SG11201400218YA - Methods for increasing osteoblastic function - Google Patents

Methods for increasing osteoblastic function

Info

Publication number
SG11201400218YA
SG11201400218YA SG11201400218YA SG11201400218YA SG11201400218YA SG 11201400218Y A SG11201400218Y A SG 11201400218YA SG 11201400218Y A SG11201400218Y A SG 11201400218YA SG 11201400218Y A SG11201400218Y A SG 11201400218YA SG 11201400218Y A SG11201400218Y A SG 11201400218YA
Authority
SG
Singapore
Prior art keywords
methods
osteoblastic function
increasing osteoblastic
increasing
function
Prior art date
Application number
SG11201400218YA
Inventor
Silviu Itescu
Ravi Krishnan
Original Assignee
Mesoblast Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mesoblast Inc filed Critical Mesoblast Inc
Publication of SG11201400218YA publication Critical patent/SG11201400218YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0663Bone marrow mesenchymal stem cells (BM-MSC)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201400218YA 2011-09-09 2012-09-07 Methods for increasing osteoblastic function SG11201400218YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161532772P 2011-09-09 2011-09-09
US201161535441P 2011-09-16 2011-09-16
PCT/AU2012/001062 WO2013033777A1 (en) 2011-09-09 2012-09-07 Methods for increasing osteoblastic function

Publications (1)

Publication Number Publication Date
SG11201400218YA true SG11201400218YA (en) 2014-03-28

Family

ID=47831362

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201400218YA SG11201400218YA (en) 2011-09-09 2012-09-07 Methods for increasing osteoblastic function

Country Status (13)

Country Link
US (3) US9642878B2 (en)
EP (2) EP2753342B1 (en)
JP (2) JP6363950B2 (en)
KR (1) KR102009056B1 (en)
CN (2) CN108635377B (en)
AU (2) AU2012307086B2 (en)
CA (1) CA2847575C (en)
ES (1) ES2676886T3 (en)
HK (2) HK1197183A1 (en)
IL (1) IL231327A0 (en)
SG (1) SG11201400218YA (en)
TR (1) TR201809635T4 (en)
WO (1) WO2013033777A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2729562B1 (en) 2011-07-06 2018-04-18 Cell Therapy Limited Progenitor cells of mesodermal lineage
AU2012307086B2 (en) * 2011-09-09 2016-05-26 Mesoblast, Inc. Methods for increasing osteoblastic function
KR20170095932A (en) * 2014-12-23 2017-08-23 메조블라스트 인터내셔널 에스에이알엘 Method for treating heart failure
CN110613736A (en) * 2019-10-30 2019-12-27 广州陈运贤生命科技有限公司 Composition and preparation for treating bone marrow failure diseases, preparation method and application

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
AU8200191A (en) 1990-07-09 1992-02-04 United States of America, as represented by the Secretary, U.S. Department of Commerce, The High efficiency packaging of mutant adeno-associated virus using amber suppressions
US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5226914A (en) 1990-11-16 1993-07-13 Caplan Arnold I Method for treating connective tissue disorders
US5837539A (en) 1990-11-16 1998-11-17 Osiris Therapeutics, Inc. Monoclonal antibodies for human mesenchymal stem cells
DE69233013T2 (en) 1991-08-20 2004-03-04 The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer ADENOVIRUS MEDIATED GENTRANSFER INTO THE GASTROINTESTINAL TRACT
AU2003901668A0 (en) 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
AUPQ147799A0 (en) 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
DE19939781C2 (en) 1999-08-21 2003-06-18 Schott Glas Skull crucible for melting or refining inorganic substances, especially glasses and glass ceramics
WO2006029347A2 (en) * 2004-09-03 2006-03-16 University Of Maryland, Baltimore Integrin cd18 is a novel stromal stem cell marker and functions to promote osteogenesis
AU2005287855B2 (en) * 2004-09-24 2011-06-16 Mesoblast, Inc. Method of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC)
CN101506355B (en) * 2004-09-24 2012-06-27 成血管细胞系统公司 Multipotential expanded mesenchymal precursor cell progeny (MEMP) and uses thereof
ES2654428T3 (en) 2005-04-12 2018-02-13 Mesoblast, Inc. Isolation of adult multipotential cells by non-tissue alkaline phosphatase
JP2006346420A (en) 2005-06-13 2006-12-28 Univ Nagoya Grafting material and bone improver
GB0600972D0 (en) * 2006-01-18 2006-03-01 Univ Leeds Enrichment of cells
EP2089510B1 (en) * 2006-06-28 2021-02-24 The University of Medicine and Dentistry of New Jersey Amnion-derived stem cells and uses thereof
CN101835479A (en) * 2007-07-25 2010-09-15 佰欧益有限公司 Differentiation of multi-lineage progenitor cells to chondrocytes
KR101688449B1 (en) 2007-08-06 2016-12-21 메소블라스트, 아이엔씨. Methods of generating, repairing and/or maintaining connective tissue in vivo
US7639486B2 (en) * 2007-12-13 2009-12-29 International Business Machines Corporation Rack system providing flexible configuration of computer systems with front access
PL2297304T3 (en) * 2008-05-07 2018-01-31 Bone Therapeutics Sa Human bone-forming cells in the treatment of conditions and bone diseases associated with immunodeficiency or immunosuppression
US8858932B2 (en) * 2008-06-25 2014-10-14 Mesoblast, Inc. Repair and/or reconstitution of invertebral discs
CN102971414B (en) * 2009-12-22 2016-01-27 新加坡科技研究局 The treatment of fracture
US20120294837A1 (en) * 2010-02-02 2012-11-22 University Of Rochester Methods of isolating and culturing mesenchymal stem cells
US9405700B2 (en) 2010-11-04 2016-08-02 Sonics, Inc. Methods and apparatus for virtualization in an integrated circuit
AU2012307086B2 (en) 2011-09-09 2016-05-26 Mesoblast, Inc. Methods for increasing osteoblastic function

Also Published As

Publication number Publication date
WO2013033777A1 (en) 2013-03-14
HK1259180A1 (en) 2019-11-29
AU2016219601A1 (en) 2016-09-08
AU2012307086B2 (en) 2016-05-26
JP2017171675A (en) 2017-09-28
ES2676886T3 (en) 2018-07-25
AU2012307086A1 (en) 2013-05-02
KR102009056B1 (en) 2019-08-08
HK1197183A1 (en) 2015-01-09
US11135249B2 (en) 2021-10-05
CN108635377B (en) 2022-06-24
CA2847575C (en) 2021-10-19
EP2753342A1 (en) 2014-07-16
EP2753342A4 (en) 2015-03-11
CN108635377A (en) 2018-10-12
EP3351256A1 (en) 2018-07-25
US20170274016A1 (en) 2017-09-28
JP6363950B2 (en) 2018-07-25
KR20140082660A (en) 2014-07-02
US20190343887A1 (en) 2019-11-14
JP6444448B2 (en) 2018-12-26
CN103857401A (en) 2014-06-11
CA2847575A1 (en) 2013-03-14
JP2014525466A (en) 2014-09-29
US20140363404A1 (en) 2014-12-11
IL231327A0 (en) 2014-04-30
US9642878B2 (en) 2017-05-09
CN103857401B (en) 2018-06-05
EP2753342B1 (en) 2018-04-11
TR201809635T4 (en) 2018-07-23

Similar Documents

Publication Publication Date Title
DK3505720T3 (en) Cementering under styret tryk
DK3798230T3 (en) Terapeutiske antistoffer
EP2790561A4 (en) Dishmachine
EP2755962A4 (en) Azaindazoles
EP2715659A4 (en) Überfeed
EP2754063A4 (en) Smb2 scaleout
EP2723631A4 (en) Quadfolier
EP2776444A4 (en) Dihydropteridinones
AP2014007621A0 (en) 2-Thiopyrimidinones
GB201117538D0 (en) Methods
EP2695208A4 (en) Micro-thermocouple
HK1259180A1 (en) Method for increasing osteoblastic function
EP2679138A4 (en) Endsoscope
EP2708561A4 (en) Bio-pin
DK2770906T3 (en) Applanationstonometer
EP2684382A4 (en) Earpuff
EP2698098A4 (en) Campimeter
EP2694655A4 (en) pAVEC
EP2702929A4 (en) Campimeter
GB201100001D0 (en) TidySqueeze2
AU4540P (en) BUNNAN Baloskion tetraphyllum
AU5171P (en) Sunparamiho Mandevilla xamabilis
AU5031P (en) BESYS Beschorneria yuccoides
AU5026P (en) Goldstrike Agapanthus inapertus
ZA201206269B (en) Pylon