SG11201400964PA - Formulations based on solid dispersions - Google Patents

Formulations based on solid dispersions

Info

Publication number
SG11201400964PA
SG11201400964PA SG11201400964PA SG11201400964PA SG11201400964PA SG 11201400964P A SG11201400964P A SG 11201400964PA SG 11201400964P A SG11201400964P A SG 11201400964PA SG 11201400964P A SG11201400964P A SG 11201400964PA SG 11201400964P A SG11201400964P A SG 11201400964PA
Authority
SG
Singapore
Prior art keywords
solid dispersions
formulations based
formulations
dispersions
solid
Prior art date
Application number
SG11201400964PA
Other languages
English (en)
Inventor
Samuel Kyeremateng
Gerd Woehrle
Svenja Warnecke
Simon Kullmann
Ullrich Westedt
Jürgen Weis
Original Assignee
Abbvie Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Deutschland filed Critical Abbvie Deutschland
Publication of SG11201400964PA publication Critical patent/SG11201400964PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
SG11201400964PA 2011-09-26 2012-09-21 Formulations based on solid dispersions SG11201400964PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11182792A EP2572731A1 (de) 2011-09-26 2011-09-26 Formulierungen basierend auf Festdispergierungen
PCT/EP2012/068661 WO2013045365A1 (en) 2011-09-26 2012-09-21 Formulations based on solid dispersions

Publications (1)

Publication Number Publication Date
SG11201400964PA true SG11201400964PA (en) 2014-04-28

Family

ID=46875866

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201400964PA SG11201400964PA (en) 2011-09-26 2012-09-21 Formulations based on solid dispersions

Country Status (15)

Country Link
US (1) US20140296341A1 (de)
EP (2) EP2572731A1 (de)
JP (2) JP2014527976A (de)
KR (1) KR20140069215A (de)
CN (1) CN104039354B (de)
AU (1) AU2012314661B2 (de)
BR (1) BR112014006608A2 (de)
CA (1) CA2847800A1 (de)
CO (1) CO7071123A2 (de)
HK (1) HK1200700A1 (de)
IL (1) IL231384A0 (de)
MX (1) MX2014003673A (de)
RU (1) RU2014116987A (de)
SG (1) SG11201400964PA (de)
WO (1) WO2013045365A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012351948A1 (en) * 2011-12-16 2014-07-10 Allergan, Inc. Ophthalmic compositions comprising polyvinyl capralactam - polyvinyl acetate - polyethylene glycol graft copolymer
DK3091981T3 (da) * 2014-01-09 2021-05-31 Verastem Inc Sammensætninger og fremgangsmåder til behandling af abnorm cellevækst
CN104857515B (zh) * 2014-02-25 2020-01-10 中国科学院上海药物研究所 一种控释给药的药芯组合物以及包含该药芯组合物的渗透泵制剂
CN105769753B (zh) * 2016-04-19 2019-10-29 浙江工业大学 一种温敏凝胶基质及其制备方法与应用
CN106937943A (zh) * 2017-04-20 2017-07-11 上药东英(江苏)药业有限公司 一种培哚普利及其盐的soluplus复合物固体分散体及其制备
SI3644970T1 (sl) * 2017-06-30 2022-05-31 Acrotech Biopharma Llc Nove oralne formulacije belinostata
JPWO2020027011A1 (ja) * 2018-07-30 2021-08-02 中外製薬株式会社 ヒダントイン誘導体の固体分散体
EP3886993A1 (de) * 2018-11-27 2021-10-06 Colgate-Palmolive Company Mundpflegegerät mit einer lösekomponente

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
EP1027886B1 (de) * 1999-02-10 2008-07-09 Pfizer Products Inc. Pharmazeutische feste Dispersionen
US6264981B1 (en) * 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
DE102005053066A1 (de) * 2005-11-04 2007-05-10 Basf Ag Verwendung von Copolymeren als Solubilisatoren für in Wasser schwerlöslichen Verbindungen
WO2008037809A1 (en) * 2006-09-29 2008-04-03 Abbott Gmbh & Co. Kg Transmucosal administration of fibrate compounds and delivery system therefor
CN101765616A (zh) 2007-07-26 2010-06-30 巴斯夫欧洲公司 制备通过接枝聚合在溶液中获得的并基于固体聚醚的共聚物的方法
EP2344138B1 (de) * 2008-09-25 2014-07-16 Basf Se Verwendung von copolymeren auf basis von polyethern und vinylmonomeren als bindemittel für feste wirkstoffhaltige dosierungsformen
US8790703B2 (en) * 2009-03-31 2014-07-29 Basf Se Method for producing preparations of substances poorly soluble in water
WO2010130728A2 (de) * 2009-05-13 2010-11-18 Basf Se Feste pharmazeutischen zubereitungen enthaltend copolymere auf basis von polyethern in kombination mit wasserschwerlöslichen polymeren
WO2011063164A2 (en) * 2009-11-18 2011-05-26 Steady Sleep Rx Co., Inc. Sustained release cannabinoid medicaments
WO2011064111A1 (en) * 2009-11-24 2011-06-03 Basf Se Film-like pharmaceutical dosage forms
EP2536393B1 (de) * 2010-02-18 2014-04-16 AbbVie Deutschland GmbH & Co KG Testsystem zur evaluierung der kompatibilität biologisch aktiver substanzen mit graft copolymeren

Also Published As

Publication number Publication date
MX2014003673A (es) 2014-10-13
JP2014527976A (ja) 2014-10-23
CN104039354A (zh) 2014-09-10
AU2012314661B2 (en) 2017-08-03
BR112014006608A2 (pt) 2017-04-25
AU2012314661A1 (en) 2014-03-20
CN104039354B (zh) 2016-09-21
CO7071123A2 (es) 2014-09-30
CA2847800A1 (en) 2013-04-04
WO2013045365A1 (en) 2013-04-04
NZ621872A (en) 2015-10-30
JP2017200938A (ja) 2017-11-09
US20140296341A1 (en) 2014-10-02
RU2014116987A (ru) 2015-11-10
KR20140069215A (ko) 2014-06-09
HK1200700A1 (en) 2015-08-14
EP2760474A1 (de) 2014-08-06
IL231384A0 (en) 2014-04-30
EP2572731A1 (de) 2013-03-27

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