SG10201811116UA - Non-human animals having a humanized programmed cell death 1 gene - Google Patents

Non-human animals having a humanized programmed cell death 1 gene

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Publication number
SG10201811116UA
SG10201811116UA SG10201811116UA SG10201811116UA SG10201811116UA SG 10201811116U A SG10201811116U A SG 10201811116UA SG 10201811116U A SG10201811116U A SG 10201811116UA SG 10201811116U A SG10201811116U A SG 10201811116UA SG 10201811116U A SG10201811116U A SG 10201811116UA
Authority
SG
Singapore
Prior art keywords
human animals
gene
cell death
programmed cell
human
Prior art date
Application number
SG10201811116UA
Other languages
English (en)
Inventor
Elena Burova
Alexander O Mujica
Ka-Man Venus Lai
Andrew J Murphy
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of SG10201811116UA publication Critical patent/SG10201811116UA/en

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    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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SG10201811116UA 2014-06-19 2015-06-19 Non-human animals having a humanized programmed cell death 1 gene SG10201811116UA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462014181P 2014-06-19 2014-06-19
US201462086518P 2014-12-02 2014-12-02
US201562138221P 2015-03-25 2015-03-25

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