SG11201400974VA - Crystal of 5-hydroxy-1h-imidazole-4-carboxamideˑ3/4 hydrate, method for producing the same and crystal of 5-hydroxy-1h-imidazole-4-carboxamide hydrate - Google Patents
Crystal of 5-hydroxy-1h-imidazole-4-carboxamideˑ3/4 hydrate, method for producing the same and crystal of 5-hydroxy-1h-imidazole-4-carboxamide hydrateInfo
- Publication number
- SG11201400974VA SG11201400974VA SG11201400974VA SG11201400974VA SG11201400974VA SG 11201400974V A SG11201400974V A SG 11201400974VA SG 11201400974V A SG11201400974V A SG 11201400974VA SG 11201400974V A SG11201400974V A SG 11201400974VA SG 11201400974V A SG11201400974V A SG 11201400974VA
- Authority
- SG
- Singapore
- Prior art keywords
- imidazole
- hydroxy
- crystal
- hydrate
- producing
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title 2
- DBVNNOBHULTIHP-UHFFFAOYSA-N 4-hydroxy-1h-imidazole-5-carboxamide;hydrate Chemical compound O.NC(=O)C=1N=CNC=1O DBVNNOBHULTIHP-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011213500 | 2011-09-28 | ||
JP2011213501 | 2011-09-28 | ||
PCT/JP2012/075106 WO2013047758A1 (ja) | 2011-09-28 | 2012-09-28 | 5-ヒドロキシ-1h-イミダゾール-4-カルボキサミド水和物の結晶及び5-ヒドロキシ-1h-イミダゾール-4-カルボキサミド・3/4水和物の結晶及びその製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201400974VA true SG11201400974VA (en) | 2014-09-26 |
Family
ID=47995783
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201400974VA SG11201400974VA (en) | 2011-09-28 | 2012-09-28 | Crystal of 5-hydroxy-1h-imidazole-4-carboxamideˑ3/4 hydrate, method for producing the same and crystal of 5-hydroxy-1h-imidazole-4-carboxamide hydrate |
Country Status (13)
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2762469B1 (en) | 2011-09-28 | 2016-11-23 | FUJIFILM Corporation | Crystal of 5-hydroxy-1h-imidazole-4-carboxamide hydrate, crystal of 5-hydroxy-1h-imidazole-4-carboxamide 3/4 hydrate, and method for producing same |
BR112015015282A2 (pt) * | 2013-01-15 | 2017-07-11 | Fujifilm Corp | sulfato de 5 - hidróxi - 1h - imidazol - 4 - carboxamida |
CA2935905C (en) | 2014-01-10 | 2019-02-05 | Fujifilm Corporation | Method and apparatus for predicting effective dose or sensitivity of 5-hydroxy-1h-imidazole-4-carboxamide, method for determining amount of xanthosine monophosphate, and treatmentagent and method for treating myelodysplastic syndrome |
WO2018051971A1 (ja) * | 2016-09-13 | 2018-03-22 | 富士フイルム株式会社 | Mll関連白血病の予防または治療のための医薬、方法、使用及び化合物 |
WO2019082898A1 (ja) | 2017-10-27 | 2019-05-02 | 富士フイルム株式会社 | 5-ヒドロキシ-1h-イミダゾール-4-カルボキサミド・3/4水和物の製造方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4181731A (en) * | 1976-09-07 | 1980-01-01 | Sumitomo Chemical Company, Limited | Novel therapeutic application of 4-carbamoyl-5-hydroxyimidazole |
JPS5625165A (en) * | 1979-08-08 | 1981-03-10 | Sumitomo Chem Co Ltd | Novel imidazole derivative |
JPS5824569A (ja) * | 1981-08-05 | 1983-02-14 | Sumitomo Chem Co Ltd | イミダゾ−ル誘導体の精製方法 |
US4503235A (en) * | 1983-03-11 | 1985-03-05 | Warner-Lambert Company | Process for producing 4-carbamoyl-1H-imidazolium-5-olate |
JPS60185727A (ja) | 1984-03-05 | 1985-09-21 | Sumitomo Chem Co Ltd | 4−カルバモイルイミダゾリウム−5−オレ−ト製剤の安定化法 |
US5567816A (en) | 1994-07-26 | 1996-10-22 | Syntex (U.S.A.) Inc. | Preparation of acyclovir using 1,3 dioxolane |
CA2152863A1 (en) | 1994-07-26 | 1996-01-27 | Yeun-Kwei Han | Preparation of acyclovir |
WO2002026715A1 (de) | 2000-09-29 | 2002-04-04 | Basf Aktiengesellschaft | Verfahren zur herstellung von 1-substituierten 5-chlor-4methylpyrazolen |
JP2002265601A (ja) | 2001-03-07 | 2002-09-18 | Rikogaku Shinkokai | イミド樹脂 |
CA2597896A1 (en) * | 2005-02-16 | 2006-08-24 | Solvay Pharmaceuticals B.V. | 1h-imidazole derivatives as cannabinoid cb2 receptor modulators |
CN101395141A (zh) * | 2006-02-24 | 2009-03-25 | 莱西肯医药有限公司 | 咪唑基化合物,包含其的组合物和它们的使用方法 |
JP5266010B2 (ja) | 2007-09-14 | 2013-08-21 | 富士フイルム株式会社 | 4−カルバモイル−5−ヒドロキシ−イミダゾール誘導体のスルホン酸塩化合物 |
KR100982720B1 (ko) * | 2008-02-04 | 2010-09-17 | 주식회사 파마코스텍 | 4-카르바모일-1-β-D-리보푸라노실이미다졸륨-5-올레이트의 생산을 위한 중간체로서의 2-아미노말론아미드의제조방법 |
JP5726830B2 (ja) | 2011-09-28 | 2015-06-03 | 富士フイルム株式会社 | 5−ヒドロキシ−1h−イミダゾール−4−カルボキサミド・3/4水和物の結晶及びその製造方法 |
EP2762469B1 (en) | 2011-09-28 | 2016-11-23 | FUJIFILM Corporation | Crystal of 5-hydroxy-1h-imidazole-4-carboxamide hydrate, crystal of 5-hydroxy-1h-imidazole-4-carboxamide 3/4 hydrate, and method for producing same |
-
2012
- 2012-09-28 EP EP12835728.2A patent/EP2762469B1/en not_active Not-in-force
- 2012-09-28 AU AU2012317424A patent/AU2012317424B2/en not_active Ceased
- 2012-09-28 IN IN2346CHN2014 patent/IN2014CN02346A/en unknown
- 2012-09-28 WO PCT/JP2012/075106 patent/WO2013047758A1/ja active Application Filing
- 2012-09-28 RU RU2014111810A patent/RU2630682C2/ru not_active IP Right Cessation
- 2012-09-28 MX MX2014003638A patent/MX354498B/es active IP Right Grant
- 2012-09-28 SG SG11201400974VA patent/SG11201400974VA/en unknown
- 2012-09-28 RU RU2017125796A patent/RU2672560C1/ru not_active IP Right Cessation
- 2012-09-28 BR BR112014007436A patent/BR112014007436A2/pt not_active Application Discontinuation
- 2012-09-28 CN CN201280047308.0A patent/CN103827093B/zh not_active Expired - Fee Related
- 2012-09-28 CA CA2850196A patent/CA2850196A1/en active Pending
- 2012-09-28 KR KR1020147008200A patent/KR101970509B1/ko not_active Expired - Fee Related
-
2014
- 2014-03-24 IL IL231677A patent/IL231677A/en active IP Right Grant
- 2014-03-26 US US14/226,364 patent/US9108928B2/en active Active
-
2015
- 2015-07-10 US US14/796,602 patent/US9567303B2/en not_active Expired - Fee Related
-
2016
- 2016-07-13 IL IL246754A patent/IL246754A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
IL231677A (en) | 2017-01-31 |
AU2012317424A1 (en) | 2014-04-17 |
MX2014003638A (es) | 2014-05-21 |
BR112014007436A2 (pt) | 2017-04-04 |
KR20140069052A (ko) | 2014-06-09 |
EP2762469A1 (en) | 2014-08-06 |
RU2014111810A (ru) | 2015-11-10 |
RU2672560C1 (ru) | 2018-11-16 |
US9108928B2 (en) | 2015-08-18 |
IL246754A (en) | 2017-08-31 |
EP2762469A4 (en) | 2015-01-14 |
US9567303B2 (en) | 2017-02-14 |
WO2013047758A1 (ja) | 2013-04-04 |
IL231677A0 (en) | 2014-05-28 |
AU2012317424B2 (en) | 2017-05-18 |
KR101970509B1 (ko) | 2019-04-19 |
IN2014CN02346A (enrdf_load_stackoverflow) | 2015-06-19 |
US20140275568A1 (en) | 2014-09-18 |
CN103827093B (zh) | 2016-06-15 |
CA2850196A1 (en) | 2013-04-04 |
RU2630682C2 (ru) | 2017-09-12 |
EP2762469B1 (en) | 2016-11-23 |
CN103827093A (zh) | 2014-05-28 |
NZ622928A (en) | 2015-04-24 |
MX354498B (es) | 2018-03-08 |
HK1197406A1 (zh) | 2015-01-16 |
US20150315156A1 (en) | 2015-11-05 |
AU2012317424A8 (en) | 2014-07-03 |
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