SG11201400218YA - Methods for increasing osteoblastic function - Google Patents

Methods for increasing osteoblastic function

Info

Publication number
SG11201400218YA
SG11201400218YA SG11201400218YA SG11201400218YA SG11201400218YA SG 11201400218Y A SG11201400218Y A SG 11201400218YA SG 11201400218Y A SG11201400218Y A SG 11201400218YA SG 11201400218Y A SG11201400218Y A SG 11201400218YA SG 11201400218Y A SG11201400218Y A SG 11201400218YA
Authority
SG
Singapore
Prior art keywords
methods
osteoblastic function
increasing osteoblastic
increasing
function
Prior art date
Application number
SG11201400218YA
Other languages
English (en)
Inventor
Silviu Itescu
Ravi Krishnan
Original Assignee
Mesoblast Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mesoblast Inc filed Critical Mesoblast Inc
Publication of SG11201400218YA publication Critical patent/SG11201400218YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0663Bone marrow mesenchymal stem cells (BM-MSC)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201400218YA 2011-09-09 2012-09-07 Methods for increasing osteoblastic function SG11201400218YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161532772P 2011-09-09 2011-09-09
US201161535441P 2011-09-16 2011-09-16
PCT/AU2012/001062 WO2013033777A1 (en) 2011-09-09 2012-09-07 Methods for increasing osteoblastic function

Publications (1)

Publication Number Publication Date
SG11201400218YA true SG11201400218YA (en) 2014-03-28

Family

ID=47831362

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201400218YA SG11201400218YA (en) 2011-09-09 2012-09-07 Methods for increasing osteoblastic function

Country Status (13)

Country Link
US (3) US9642878B2 (zh)
EP (2) EP2753342B1 (zh)
JP (2) JP6363950B2 (zh)
KR (1) KR102009056B1 (zh)
CN (2) CN108635377B (zh)
AU (2) AU2012307086B2 (zh)
CA (1) CA2847575C (zh)
ES (1) ES2676886T3 (zh)
HK (2) HK1197183A1 (zh)
IL (1) IL231327A0 (zh)
SG (1) SG11201400218YA (zh)
TR (1) TR201809635T4 (zh)
WO (1) WO2013033777A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2729562B1 (en) 2011-07-06 2018-04-18 Cell Therapy Limited Progenitor cells of mesodermal lineage
AU2012307086B2 (en) * 2011-09-09 2016-05-26 Mesoblast, Inc. Methods for increasing osteoblastic function
KR20170095932A (ko) * 2014-12-23 2017-08-23 메조블라스트 인터내셔널 에스에이알엘 심부전의 치료 방법
CN110613736A (zh) * 2019-10-30 2019-12-27 广州陈运贤生命科技有限公司 一种用于治疗骨髓衰竭疾病的组合物、制剂及制备方法和应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
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US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
AU8200191A (en) 1990-07-09 1992-02-04 United States of America, as represented by the Secretary, U.S. Department of Commerce, The High efficiency packaging of mutant adeno-associated virus using amber suppressions
US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5226914A (en) 1990-11-16 1993-07-13 Caplan Arnold I Method for treating connective tissue disorders
US5837539A (en) 1990-11-16 1998-11-17 Osiris Therapeutics, Inc. Monoclonal antibodies for human mesenchymal stem cells
DE69233013T2 (de) 1991-08-20 2004-03-04 The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer Adenovirus vermittelter gentransfer in den gastrointestinaltrakt
AU2003901668A0 (en) 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
AUPQ147799A0 (en) 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
DE19939781C2 (de) 1999-08-21 2003-06-18 Schott Glas Skulltiegel für das Erschmelzen oder das Läutern von anorganischen Substanzen, insbesondere von Gläsern und Glaskeramiken
WO2006029347A2 (en) * 2004-09-03 2006-03-16 University Of Maryland, Baltimore Integrin cd18 is a novel stromal stem cell marker and functions to promote osteogenesis
AU2005287855B2 (en) * 2004-09-24 2011-06-16 Mesoblast, Inc. Method of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC)
CN101506355B (zh) * 2004-09-24 2012-06-27 成血管细胞系统公司 多能扩增间充质前体细胞子代(memp)及其应用
ES2654428T3 (es) 2005-04-12 2018-02-13 Mesoblast, Inc. Aislamiento de células multipotenciales adultas por fosfatasa alcalina no específica de tejido
JP2006346420A (ja) 2005-06-13 2006-12-28 Univ Nagoya 移植材料及び骨質改善剤
GB0600972D0 (en) * 2006-01-18 2006-03-01 Univ Leeds Enrichment of cells
EP2089510B1 (en) * 2006-06-28 2021-02-24 The University of Medicine and Dentistry of New Jersey Amnion-derived stem cells and uses thereof
CN101835479A (zh) * 2007-07-25 2010-09-15 佰欧益有限公司 多系祖细胞分化为软骨细胞
KR101688449B1 (ko) 2007-08-06 2016-12-21 메소블라스트, 아이엔씨. 생체 내에서 결합 조직을 생성, 복구 및/또는 유지하는 방법
US7639486B2 (en) * 2007-12-13 2009-12-29 International Business Machines Corporation Rack system providing flexible configuration of computer systems with front access
PL2297304T3 (pl) * 2008-05-07 2018-01-31 Bone Therapeutics Sa Ludzkie komórki kościotwórcze w leczeniu stanów chorobowych i chorób kości związanych z niedoborem odporności lub immunosupresją
US8858932B2 (en) * 2008-06-25 2014-10-14 Mesoblast, Inc. Repair and/or reconstitution of invertebral discs
CN102971414B (zh) * 2009-12-22 2016-01-27 新加坡科技研究局 骨折的治疗
US20120294837A1 (en) * 2010-02-02 2012-11-22 University Of Rochester Methods of isolating and culturing mesenchymal stem cells
US9405700B2 (en) 2010-11-04 2016-08-02 Sonics, Inc. Methods and apparatus for virtualization in an integrated circuit
AU2012307086B2 (en) 2011-09-09 2016-05-26 Mesoblast, Inc. Methods for increasing osteoblastic function

Also Published As

Publication number Publication date
WO2013033777A1 (en) 2013-03-14
HK1259180A1 (zh) 2019-11-29
AU2016219601A1 (en) 2016-09-08
AU2012307086B2 (en) 2016-05-26
JP2017171675A (ja) 2017-09-28
ES2676886T3 (es) 2018-07-25
AU2012307086A1 (en) 2013-05-02
KR102009056B1 (ko) 2019-08-08
HK1197183A1 (zh) 2015-01-09
US11135249B2 (en) 2021-10-05
CN108635377B (zh) 2022-06-24
CA2847575C (en) 2021-10-19
EP2753342A1 (en) 2014-07-16
EP2753342A4 (en) 2015-03-11
CN108635377A (zh) 2018-10-12
EP3351256A1 (en) 2018-07-25
US20170274016A1 (en) 2017-09-28
JP6363950B2 (ja) 2018-07-25
KR20140082660A (ko) 2014-07-02
US20190343887A1 (en) 2019-11-14
JP6444448B2 (ja) 2018-12-26
CN103857401A (zh) 2014-06-11
CA2847575A1 (en) 2013-03-14
JP2014525466A (ja) 2014-09-29
US20140363404A1 (en) 2014-12-11
IL231327A0 (en) 2014-04-30
US9642878B2 (en) 2017-05-09
CN103857401B (zh) 2018-06-05
EP2753342B1 (en) 2018-04-11
TR201809635T4 (tr) 2018-07-23

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