HK1200700A1 - Formulations based on solid dispersions - Google Patents

Formulations based on solid dispersions

Info

Publication number
HK1200700A1
HK1200700A1 HK15101149.1A HK15101149A HK1200700A1 HK 1200700 A1 HK1200700 A1 HK 1200700A1 HK 15101149 A HK15101149 A HK 15101149A HK 1200700 A1 HK1200700 A1 HK 1200700A1
Authority
HK
Hong Kong
Prior art keywords
solid dispersions
formulations based
formulations
dispersions
solid
Prior art date
Application number
HK15101149.1A
Other languages
English (en)
Chinese (zh)
Inventor
Samuel Kyeremateng
Gerd Woehrle
Svenja Warnecke
Simon Kullmann
Ullrich Westedt
Jrgen Weis
Original Assignee
Abbvie Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Deutschland filed Critical Abbvie Deutschland
Publication of HK1200700A1 publication Critical patent/HK1200700A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK15101149.1A 2011-09-26 2015-02-03 Formulations based on solid dispersions HK1200700A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11182792A EP2572731A1 (de) 2011-09-26 2011-09-26 Formulierungen basierend auf Festdispergierungen
PCT/EP2012/068661 WO2013045365A1 (en) 2011-09-26 2012-09-21 Formulations based on solid dispersions

Publications (1)

Publication Number Publication Date
HK1200700A1 true HK1200700A1 (en) 2015-08-14

Family

ID=46875866

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15101149.1A HK1200700A1 (en) 2011-09-26 2015-02-03 Formulations based on solid dispersions

Country Status (15)

Country Link
US (1) US20140296341A1 (de)
EP (2) EP2572731A1 (de)
JP (2) JP2014527976A (de)
KR (1) KR20140069215A (de)
CN (1) CN104039354B (de)
AU (1) AU2012314661B2 (de)
BR (1) BR112014006608A2 (de)
CA (1) CA2847800A1 (de)
CO (1) CO7071123A2 (de)
HK (1) HK1200700A1 (de)
IL (1) IL231384A0 (de)
MX (1) MX2014003673A (de)
RU (1) RU2014116987A (de)
SG (1) SG11201400964PA (de)
WO (1) WO2013045365A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112014014678A2 (pt) * 2011-12-16 2017-06-13 Allergan Inc composições oftálmicas compreendendo copolímeros de enxertia de polivinil caprolactama-acetato de polivinila-polietileno glicol
MX2016009056A (es) * 2014-01-09 2017-01-23 Verastem Inc Composiciones y metodos para tratamiento de crecimiento celular anormal.
CN104857515B (zh) * 2014-02-25 2020-01-10 中国科学院上海药物研究所 一种控释给药的药芯组合物以及包含该药芯组合物的渗透泵制剂
CN105769753B (zh) * 2016-04-19 2019-10-29 浙江工业大学 一种温敏凝胶基质及其制备方法与应用
CN106937943A (zh) * 2017-04-20 2017-07-11 上药东英(江苏)药业有限公司 一种培哚普利及其盐的soluplus复合物固体分散体及其制备
HRP20220309T1 (hr) * 2017-06-30 2022-05-13 Acrotech Biopharma Llc Nove oralne formulacije belinostata
MX2021001063A (es) * 2018-07-30 2021-04-12 Chugai Pharmaceutical Co Ltd Dispersion solida de derivado de hidantoina.
US20200163446A1 (en) * 2018-11-27 2020-05-28 Colgate-Palmolive Company Oral Care Implement Having a Release Component

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
ATE400252T1 (de) * 1999-02-10 2008-07-15 Pfizer Prod Inc Pharmazeutische feste dispersionen
US6264981B1 (en) * 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
DE102005053066A1 (de) 2005-11-04 2007-05-10 Basf Ag Verwendung von Copolymeren als Solubilisatoren für in Wasser schwerlöslichen Verbindungen
WO2008037809A1 (en) * 2006-09-29 2008-04-03 Abbott Gmbh & Co. Kg Transmucosal administration of fibrate compounds and delivery system therefor
US20100204425A1 (en) 2007-07-26 2010-08-12 Basf Se Process for preparing copolymers obtained by graft polymerization in solution and based on polyethers in solid form
US20110178183A1 (en) * 2008-09-25 2011-07-21 Meyer-Boehm Kathrin Use Of Polyether-Based And Vinyl Monomer-Based Copolymers As Binders For Dosing Forms Comprising Solid Active Ingredients
EP2413907B1 (de) * 2009-03-31 2014-10-01 Basf Se Verfahren zur herstellung von zubereitungen von in wasser schwerlöslichen substanzen
EP2429492B1 (de) * 2009-05-13 2014-06-25 Basf Se Feste pharmazeutische Zubereitungen enthaltend Copolymere auf Basis von Polyethern in Kombination mit wasserschwerlöslichen Polymeren
WO2011063164A2 (en) * 2009-11-18 2011-05-26 Steady Sleep Rx Co., Inc. Sustained release cannabinoid medicaments
EP2504033A1 (de) * 2009-11-24 2012-10-03 Basf Se Filmartige pharmazeutische darreichungsformen
WO2011101352A2 (en) * 2010-02-18 2011-08-25 Abbott Gmbh & Co. Kg Test solvent for evaluating the compatibility of biologically active substances and graft copolymers

Also Published As

Publication number Publication date
SG11201400964PA (en) 2014-04-28
JP2017200938A (ja) 2017-11-09
WO2013045365A1 (en) 2013-04-04
RU2014116987A (ru) 2015-11-10
EP2760474A1 (de) 2014-08-06
BR112014006608A2 (pt) 2017-04-25
CN104039354B (zh) 2016-09-21
CA2847800A1 (en) 2013-04-04
CN104039354A (zh) 2014-09-10
MX2014003673A (es) 2014-10-13
AU2012314661B2 (en) 2017-08-03
CO7071123A2 (es) 2014-09-30
US20140296341A1 (en) 2014-10-02
AU2012314661A1 (en) 2014-03-20
IL231384A0 (en) 2014-04-30
JP2014527976A (ja) 2014-10-23
EP2572731A1 (de) 2013-03-27
KR20140069215A (ko) 2014-06-09
NZ621872A (en) 2015-10-30

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