02 |
| WO2014065348A1 (fr) | 2014-05-01 |
| RU2015119523A (ru) | 2016-12-20 |
| MX365899B (es) | 2019-06-19 |
| KR102146822B1 (ko) | 2020-08-21 |
| RU2649069C2 (ru) | 2018-04-02 |
| PL2913059T3 (pl) | 2018-09-28 |
| EP2913059A4 (fr) | 2016-03-30 |
| HK1212888A1 (zh) | 2016-06-24 |
| US20150274792A1 (en) | 2015-10-01 |
| AU2013335685A1 (en) | 2015-05-14 |
| CA2889299A1 (fr) | 2014-05-01 |
| AU2013335685B2 (en) | 2017-10-12 |
| KR20150102957A (ko) | 2015-09-09 |
| DK2913059T3 (en) | 2018-06-25 |
| BR112015008745B1 (pt) | 2022-08-02 |
| CA2889299C (fr) | 2023-02-14 |
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