SG10201603826UA - Optimizing operating binding capacity for a multiple column chromatography process - Google Patents
Optimizing operating binding capacity for a multiple column chromatography processInfo
- Publication number
- SG10201603826UA SG10201603826UA SG10201603826UA SG10201603826UA SG10201603826UA SG 10201603826U A SG10201603826U A SG 10201603826UA SG 10201603826U A SG10201603826U A SG 10201603826UA SG 10201603826U A SG10201603826U A SG 10201603826UA SG 10201603826U A SG10201603826U A SG 10201603826UA
- Authority
- SG
- Singapore
- Prior art keywords
- column chromatography
- binding capacity
- multiple column
- chromatography process
- optimizing operating
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6034—Construction of the column joining multiple columns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8658—Optimising operation parameters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N2030/382—Flow patterns flow switching in a single column
- G01N2030/385—Flow patterns flow switching in a single column by switching valves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N2030/628—Multiplexing, i.e. several columns sharing a single detector
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/889—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 monitoring the quality of the stationary phase; column performance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/797,785 US11835501B2 (en) | 2015-07-13 | 2015-07-13 | Optimizing operating binding capacity for a multiple column chromatography process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201603826UA true SG10201603826UA (en) | 2017-02-27 |
Family
ID=56080242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201603826UA SG10201603826UA (en) | 2015-07-13 | 2016-05-13 | Optimizing operating binding capacity for a multiple column chromatography process |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11835501B2 (ja) |
| EP (1) | EP3118620B1 (ja) |
| JP (1) | JP6349571B2 (ja) |
| KR (1) | KR101987400B1 (ja) |
| CN (1) | CN106353440B (ja) |
| AU (2) | AU2016203494A1 (ja) |
| CA (1) | CA2930594C (ja) |
| SG (1) | SG10201603826UA (ja) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11835501B2 (en) | 2015-07-13 | 2023-12-05 | Sartorius Stedim Chromatography Systems Ltd. | Optimizing operating binding capacity for a multiple column chromatography process |
| MA44788A (fr) | 2016-04-29 | 2019-03-06 | Nanopareil Llc | Cellulose polymère poreuse préparée par réticulation de cellulose |
| WO2018111832A1 (en) | 2016-12-12 | 2018-06-21 | Nanopareil, Llc | Spinnerets and spinneret arrays for electrospinning and electrospinning machines |
| GB201710130D0 (en) * | 2017-06-26 | 2017-08-09 | Ge Healthcare Bioprocess R & D Ab | A Method of seperation |
| CN108169503B (zh) * | 2018-01-12 | 2024-02-02 | 河北工业大学 | 基于微流控芯片的芳香族挥发性气体快速检测系统 |
| JP7063759B2 (ja) * | 2018-07-25 | 2022-05-09 | 株式会社日立プラントサービス | 精製装置 |
| WO2020059290A1 (ja) * | 2018-09-21 | 2020-03-26 | 株式会社日立ハイテクノロジーズ | 液体クロマトグラフを有する分析装置および液体クロマトグラフの分析方法 |
| CN114072217A (zh) * | 2019-06-28 | 2022-02-18 | 信达生物制药(苏州)有限公司 | 组合式层析装置、无缝连接层析方法和生物制剂的纯化方法 |
| EP3943931A1 (en) * | 2020-07-24 | 2022-01-26 | Tata Consultancy Services Limited | Methods and systems for determining multi-column chromatography process configuration |
| CN112451996B (zh) * | 2020-11-10 | 2021-09-24 | 浙江大学 | 一种多柱连续流层析捕获蛋白的优化方法 |
| KR20230060732A (ko) | 2021-10-28 | 2023-05-08 | 주식회사 제이케이테크 | 빔 프로젝터용 스크린 |
| CN114832439A (zh) * | 2022-06-07 | 2022-08-02 | 杭州奕安济世生物药业有限公司 | 一种自动控制连续层析上样载量的方法和层析方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4802981A (en) | 1987-11-04 | 1989-02-07 | Oros Systems Limited | Automatic chromatography apparatus |
| DE19711083C2 (de) | 1997-03-18 | 1999-04-29 | Sartorius Gmbh | Vorrichtung und Verfahren für die adsorptive Stofftrennung mit Adsorptionsmembranen |
| US6153438A (en) | 1997-04-30 | 2000-11-28 | Hewlett-Packard Company | Retention factor database |
| EP1044378A2 (en) * | 1997-12-31 | 2000-10-18 | Genentech, Inc. | Real-time monitoring of an analyte by chromatography using an on-line assay |
| DE10128546A1 (de) | 2001-06-13 | 2002-12-19 | Merck Patent Gmbh | Verfahren und Vorrichtung zur automatischen, optimierten Durchführung chromatographischer Analysen |
| US6494078B1 (en) | 2001-06-25 | 2002-12-17 | Agilent Technologies, Inc. | Retention-time locked comprehensive multidimensional gas chromatography |
| DE10149256A1 (de) | 2001-10-05 | 2003-04-17 | Merck Patent Gmbh | Alkalistabile hydrophile Sorbentien für die Ionenaustauschchromatographie |
| US6691053B2 (en) | 2001-11-30 | 2004-02-10 | Agilent Technologies, Inc. | Method of matching retention times among multiple chromatographic system |
| US9766217B2 (en) | 2006-09-08 | 2017-09-19 | Novo Nordisk A/S | Methods of optimizing chromatographic separation of polypeptides |
| EP2152405B2 (de) | 2007-05-25 | 2017-04-05 | Merck Patent GmbH | Mischpfropfpolymere für die kationenaustauschchromatographie |
| EP2339339A4 (en) | 2008-09-25 | 2016-10-12 | Jsr Corp | CHARGE FOR AFFINITY CHROMATOGRAPHY |
| EP2370193B1 (en) | 2008-12-04 | 2012-11-14 | Vrije Universiteit Brussel | A chromatographic separation device with variable length and a method for its use |
| US20120091063A1 (en) | 2009-06-26 | 2012-04-19 | Ge Healthcare Bio-Sciences Ab | Method in a chromatography system |
| US9527010B2 (en) | 2009-09-25 | 2016-12-27 | Ge Healthcare Bio-Sciences Corp. | Separation system and method |
| CN102362177B (zh) | 2010-01-26 | 2015-11-25 | 全技术联合公司 | 优化液相色谱系统中的梯度的方法 |
| WO2011147974A1 (en) | 2010-05-28 | 2011-12-01 | Dsm Ip Assets B.V. | Retention time locking for multi-dimensional gas chromatography |
| EP2633306B1 (en) | 2010-10-27 | 2016-03-23 | GE Healthcare Bio-Sciences AB | Chromatography system with guard columns |
| FR2967082B1 (fr) | 2010-11-09 | 2016-12-09 | Nicolas Sebastien Fauquet | Procede de separation par chromatographie continue a haut debit |
| US8802448B2 (en) | 2011-07-27 | 2014-08-12 | Pall Corporation | Mixed mode ligands |
| EP2772466A4 (en) | 2011-10-28 | 2015-12-09 | Agc Si Tech Co Ltd | SPHERICAL BODY BASED ON SILICA AND AFFINITY SUPPORT |
| EP2656892A1 (en) | 2012-04-23 | 2013-10-30 | Merck Patent GmbH | Chromatography method |
| CN102909105A (zh) | 2012-10-31 | 2013-02-06 | 江南大学 | 一种脱除木糖发酵液中盐分的方法及装置 |
| US10099156B2 (en) | 2013-04-08 | 2018-10-16 | Chromacon Ag | Chromatographic purification method |
| US11835501B2 (en) | 2015-07-13 | 2023-12-05 | Sartorius Stedim Chromatography Systems Ltd. | Optimizing operating binding capacity for a multiple column chromatography process |
-
2015
- 2015-07-13 US US14/797,785 patent/US11835501B2/en active Active
-
2016
- 2016-05-13 SG SG10201603826UA patent/SG10201603826UA/en unknown
- 2016-05-13 JP JP2016097202A patent/JP6349571B2/ja active Active
- 2016-05-13 EP EP16169704.0A patent/EP3118620B1/en active Active
- 2016-05-20 CA CA2930594A patent/CA2930594C/en active Active
- 2016-05-27 AU AU2016203494A patent/AU2016203494A1/en not_active Abandoned
- 2016-05-31 KR KR1020160067592A patent/KR101987400B1/ko active IP Right Grant
- 2016-05-31 CN CN201610642206.3A patent/CN106353440B/zh active Active
-
2021
- 2021-09-23 AU AU2021236507A patent/AU2021236507B2/en active Active
-
2023
- 2023-11-10 US US18/506,451 patent/US20240085388A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US11835501B2 (en) | 2023-12-05 |
| KR101987400B1 (ko) | 2019-06-10 |
| CA2930594A1 (en) | 2017-01-13 |
| AU2021236507B2 (en) | 2023-04-13 |
| CN106353440A (zh) | 2017-01-25 |
| KR20170008148A (ko) | 2017-01-23 |
| AU2016203494A1 (en) | 2017-02-02 |
| CN106353440B (zh) | 2019-05-07 |
| US20240085388A1 (en) | 2024-03-14 |
| AU2021236507A1 (en) | 2021-10-28 |
| JP6349571B2 (ja) | 2018-07-04 |
| JP2017049227A (ja) | 2017-03-09 |
| EP3118620B1 (en) | 2024-07-10 |
| EP3118620A1 (en) | 2017-01-18 |
| CA2930594C (en) | 2019-09-03 |
| US20170016864A1 (en) | 2017-01-19 |
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