SG10201705518SA - Age-Related Macular Degeneration Treatment - Google Patents

Age-Related Macular Degeneration Treatment

Info

Publication number
SG10201705518SA
SG10201705518SA SG10201705518SA SG10201705518SA SG10201705518SA SG 10201705518S A SG10201705518S A SG 10201705518SA SG 10201705518S A SG10201705518S A SG 10201705518SA SG 10201705518S A SG10201705518S A SG 10201705518SA SG 10201705518S A SG10201705518S A SG 10201705518SA
Authority
SG
Singapore
Prior art keywords
age
macular degeneration
related macular
degeneration treatment
treatment
Prior art date
Application number
SG10201705518SA
Other languages
English (en)
Inventor
Suhy David
Mao Tin
KAO Shih-Chu
Original Assignee
Benitec Biopharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Benitec Biopharma Ltd filed Critical Benitec Biopharma Ltd
Publication of SG10201705518SA publication Critical patent/SG10201705518SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21047Alternative-complement-pathway C3/C5 convertase (3.4.21.47), i.e. properdin factor B
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • C12N2310/141MicroRNAs, miRNAs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/35Nature of the modification
    • C12N2310/351Conjugate
    • C12N2310/3519Fusion with another nucleic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/50Physical structure
    • C12N2310/53Physical structure partially self-complementary or closed
    • C12N2310/531Stem-loop; Hairpin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00Production
    • C12N2330/50Biochemical production, i.e. in a transformed host cell
    • C12N2330/51Specially adapted vectors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epidemiology (AREA)
SG10201705518SA 2013-01-08 2014-01-08 Age-Related Macular Degeneration Treatment SG10201705518SA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361750086P 2013-01-08 2013-01-08

Publications (1)

Publication Number Publication Date
SG10201705518SA true SG10201705518SA (en) 2017-08-30

Family

ID=51166430

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201705518SA SG10201705518SA (en) 2013-01-08 2014-01-08 Age-Related Macular Degeneration Treatment
SG11201505272QA SG11201505272QA (en) 2013-01-08 2014-01-08 Age-related macular degeneration treatment

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201505272QA SG11201505272QA (en) 2013-01-08 2014-01-08 Age-related macular degeneration treatment

Country Status (13)

Country Link
US (2) US10000753B2 (fr)
EP (1) EP2943571A4 (fr)
JP (1) JP2016507514A (fr)
KR (1) KR20150103280A (fr)
CN (1) CN105143450A (fr)
AU (1) AU2014205036A1 (fr)
CA (1) CA2897342A1 (fr)
HK (1) HK1218656A1 (fr)
IL (1) IL239836A0 (fr)
MX (1) MX2015008697A (fr)
RU (1) RU2015133252A (fr)
SG (2) SG10201705518SA (fr)
WO (1) WO2014107763A1 (fr)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015033343A1 (fr) 2013-09-03 2015-03-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions et procédés utilisables en vue de l'expression de polypeptides recombinés
CA3107872A1 (fr) * 2013-12-12 2015-06-18 Alnylam Pharmaceuticals, Inc. Composition d'arni d'element de complement et procedes pour les utiliser
IL234638A0 (en) 2014-09-14 2014-12-02 Yeda Res & Dev NMDA receptor antagonists for the treatment of Gaucher disease
SG11201703419UA (en) 2014-11-14 2017-05-30 Voyager Therapeutics Inc Modulatory polynucleotides
US10597660B2 (en) 2014-11-14 2020-03-24 Voyager Therapeutics, Inc. Compositions and methods of treating amyotrophic lateral sclerosis (ALS)
EP3273971A4 (fr) 2015-03-27 2018-12-05 Yeda Research and Development Co. Ltd. Méthodes de traitement des maladies des motoneureones
US20180161300A1 (en) 2015-05-11 2018-06-14 Yeda Research And Development Co., Ltd. Citrin inhibitors for the treatment of cancer
KR20210089270A (ko) 2015-07-16 2021-07-15 바이오카인 테라퓨틱스 리미티드 암 치료용 조성물 및 방법
WO2017125931A1 (fr) 2016-01-21 2017-07-27 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Plantes parthénocarpiques et procédés de production de celles-ci
WO2017138008A2 (fr) 2016-02-14 2017-08-17 Yeda Research And Development Co. Ltd. Procédés de modulation de l'exocytose de protéines et utilisations associées en thérapie
US11099185B2 (en) * 2016-02-29 2021-08-24 Maintect Gmbh Predictive markers useful in the treatment of wet age-related macular degeneration
EP3458589A4 (fr) 2016-05-18 2020-01-01 Voyager Therapeutics, Inc. Compositions et méthodes de traitement de la maladie de huntington
KR20240056729A (ko) 2016-05-18 2024-04-30 보이저 테라퓨틱스, 인크. 조절성 폴리뉴클레오티드
IL247368A0 (en) 2016-08-18 2016-11-30 Yeda Res & Dev Diagnostic and therapeutic uses of exosomes
BR112019012312A8 (pt) * 2016-12-14 2023-02-28 Benitec Biopharma Ltd Reagentes para tratamento da distrofia muscular oculofaríngea (opmd) e uso dos mesmos
TW201827596A (zh) * 2016-12-23 2018-08-01 日商協和醱酵麒麟有限公司 抑制補體b因子之表現之核酸
WO2018141025A1 (fr) * 2017-02-03 2018-08-09 Benitec Biopharma Limited Réactifs pour le traitement de maladies ou affections oculaires associées à la néovascularisation, et leur utilisation
JP2020518259A (ja) 2017-05-05 2020-06-25 ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics,Inc. ハンチントン病治療組成物および方法
US11603542B2 (en) 2017-05-05 2023-03-14 Voyager Therapeutics, Inc. Compositions and methods of treating amyotrophic lateral sclerosis (ALS)
IL252151A0 (en) 2017-05-07 2017-07-31 Fainzilber Michael Treatment of stress disorders
WO2019005926A1 (fr) * 2017-06-27 2019-01-03 Massachusetts Eye And Ear Infirmary Édition du génome par aav-crispr/cas9 de vegfr2 pour le traitement de maladies oculaires
IL253642A0 (en) 2017-07-24 2017-09-28 Seger Rony Combined treatment for cancer
SG11202002264RA (en) * 2017-09-15 2020-04-29 Commw Scient Ind Res Org Rna molecules
AU2018336126A1 (en) 2017-09-19 2020-04-30 Tropic Biosciences UK Limited Modifying the specificity of non-coding RNA molecules for silencing gene expression in eukaryotic cells
SG11202002940QA (en) 2017-11-01 2020-04-29 Alnylam Pharmaceuticals Inc Complement component c3 irna compositions and methods of use thereof
IL255664A0 (en) 2017-11-14 2017-12-31 Shachar Idit Hematopoietic stem cells with enhanced properties
IL262658A (en) 2018-10-28 2020-04-30 Memorial Sloan Kettering Cancer Center Prevention of age related clonal hematopoiesis and diseases associated therewith
GB201903521D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd No title
GB201903520D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd Modifying the specificity of non-coding rna molecules for silencing genes in eukaryotic cells
GB201903519D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd Introducing silencing activity to dysfunctional rna molecules and modifying their specificity against a gene of interest
IL268111A (en) 2019-07-16 2021-01-31 Fainzilber Michael Methods of treating pain
WO2021050744A2 (fr) * 2019-09-10 2021-03-18 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Méthodes de traitement de troubles oculaires
IL270306A (en) 2019-10-30 2021-05-31 Yeda Res & Dev Prevention and treatment of pre-myeloid and myeloid malignancies
WO2021152587A1 (fr) 2020-01-30 2021-08-05 Yeda Research And Development Co. Ltd. Traitement d'une maladie hépatique aiguë à l'aide d'inhibiteurs de tlr-mik
WO2022079719A1 (fr) 2020-10-15 2022-04-21 Yeda Research And Development Co. Ltd. Méthode de traitement des cancers myéloïdes
AU2021400235A1 (en) 2020-12-18 2023-07-20 Yeda Research And Development Co. Ltd. Compositions for use in the treatment of chd2 haploinsufficiency and methods of identifying same
EP4267742A2 (fr) 2020-12-28 2023-11-01 1E Therapeutics, Ltd. Arnm de p21 ciblant des dnazymes
KR20230126725A (ko) 2020-12-28 2023-08-30 1이 테라퓨틱스 엘티디. 침묵화를 위한 P21 mRNA 표적 부위
GB202103256D0 (en) 2021-03-09 2021-04-21 Tropic Biosciences Uk Ltd Method for silencing genes
KR20240017813A (ko) 2021-05-10 2024-02-08 이슘 리서치 디벨롭먼트 컴퍼니 오브 더 히브루 유니버시티 오브 예루살렘 엘티디. 신경질환 치료용 약학적 조성물
WO2023031359A1 (fr) * 2021-09-02 2023-03-09 Silence Therapeutics Gmbh Acides nucléiques pour inhiber l'expression du facteur b du complément (cfb) dans une cellule
WO2023062636A1 (fr) 2021-10-14 2023-04-20 Weedout Ltd. Procédés de lutte contre les mauvaises herbes
TW202333749A (zh) 2021-10-29 2023-09-01 美商艾拉倫製藥股份有限公司 補體因子b(cfb)irna組成物及其使用方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7517864B2 (en) * 2001-05-18 2009-04-14 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
US7148342B2 (en) 2002-07-24 2006-12-12 The Trustees Of The University Of Pennyslvania Compositions and methods for sirna inhibition of angiogenesis
US7309487B2 (en) * 2004-02-09 2007-12-18 George Inana Methods and compositions for detecting and treating retinal diseases
AU2005222084B2 (en) * 2004-03-05 2010-04-22 Benitec, Inc. Multiple promoter expression cassettes for simultaneous delivery of RNAI agents
WO2005089224A2 (fr) * 2004-03-12 2005-09-29 Alnylam Pharmaceuticals, Inc. Agents arni ciblant le facteur de croissance de l'endothelium vasculaire (vegf)
US8282921B2 (en) * 2004-08-02 2012-10-09 Paul Glidden tRNA synthetase fragments
EP2172549B1 (fr) 2005-02-03 2015-08-26 Benitec, Inc. Constructions pour l' expression d'ARNi
AU2006239169A1 (en) * 2005-04-28 2006-11-02 Benitec, Limited. Multiple-RNAi expression cassettes for simultaneous delivery of RNAi agents related to heterozygotic expression patterns
EP1951736A4 (fr) * 2005-11-21 2009-12-16 Johnson & Johnson Res Pty Ltd Arns interferents de multiciblage et methodes d'utilisation et de conception
GB0608838D0 (en) 2006-05-04 2006-06-14 Novartis Ag Organic compounds
HUE040417T2 (hu) * 2007-05-04 2019-03-28 Marina Biotech Inc Aminosavlipidek és alkalmazásuk
WO2008154482A2 (fr) * 2007-06-08 2008-12-18 Sirnaomics, Inc. Compositions d'arnsi et procédés d'utilisation dans le traitement de maladies oculaires
WO2009048932A2 (fr) * 2007-10-09 2009-04-16 Children's Medical Center Corporation Procédés pour réguler le traitement d'un arnmi par ciblage de la protéine lin-28
JP5832293B2 (ja) * 2008-12-04 2015-12-16 オプコ ファーマシューティカルズ、エルエルシー 血管新生促進vegfイソ型を選択的に抑制する組成物および方法
RU2013102545A (ru) * 2010-07-28 2014-09-10 Алкон Ресерч, Лтд. Связывающая vegfa си-рнк и способы лечения in vivo
US9220716B2 (en) * 2011-07-26 2015-12-29 Children's Medical Center Corporation Methods and compositions for the treatment of proliferative vascular disorders
CA2899650A1 (fr) 2012-02-29 2013-09-06 Benitec Biopharma Limited Traitement de la douleur

Also Published As

Publication number Publication date
RU2015133252A (ru) 2017-02-10
AU2014205036A1 (en) 2015-07-30
US20180320180A1 (en) 2018-11-08
US10000753B2 (en) 2018-06-19
IL239836A0 (en) 2015-08-31
HK1218656A1 (zh) 2017-03-03
SG11201505272QA (en) 2015-08-28
MX2015008697A (es) 2016-08-04
CA2897342A1 (fr) 2014-07-17
CN105143450A (zh) 2015-12-09
US20160145611A1 (en) 2016-05-26
WO2014107763A1 (fr) 2014-07-17
JP2016507514A (ja) 2016-03-10
EP2943571A4 (fr) 2016-11-30
EP2943571A1 (fr) 2015-11-18
KR20150103280A (ko) 2015-09-09

Similar Documents

Publication Publication Date Title
HK1218656A1 (zh) 年齡相關性黃斑變性治療
HK1222994A1 (zh) 烟草處理
IL266651B (en) graft
HK1217490A1 (zh) 黃斑變性治療中的新穎捕獲劑
HK1217452A1 (zh) 含有前列腺胺的眼内植入物
GB201308131D0 (en) Ophthalmoscope
EP2945639A4 (fr) Procédés de traitement d'états cardiaques
HK1215164A1 (zh) 處理方法
SG10201708547YA (en) Compositions and methods for treating and preventing macular degeneration
GB201304872D0 (en) Treatment
GB201308244D0 (en) Soil treatment
HK1214093A1 (zh) 烟草處理
GB201616158D0 (en) Age-related macular degeneration
HK1216391A1 (zh) 組合治療
PL2826522T3 (pl) Rozrusznik serca
GB201307310D0 (en) Treatment
PT2777699T (pt) Dietilamina-2,5-di-hidroxibenzenossulfonato para o tratamento de degeneração macular relacionada com a idade
GB2514124B (en) Turf Treatment
GB201321115D0 (en) Treatment
GB201309238D0 (en) Treatment
IL230230A0 (en) graft
GB201322764D0 (en) Treating places
GB201310756D0 (en) Implant