SG10201913222XA - A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site - Google Patents

A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site

Info

Publication number
SG10201913222XA
SG10201913222XA SG10201913222XA SG10201913222XA SG10201913222XA SG 10201913222X A SG10201913222X A SG 10201913222XA SG 10201913222X A SG10201913222X A SG 10201913222XA SG 10201913222X A SG10201913222X A SG 10201913222XA SG 10201913222X A SG10201913222X A SG 10201913222XA
Authority
SG
Singapore
Prior art keywords
composition
residence time
application site
pharmaceutical composition
improved residence
Prior art date
Application number
SG10201913222XA
Other languages
English (en)
Inventor
Jens Hansen
Martin Eduardo Santocildes Romero
Original Assignee
Afyx Therapeutics As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Afyx Therapeutics As filed Critical Afyx Therapeutics As
Publication of SG10201913222XA publication Critical patent/SG10201913222XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
  • Nonwoven Fabrics (AREA)
SG10201913222XA 2015-11-19 2016-11-18 A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site SG10201913222XA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA201570745 2015-11-19

Publications (1)

Publication Number Publication Date
SG10201913222XA true SG10201913222XA (en) 2020-03-30

Family

ID=58718438

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201913222XA SG10201913222XA (en) 2015-11-19 2016-11-18 A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site

Country Status (18)

Country Link
US (4) US20180221295A1 (zh)
EP (1) EP3334412B1 (zh)
JP (2) JP6606279B2 (zh)
KR (3) KR102435996B1 (zh)
CN (1) CN108135833B (zh)
AU (2) AU2016358266B2 (zh)
BR (1) BR112018001978A2 (zh)
CA (1) CA2993377C (zh)
DK (1) DK3334412T3 (zh)
ES (1) ES2900741T3 (zh)
HK (1) HK1256209A1 (zh)
IL (1) IL258093B (zh)
MX (1) MX2018005206A (zh)
MY (1) MY167777A (zh)
NZ (1) NZ740615A (zh)
RU (2) RU2701513C2 (zh)
SG (1) SG10201913222XA (zh)
WO (1) WO2017085264A1 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2019008155A (es) 2017-01-23 2019-11-07 Afyx Therapeutics As Metodo para preparar fibras electrohiladas con un alto contenido de una sustancia bioadhesiva.
JP7162014B2 (ja) 2017-01-23 2022-10-27 アフリックス セラピューティクス アー/エス 電界紡糸繊維に基づく2層生成物の製作方法
WO2021050532A1 (en) * 2019-09-09 2021-03-18 Afyx Therapeutics A/S Compositions for treating fungal infections
WO2021072113A1 (en) 2019-10-08 2021-04-15 Afyx Therapeutics A/S Compositions for the delivery of proteins
EP4108231A1 (en) * 2021-06-25 2022-12-28 Johann-Wolfgang-Goethe-Universität Frankfurt am Main In-situ dissolving electrospun polymer fibers for ocular drug delivery
PL4124336T3 (pl) * 2021-07-30 2024-02-26 Cannamedical Pharma Gmbh Plaster przezśluzówkowy obejmujący kannabinoid i/lub opioid
CA3239200A1 (en) 2021-11-23 2023-06-01 Afyx Development A/S Mucosal patches and methods of use thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61280423A (ja) 1985-06-05 1986-12-11 Kiyuukiyuu Yakuhin Kogyo Kk 口腔内粘膜貼付剤
US6753454B1 (en) * 1999-10-08 2004-06-22 The University Of Akron Electrospun fibers and an apparatus therefor
NZ519992A (en) * 2000-01-28 2004-04-30 Smithkline Beecham Corp Pharmaceutical compositions containing electrospun fiber of polymeric carrier integrated with active agent
US7309498B2 (en) * 2001-10-10 2007-12-18 Belenkaya Bronislava G Biodegradable absorbents and methods of preparation
US20030017208A1 (en) * 2002-07-19 2003-01-23 Francis Ignatious Electrospun pharmaceutical compositions
TW200410714A (en) * 2002-08-07 2004-07-01 Smithkline Beecham Corp Electrospun amorphous pharmaceutical compositions
US20040127978A1 (en) * 2002-08-13 2004-07-01 Medtronic, Inc. Active agent delivery system including a hydrophilic polymer, medical device, and method
US9233080B2 (en) * 2008-03-27 2016-01-12 Agigma, Inc. Compositions and methods for the delivery of agents
WO2013165604A1 (en) * 2012-05-02 2013-11-07 Massachusetts Institute Of Technology Electroprocessing of active pharmaceutical ingredients
CN102670483B (zh) * 2012-05-09 2014-04-02 上海交通大学 一种用于高血脂症治疗的静电纺丝纤维膜制剂及其制备方法
WO2014066297A1 (en) * 2012-10-22 2014-05-01 North Carolina State University Nonwoven fiber materials
EP2810645B1 (en) * 2013-06-06 2017-05-24 A. Sezai Sarac New Drug Delivery System
ES2763524T3 (es) * 2014-06-10 2020-05-29 Afyx Therapeutics As Composiciones que comprenden fibras obtenidas electrohidrodinámicamente para la administración de dosis específicas de una sustancia activa a la piel o la mucosa

Also Published As

Publication number Publication date
US20230285313A1 (en) 2023-09-14
NZ740615A (en) 2019-06-28
RU2018109496A3 (zh) 2019-09-19
KR102435996B1 (ko) 2022-08-25
RU2019129082A (ru) 2020-04-28
RU2018109496A (ru) 2019-09-19
US20190254985A1 (en) 2019-08-22
JP2018528256A (ja) 2018-09-27
EP3334412B1 (en) 2021-10-20
KR20190020173A (ko) 2019-02-27
RU2701513C2 (ru) 2019-09-27
ES2900741T3 (es) 2022-03-18
JP6606279B2 (ja) 2019-11-13
EP3334412A1 (en) 2018-06-20
CA2993377C (en) 2019-11-12
CN108135833B (zh) 2022-11-29
WO2017085264A1 (en) 2017-05-26
AU2018220020C1 (en) 2020-09-17
CN108135833A (zh) 2018-06-08
MY167777A (en) 2018-09-25
JP2020022787A (ja) 2020-02-13
IL258093B (en) 2022-03-01
KR20190067280A (ko) 2019-06-14
DK3334412T3 (da) 2022-01-17
KR102001163B1 (ko) 2019-07-18
BR112018001978A2 (pt) 2018-09-18
HK1256209A1 (zh) 2019-09-13
US20180221295A1 (en) 2018-08-09
CA2993377A1 (en) 2017-05-26
IL258093A (en) 2018-05-31
KR20180040704A (ko) 2018-04-20
AU2018220020A1 (en) 2018-09-06
US20240139117A1 (en) 2024-05-02
AU2016358266B2 (en) 2018-06-21
AU2018220020B2 (en) 2020-05-21
MX2018005206A (es) 2018-08-01
JP6929916B2 (ja) 2021-09-01
AU2016358266A1 (en) 2018-04-05

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