SG10201801956SA - Antimicrobial compounds and methods of making and using the same - Google Patents

Antimicrobial compounds and methods of making and using the same

Info

Publication number
SG10201801956SA
SG10201801956SA SG10201801956SA SG10201801956SA SG10201801956SA SG 10201801956S A SG10201801956S A SG 10201801956SA SG 10201801956S A SG10201801956S A SG 10201801956SA SG 10201801956S A SG10201801956S A SG 10201801956SA SG 10201801956S A SG10201801956S A SG 10201801956SA
Authority
SG
Singapore
Prior art keywords
making
methods
same
antimicrobial compounds
antimicrobial
Prior art date
Application number
SG10201801956SA
Other languages
English (en)
Inventor
Zoltan F Kanyo
Ashoke Bhattacharjee
Erin Duffy
Andrea Marra
Original Assignee
Melinta Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melinta Therapeutics Inc filed Critical Melinta Therapeutics Inc
Publication of SG10201801956SA publication Critical patent/SG10201801956SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41881,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG10201801956SA 2013-09-09 2014-09-09 Antimicrobial compounds and methods of making and using the same SG10201801956SA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361875643P 2013-09-09 2013-09-09

Publications (1)

Publication Number Publication Date
SG10201801956SA true SG10201801956SA (en) 2018-04-27

Family

ID=52629046

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201801956SA SG10201801956SA (en) 2013-09-09 2014-09-09 Antimicrobial compounds and methods of making and using the same
SG11201601654TA SG11201601654TA (en) 2013-09-09 2014-09-09 Antimicrobial compunds and methods of making and using the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201601654TA SG11201601654TA (en) 2013-09-09 2014-09-09 Antimicrobial compunds and methods of making and using the same

Country Status (12)

Country Link
US (2) US10106543B2 (es)
EP (1) EP3039025A4 (es)
JP (1) JP2016536338A (es)
KR (1) KR20160070066A (es)
CN (1) CN106103442A (es)
AU (1) AU2014315050A1 (es)
CA (1) CA2923214A1 (es)
IL (1) IL244416A0 (es)
MX (1) MX2016002975A (es)
PH (1) PH12016500453A1 (es)
SG (2) SG10201801956SA (es)
WO (1) WO2015035426A1 (es)

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EP2488502A4 (en) 2009-10-16 2013-05-15 Rib X Pharmaceuticals Inc ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME
JO3078B1 (ar) 2009-11-27 2017-03-15 Janssen Pharmaceutica Nv مورفولينوثيازولات بصفتها منظمات الوستيرية نوع الفا 7 موجبة
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CA2923214A1 (en) 2013-09-09 2015-03-12 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
EA201792006A1 (ru) 2015-03-11 2018-04-30 Мелинта Терапьютикс, Инк. Антимикробные соединения и способы их получения и их применение
MX2018013545A (es) * 2016-05-06 2019-08-14 Melinta Therapeutics Inc Antimicrobianos y metodos de preparacion y uso de los mismos.
WO2017193023A1 (en) * 2016-05-06 2017-11-09 Melinta Therapeutics, Inc. Antimicrobials and methods of making and using same
CA3023317A1 (en) 2016-05-06 2017-11-09 Melinta Therapeutics, Inc. Antimicrobials and methods of making and using same
TW201904970A (zh) * 2017-06-19 2019-02-01 美商梅林塔療法公司 抗微生物劑及製造及使用方法
WO2019164880A1 (en) * 2018-02-21 2019-08-29 Duffy Erin M Antimicrobials and methods of making and using same
US20210253577A1 (en) 2018-06-06 2021-08-19 BioVersys AG Biodefense agents
WO2019234509A2 (en) * 2018-06-06 2019-12-12 BioVersys AG Aminomethylamidine and methylamidine antimicrobial compounds
WO2020115547A2 (en) * 2018-12-07 2020-06-11 BioVersys AG Pyrrolo[2,3-d]pyrimidin-2-one antimicrobial compounds
CN115297930A (zh) * 2019-11-13 2022-11-04 库扎环球有限责任公司 抗微生物化合物和方法

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US9937183B2 (en) 2013-09-09 2018-04-10 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
CA2923214A1 (en) 2013-09-09 2015-03-12 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
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Also Published As

Publication number Publication date
US10106543B2 (en) 2018-10-23
MX2016002975A (es) 2016-10-21
US10815238B2 (en) 2020-10-27
CA2923214A1 (en) 2015-03-12
PH12016500453A1 (en) 2016-05-16
SG11201601654TA (en) 2016-04-28
JP2016536338A (ja) 2016-11-24
CN106103442A (zh) 2016-11-09
EP3039025A4 (en) 2017-05-31
AU2014315050A1 (en) 2016-03-24
EP3039025A1 (en) 2016-07-06
WO2015035426A1 (en) 2015-03-12
KR20160070066A (ko) 2016-06-17
US20190284190A1 (en) 2019-09-19
IL244416A0 (en) 2016-04-21
US20160214988A1 (en) 2016-07-28

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