SG11201408108PA - Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease - Google Patents
Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative diseaseInfo
- Publication number
- SG11201408108PA SG11201408108PA SG11201408108PA SG11201408108PA SG11201408108PA SG 11201408108P A SG11201408108P A SG 11201408108PA SG 11201408108P A SG11201408108P A SG 11201408108PA SG 11201408108P A SG11201408108P A SG 11201408108PA SG 11201408108P A SG11201408108P A SG 11201408108PA
- Authority
- SG
- Singapore
- Prior art keywords
- treating
- pharmaceutical composition
- composition containing
- neurodegenerative disease
- preventing neurodegenerative
- Prior art date
Links
- DCSCXTJOXBUFGB-SFYZADRCSA-N (R)-(+)-verbenone Chemical class CC1=CC(=O)[C@H]2C(C)(C)[C@@H]1C2 DCSCXTJOXBUFGB-SFYZADRCSA-N 0.000 title 1
- 230000004770 neurodegeneration Effects 0.000 title 1
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
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- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/86—Ketones containing a keto group bound to a six-membered aromatic ring containing —CHO groups
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- A—HUMAN NECESSITIES
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- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/03—Organic compounds
- A23L29/055—Organic compounds containing sulfur as heteroatom
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A—HUMAN NECESSITIES
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- A23L35/00—Food or foodstuffs not provided for in groups A23L5/00 – A23L33/00; Preparation or treatment thereof
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A61K31/401—Proline; Derivatives thereof, e.g. captopril
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/402—1-aryl substituted, e.g. piretanide
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
- C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/794—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring
- C07C49/798—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring containing rings other than six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/02—Antioxidant
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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KR20120060314 | 2012-06-05 | ||
PCT/KR2013/004932 WO2013183920A1 (ko) | 2012-06-05 | 2013-06-04 | 베르베논 유도체를 함유하는 퇴행성 뇌질환 치료 또는 예방용 약학 조성물 |
Publications (1)
Publication Number | Publication Date |
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SG11201408108PA true SG11201408108PA (en) | 2015-02-27 |
Family
ID=49712264
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201408108PA SG11201408108PA (en) | 2012-06-05 | 2013-06-04 | Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease |
Country Status (24)
Country | Link |
---|---|
US (2) | US9603842B2 (he) |
EP (1) | EP2857007B1 (he) |
JP (1) | JP5934839B2 (he) |
KR (1) | KR101459612B1 (he) |
CN (2) | CN106977387B (he) |
AU (1) | AU2013272429B2 (he) |
BR (1) | BR112014030325B1 (he) |
CA (1) | CA2875396C (he) |
DK (1) | DK2857007T3 (he) |
ES (1) | ES2673853T3 (he) |
HK (1) | HK1207585A1 (he) |
HU (1) | HUE037638T2 (he) |
IL (1) | IL236112B (he) |
LT (1) | LT2857007T (he) |
MX (1) | MX370180B (he) |
NO (1) | NO2857007T3 (he) |
NZ (2) | NZ718185A (he) |
PL (1) | PL2857007T3 (he) |
PT (1) | PT2857007T (he) |
RU (1) | RU2611349C2 (he) |
SG (1) | SG11201408108PA (he) |
TR (1) | TR201807981T4 (he) |
WO (1) | WO2013183920A1 (he) |
ZA (1) | ZA201408924B (he) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ718185A (en) | 2012-06-05 | 2017-12-22 | Univ Korea Res & Bus Found | Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease |
WO2016122289A2 (ko) * | 2015-01-30 | 2016-08-04 | 고려대학교산학협력단 | 베르베논 유도체를 포함하는 재관류 시술의 부작용을 감소 또는 예방하기 위한 조성물 |
CN107426996B (zh) * | 2015-04-15 | 2019-04-16 | 瓦伦特生物科学有限责任公司 | (s)-2’-乙烯基脱落酸衍生物 |
KR102008995B1 (ko) | 2017-11-10 | 2019-08-08 | 충북대학교 산학협력단 | 산삼 유래 신규 화합물 및 이의 항혈전 용도 |
KR102145416B1 (ko) | 2018-09-11 | 2020-08-19 | 신풍제약 주식회사 | 베르베논 유도체를 포함하는 암 치료 또는 예방용 조성물 |
WO2020101181A1 (ko) | 2018-11-14 | 2020-05-22 | 주식회사 넥스모스 | 압타머를 유효성분으로 포함하는 퇴행성 뇌질환 치료 및 예방용 조성물 |
KR102555329B1 (ko) * | 2020-04-22 | 2023-07-17 | 신풍제약주식회사 | 베르베논 유도체를 포함하는 안구질환의 치료 또는 예방용 약학조성물 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
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US4036884A (en) * | 1971-02-04 | 1977-07-19 | So. Ci. Bre. | Process for the manufacture of a new derivative of alpha-pinene and new medicaments based on this derivative |
SE465649B (sv) | 1989-02-09 | 1991-10-14 | Jan Loefquist | Foerfarande foer bekaempning av den sextandade granbarkborren, pityogenes chalcographus, genom applicering av en inhibitoriskt aktiv maengd av (+) och/eller (-) -verbenon paa gran |
IT1251615B (it) | 1991-10-04 | 1995-05-17 | Golgi Sa | Medicamento ad attivita' antielastasica. |
US6214888B1 (en) * | 1996-09-18 | 2001-04-10 | Applied Genetics Incorporated | Dermatological compounds |
IT1312537B1 (it) | 1999-04-16 | 2002-04-22 | Euphar Group Srl | Derivati del (-)- verbenone. |
EP1261572A4 (en) * | 2000-03-10 | 2004-05-26 | Applied Genetics Inc Dermatics | DERMATOLOGICAL COMPOUNDS |
US20040092583A1 (en) | 2001-01-02 | 2004-05-13 | Elizabeth Shanahan-Prendergast | Treatment for inhibiting neoplastic lesions |
US7270835B2 (en) | 2001-06-20 | 2007-09-18 | Metaproteomics, Llc | Compositions that treat or inhibit pathological conditions associated with inflammatory response |
RU2418577C1 (ru) * | 2009-12-24 | 2011-05-20 | Общество С Ограниченной Ответственностью "Томская Фармацевтическая Фабрика" (Ооо "Тфф") | Средство для лечения болезни паркинсона |
NZ718185A (en) | 2012-06-05 | 2017-12-22 | Univ Korea Res & Bus Found | Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease |
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2013
- 2013-06-04 NZ NZ718185A patent/NZ718185A/en unknown
- 2013-06-04 RU RU2014153571A patent/RU2611349C2/ru active
- 2013-06-04 US US14/405,152 patent/US9603842B2/en active Active
- 2013-06-04 PL PL13800799T patent/PL2857007T3/pl unknown
- 2013-06-04 BR BR112014030325-8A patent/BR112014030325B1/pt active IP Right Grant
- 2013-06-04 JP JP2015515940A patent/JP5934839B2/ja active Active
- 2013-06-04 MX MX2014014929A patent/MX370180B/es active IP Right Grant
- 2013-06-04 ES ES13800799.2T patent/ES2673853T3/es active Active
- 2013-06-04 HU HUE13800799A patent/HUE037638T2/hu unknown
- 2013-06-04 CA CA2875396A patent/CA2875396C/en active Active
- 2013-06-04 DK DK13800799.2T patent/DK2857007T3/en active
- 2013-06-04 KR KR1020130064291A patent/KR101459612B1/ko active IP Right Grant
- 2013-06-04 PT PT138007992T patent/PT2857007T/pt unknown
- 2013-06-04 EP EP13800799.2A patent/EP2857007B1/en active Active
- 2013-06-04 NO NO13800799A patent/NO2857007T3/no unknown
- 2013-06-04 CN CN201710159488.6A patent/CN106977387B/zh active Active
- 2013-06-04 CN CN201380041609.7A patent/CN104768542B/zh active Active
- 2013-06-04 WO PCT/KR2013/004932 patent/WO2013183920A1/ko active Application Filing
- 2013-06-04 TR TR2018/07981T patent/TR201807981T4/tr unknown
- 2013-06-04 AU AU2013272429A patent/AU2013272429B2/en active Active
- 2013-06-04 LT LTEP13800799.2T patent/LT2857007T/lt unknown
- 2013-06-04 SG SG11201408108PA patent/SG11201408108PA/en unknown
- 2013-06-04 NZ NZ702705A patent/NZ702705A/en unknown
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2014
- 2014-12-04 ZA ZA2014/08924A patent/ZA201408924B/en unknown
- 2014-12-07 IL IL236112A patent/IL236112B/he active IP Right Grant
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2015
- 2015-08-27 HK HK15108341.2A patent/HK1207585A1/xx unknown
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2017
- 2017-02-14 US US15/432,522 patent/US10710951B2/en active Active
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