SG10202009266PA - Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid - Google Patents

Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid

Info

Publication number
SG10202009266PA
SG10202009266PA SG10202009266PA SG10202009266PA SG10202009266PA SG 10202009266P A SG10202009266P A SG 10202009266PA SG 10202009266P A SG10202009266P A SG 10202009266PA SG 10202009266P A SG10202009266P A SG 10202009266PA SG 10202009266P A SG10202009266P A SG 10202009266PA
Authority
SG
Singapore
Prior art keywords
chlorophenoxy
isoquinoline
cyano
carbonyl
hydroxy
Prior art date
Application number
SG10202009266PA
Other languages
English (en)
Inventor
Claudia Witschi
Michael D Thompson
Jung Min Park
Michael P Arend
Original Assignee
Fibrogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50073508&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10202009266P(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fibrogen Inc filed Critical Fibrogen Inc
Publication of SG10202009266PA publication Critical patent/SG10202009266PA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG10202009266PA 2013-01-24 2014-01-23 Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid SG10202009266PA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361756361P 2013-01-24 2013-01-24

Publications (1)

Publication Number Publication Date
SG10202009266PA true SG10202009266PA (en) 2020-10-29

Family

ID=50073508

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202009266PA SG10202009266PA (en) 2013-01-24 2014-01-23 Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid
SG11201505748UA SG11201505748UA (en) 2013-01-24 2014-01-23 Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201505748UA SG11201505748UA (en) 2013-01-24 2014-01-23 Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid

Country Status (15)

Country Link
US (1) US9643928B2 (enrdf_load_stackoverflow)
EP (1) EP2951159B1 (enrdf_load_stackoverflow)
JP (1) JP6437456B2 (enrdf_load_stackoverflow)
KR (1) KR102233081B1 (enrdf_load_stackoverflow)
CN (1) CN105452227B (enrdf_load_stackoverflow)
AU (1) AU2014209319B2 (enrdf_load_stackoverflow)
CA (1) CA2899024C (enrdf_load_stackoverflow)
DK (1) DK2951159T3 (enrdf_load_stackoverflow)
ES (1) ES2694297T3 (enrdf_load_stackoverflow)
IL (1) IL240066B (enrdf_load_stackoverflow)
MX (1) MX360048B (enrdf_load_stackoverflow)
RU (1) RU2666144C2 (enrdf_load_stackoverflow)
SG (2) SG10202009266PA (enrdf_load_stackoverflow)
TW (1) TWI685487B (enrdf_load_stackoverflow)
WO (1) WO2014116849A1 (enrdf_load_stackoverflow)

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DK1644336T3 (da) 2003-06-06 2011-05-09 Fibrogen Inc Nitrogenholdige heteroarylforbindelser og deres anvendelse til forøgelse af endogent erythropoietin
CN105037323A (zh) 2008-11-14 2015-11-11 菲布罗根有限公司 作为hif羟化酶抑制剂的苯并噻喃衍生物
CA2879242C (en) 2012-07-16 2023-05-09 Fibrogen, Inc. Crystalline forms of a prolyl hydroxylase inhibitor [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid
CN106083719B (zh) 2012-07-16 2019-10-18 菲布罗根有限公司 制备异喹啉化合物的方法
US8883823B2 (en) 2012-07-16 2014-11-11 Fibrogen, Inc. Crystalline forms of a prolyl hydroxylase inhibitor
EP2951159B1 (en) 2013-01-24 2018-08-22 Fibrogen, Inc. Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid
CN110448537A (zh) 2013-06-06 2019-11-15 菲布罗根有限公司 Hif羟化酶抑制剂的药物制剂
US10065928B2 (en) 2014-09-02 2018-09-04 Sunshine Lake Pharma Co., Ltd. Quinolinone compound and use thereof
CN115279342A (zh) * 2020-03-17 2022-11-01 兹杜斯生命科学有限公司 包含hif脯氨酰羟化酶抑制剂的制剂

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Also Published As

Publication number Publication date
MX2015009617A (es) 2016-04-20
RU2015134420A (ru) 2017-03-03
AU2014209319B2 (en) 2018-04-19
RU2666144C2 (ru) 2018-09-06
JP6437456B2 (ja) 2018-12-12
MX360048B (es) 2018-10-19
IL240066A0 (en) 2015-09-24
EP2951159A1 (en) 2015-12-09
CA2899024A1 (en) 2014-07-31
IL240066B (en) 2019-08-29
CN105452227A (zh) 2016-03-30
DK2951159T3 (en) 2018-11-19
WO2014116849A1 (en) 2014-07-31
US9643928B2 (en) 2017-05-09
KR20150129679A (ko) 2015-11-20
KR102233081B1 (ko) 2021-03-29
US20160002170A1 (en) 2016-01-07
SG11201505748UA (en) 2015-08-28
HK1217331A1 (en) 2017-01-06
AU2014209319A1 (en) 2015-08-27
ES2694297T3 (es) 2018-12-19
JP2016505071A (ja) 2016-02-18
EP2951159B1 (en) 2018-08-22
CA2899024C (en) 2022-01-04
CN105452227B (zh) 2018-05-29
TWI685487B (zh) 2020-02-21
TW201444800A (zh) 2014-12-01

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