SG11201501483XA - Drug delivery systems and methods for treatment of prostate disease comprising gemicitabine - Google Patents

Drug delivery systems and methods for treatment of prostate disease comprising gemicitabine

Info

Publication number
SG11201501483XA
SG11201501483XA SG11201501483XA SG11201501483XA SG11201501483XA SG 11201501483X A SG11201501483X A SG 11201501483XA SG 11201501483X A SG11201501483X A SG 11201501483XA SG 11201501483X A SG11201501483X A SG 11201501483XA SG 11201501483X A SG11201501483X A SG 11201501483XA
Authority
SG
Singapore
Prior art keywords
gemicitabine
treatment
methods
drug delivery
delivery systems
Prior art date
Application number
SG11201501483XA
Other languages
English (en)
Inventor
Dennis Giesing
Original Assignee
Taris Biomedical Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taris Biomedical Llc filed Critical Taris Biomedical Llc
Publication of SG11201501483XA publication Critical patent/SG11201501483XA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/04—General characteristics of the apparatus implanted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1078—Urinary tract
    • A61M2210/1085—Bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/16—Male reproductive, genital organs
    • A61M2210/166—Prostate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nanotechnology (AREA)
  • External Artificial Organs (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
SG11201501483XA 2012-08-31 2013-09-03 Drug delivery systems and methods for treatment of prostate disease comprising gemicitabine SG11201501483XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261696029P 2012-08-31 2012-08-31
PCT/US2013/057841 WO2014036556A2 (en) 2012-08-31 2013-09-03 Drug delivery systems and methods for treatment of prostate

Publications (1)

Publication Number Publication Date
SG11201501483XA true SG11201501483XA (en) 2015-03-30

Family

ID=49162284

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201501483XA SG11201501483XA (en) 2012-08-31 2013-09-03 Drug delivery systems and methods for treatment of prostate disease comprising gemicitabine

Country Status (14)

Country Link
US (2) US9636488B2 (ja)
EP (1) EP2890386A2 (ja)
JP (1) JP6309009B2 (ja)
KR (2) KR102383496B1 (ja)
CN (2) CN112516154A (ja)
AU (1) AU2013308465B2 (ja)
BR (1) BR112015004110A2 (ja)
CA (1) CA2882575C (ja)
IL (1) IL237300B (ja)
IN (1) IN2015DN01560A (ja)
MX (1) MX367070B (ja)
RU (1) RU2678308C2 (ja)
SG (1) SG11201501483XA (ja)
WO (1) WO2014036556A2 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102383496B1 (ko) 2012-08-31 2022-04-08 타리스 바이오메디컬 엘엘씨 젬시타빈을 포함하는 전립선 질환의 치료를 위한 약물 전달 시스템과 방법
BR112015003836A2 (pt) 2012-08-31 2017-07-04 Taris Biomedical Llc sistemas e métodos para distribuição de drogas para tratamento de câncer de bexiga
EP3736015B1 (en) 2013-08-19 2023-06-28 TARIS Biomedical LLC Multi-unit drug delivery devices
HRP20221252T1 (hr) * 2014-03-06 2022-12-09 Taris Biomedical Llc Sustavi isporuke lijeka i postupci za liječenje raka mokraćnog mjehura s gemcitabinom
WO2016054472A1 (en) * 2014-10-02 2016-04-07 University Of Maryland, Baltimore Methods of treating pancreatic cancer
EP4209221A1 (en) 2016-05-06 2023-07-12 TARIS Biomedical LLC Method of treating lower tract urothelial cancer
EP3658153A4 (en) 2017-07-25 2021-04-21 TARIS Biomedical LLC METHOD OF TREATMENT OF TUMOR METASTASIS
US10792297B2 (en) 2017-11-08 2020-10-06 Taris Biomedical Llc Methods of treatment and maintenance therapy for bladder cancer using gemcitabine
WO2020028554A1 (en) 2018-08-01 2020-02-06 Taris Biomedical Llc Methods of treating overactive bladder using trospium
US20220107320A1 (en) 2019-02-15 2022-04-07 Incelldx, Inc. Assaying Bladder-Associated Samples, Identifying and Treating Bladder-Associated Neoplasia, and Kits for Use Therein

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171298B1 (en) 1996-05-03 2001-01-09 Situs Corporation Intravesical infuser
JP2006506385A (ja) 2002-10-22 2006-02-23 ザ バイオメリックス コーポレーション 治療剤を小嚢内デリバリーするための方法およびシステム
US8361490B2 (en) * 2004-09-16 2013-01-29 Theracoat Ltd. Biocompatible drug delivery apparatus and methods
DE102005020314A1 (de) * 2005-05-02 2006-11-09 Infineon Technologies Ag Spannungsversorgungsanordnung zur Versorgung einer ersten elektrischen Last und Verfahren zum Bereitstellen einer elektrischen Leistung
US8801694B2 (en) 2005-08-11 2014-08-12 Massachusetts Institute Of Technology Intravesical drug delivery device
EP2012801A4 (en) 2006-04-24 2009-08-05 Gloucester Pharmaceuticals Inc GEMCITABINE COMBINATION THERAPY
EP1913962A1 (en) * 2006-10-22 2008-04-23 Ophir Perelson Expandable medical device for the treatment and prevention of cardiovascular diseases
AU2008205847A1 (en) * 2007-01-19 2008-07-24 Eisai R & D Management Co., Ltd. Composition for treatment of pancreatic cancer
BRPI0820800B8 (pt) 2007-12-11 2021-06-22 Massachusetts Inst Technology dispositivo médico implantável para liberação controlada de droga
MX2010010635A (es) 2008-04-04 2010-12-17 Lipella Pharmaceuticals Inc Tratamiento de la disfuncion de la vejiga usando toxina botulinum liposomal.
JP2011528275A (ja) * 2008-07-17 2011-11-17 ミセル テクノロジーズ，インク． 薬物送達医療デバイス
JP5908279B2 (ja) 2008-08-09 2016-04-26 マサチューセッツ インスチテュート オブ テクノロジーＭａｓｓａｃｈｕｓｅｔｔｓ Ｉｎｓｔｉｔｕｔｅ Ｏｆ Ｔｅｃｈｎｏｌｏｇｙ 移植可能な薬物送達デバイス並びに男性の尿生殖器及び周囲組織を治療する方法
ES2401008T3 (es) 2009-06-26 2013-04-16 Taris Biomedical, Inc. Comprimidos farmacéuticos sólidos para dispositivos implantables para la administración de fármacos
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
US8721621B2 (en) 2009-09-10 2014-05-13 Taris Biomedical, Inc. Systems and methods for deploying devices to genitourinary sites
PT2512581T (pt) 2009-12-17 2021-04-27 Taris Biomedical Inc Dispositivo implantável com tolerabilidade intravesical e métodos de tratamento
ES2732150T3 (es) 2010-01-20 2019-11-20 Urogen Pharma Ltd Material y método para tratar cavidades internas
US20110218488A1 (en) 2010-03-05 2011-09-08 Taris Biomedical, Inc. Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites
EP3795121A1 (en) 2010-08-05 2021-03-24 TARIS Biomedical LLC Ureteral stent drug delivery device
US9457176B2 (en) 2010-10-06 2016-10-04 Taris Biomedical Llc Implantable drug delivery device with bladder retention feature
US8690840B2 (en) 2010-10-06 2014-04-08 Taris Biomedical, Inc. Time-selective bioresorbable or collapsible drug delivery systems and methods
US8979797B2 (en) 2010-12-16 2015-03-17 Ams Research Corporation High pressure delivery system and method for treating pelvic disorder using large molecule therapeutics
ES2943334T3 (es) 2011-01-10 2023-06-12 Taris Biomedical Llc Régimen de lidocaína para el uso de tratamiento sostenido del dolor de vejiga y micción irritativa
BR112013019410A2 (pt) * 2011-02-04 2019-09-24 Taris Biomedical Inc dispositivo implantável para liberação controlada de fármaco de solubilidade baixa
US20150005595A1 (en) 2011-12-30 2015-01-01 Kibur Medical, Inc. Implantable devices and methods for evaluation of active agents
WO2013170069A1 (en) 2012-05-09 2013-11-14 Massachusetts Institute Of Technology Medicament, method, and drug delivery device for treatment of ovarian cancer
BR112015003836A2 (pt) 2012-08-31 2017-07-04 Taris Biomedical Llc sistemas e métodos para distribuição de drogas para tratamento de câncer de bexiga
KR102383496B1 (ko) 2012-08-31 2022-04-08 타리스 바이오메디컬 엘엘씨 젬시타빈을 포함하는 전립선 질환의 치료를 위한 약물 전달 시스템과 방법
AU2013318146B2 (en) 2012-09-18 2018-05-10 Taris Biomedical Llc Drug delivery systems and methods for treatment of bladder voiding dysfunction|and other lower urinary tract disorders by using trospium
CN105209012B (zh) 2013-03-15 2019-02-01 塔里斯生物医药公司 用于药物递送的药物递送装置和方法
KR102398262B1 (ko) 2013-03-15 2022-05-13 타리스 바이오메디컬 엘엘씨 약물-투과성 구성요소를 가지는 약물 전달 장치 및 방법
WO2014169137A1 (en) 2013-04-10 2014-10-16 Massachusetts Institute Of Technology Local drug delivery devices and methods for treating cancer
EP3736015B1 (en) 2013-08-19 2023-06-28 TARIS Biomedical LLC Multi-unit drug delivery devices
HRP20221252T1 (hr) 2014-03-06 2022-12-09 Taris Biomedical Llc Sustavi isporuke lijeka i postupci za liječenje raka mokraćnog mjehura s gemcitabinom

Also Published As

Publication number Publication date
MX367070B (es) 2019-08-05
RU2015109298A (ru) 2016-10-20
MX2015002452A (es) 2015-06-05
US20150165177A1 (en) 2015-06-18
WO2014036556A2 (en) 2014-03-06
EP2890386A2 (en) 2015-07-08
CN112516154A (zh) 2021-03-19
CA2882575C (en) 2020-05-26
US10406335B2 (en) 2019-09-10
CA2882575A1 (en) 2014-03-06
CN104812395A (zh) 2015-07-29
KR102383496B1 (ko) 2022-04-08
IL237300B (en) 2020-02-27
IN2015DN01560A (ja) 2015-07-03
US20170203085A1 (en) 2017-07-20
AU2013308465B2 (en) 2018-05-17
AU2013308465A1 (en) 2015-03-05
US9636488B2 (en) 2017-05-02
JP2015528469A (ja) 2015-09-28
KR20150043508A (ko) 2015-04-22
IL237300A0 (en) 2015-04-30
KR20200120774A (ko) 2020-10-21
JP6309009B2 (ja) 2018-04-11
WO2014036556A3 (en) 2014-04-17
RU2678308C2 (ru) 2019-01-25
BR112015004110A2 (pt) 2017-07-04

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