SG10201603826UA - Optimizing operating binding capacity for a multiple column chromatography process - Google Patents
Optimizing operating binding capacity for a multiple column chromatography processInfo
- Publication number
- SG10201603826UA SG10201603826UA SG10201603826UA SG10201603826UA SG10201603826UA SG 10201603826U A SG10201603826U A SG 10201603826UA SG 10201603826U A SG10201603826U A SG 10201603826UA SG 10201603826U A SG10201603826U A SG 10201603826UA SG 10201603826U A SG10201603826U A SG 10201603826UA
- Authority
- SG
- Singapore
- Prior art keywords
- column chromatography
- binding capacity
- multiple column
- chromatography process
- optimizing operating
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6034—Construction of the column joining multiple columns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8658—Optimising operation parameters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N2030/382—Flow patterns flow switching in a single column
- G01N2030/385—Flow patterns flow switching in a single column by switching valves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N2030/628—Multiplexing, i.e. several columns sharing a single detector
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/889—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 monitoring the quality of the stationary phase; column performance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/797,785 US11835501B2 (en) | 2015-07-13 | 2015-07-13 | Optimizing operating binding capacity for a multiple column chromatography process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201603826UA true SG10201603826UA (en) | 2017-02-27 |
Family
ID=56080242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201603826UA SG10201603826UA (en) | 2015-07-13 | 2016-05-13 | Optimizing operating binding capacity for a multiple column chromatography process |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11835501B2 (en) |
| EP (1) | EP3118620B1 (en) |
| JP (1) | JP6349571B2 (en) |
| KR (1) | KR101987400B1 (en) |
| CN (1) | CN106353440B (en) |
| AU (2) | AU2016203494A1 (en) |
| CA (1) | CA2930594C (en) |
| SG (1) | SG10201603826UA (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11835501B2 (en) | 2015-07-13 | 2023-12-05 | Sartorius Stedim Chromatography Systems Ltd. | Optimizing operating binding capacity for a multiple column chromatography process |
| MA44788A (en) | 2016-04-29 | 2019-03-06 | Nanopareil Llc | POROUS POLYMERIC CELLULOSE PREPARED BY CROSS-LINKING CELLULOSE |
| WO2018111832A1 (en) | 2016-12-12 | 2018-06-21 | Nanopareil, Llc | Spinnerets and spinneret arrays for electrospinning and electrospinning machines |
| GB201710130D0 (en) * | 2017-06-26 | 2017-08-09 | Ge Healthcare Bioprocess R & D Ab | A Method of seperation |
| CN108169503B (en) * | 2018-01-12 | 2024-02-02 | 河北工业大学 | Quick detection system of aromatic volatile gas based on micro-fluidic chip |
| JP7063759B2 (en) * | 2018-07-25 | 2022-05-09 | 株式会社日立プラントサービス | Purifier |
| WO2020059290A1 (en) * | 2018-09-21 | 2020-03-26 | 株式会社日立ハイテクノロジーズ | Analysis device having liquid chromatograph, and liquid chromatograph analysis method |
| CN114072217A (en) * | 2019-06-28 | 2022-02-18 | 信达生物制药(苏州)有限公司 | Combined chromatography device, seamless connection chromatography method and biological agent purification method |
| EP3943931A1 (en) * | 2020-07-24 | 2022-01-26 | Tata Consultancy Services Limited | Methods and systems for determining multi-column chromatography process configuration |
| CN112451996B (en) * | 2020-11-10 | 2021-09-24 | 浙江大学 | Optimization method for capturing protein by multi-column continuous flow chromatography |
| KR20230060732A (en) | 2021-10-28 | 2023-05-08 | 주식회사 제이케이테크 | A beam projector screen |
| CN114832439A (en) * | 2022-06-07 | 2022-08-02 | 杭州奕安济世生物药业有限公司 | Method for automatically controlling sample loading capacity of continuous chromatography and chromatography method |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4802981A (en) | 1987-11-04 | 1989-02-07 | Oros Systems Limited | Automatic chromatography apparatus |
| DE19711083C2 (en) | 1997-03-18 | 1999-04-29 | Sartorius Gmbh | Device and method for adsorptive material separation with adsorption membranes |
| US6153438A (en) | 1997-04-30 | 2000-11-28 | Hewlett-Packard Company | Retention factor database |
| EP1044378A2 (en) * | 1997-12-31 | 2000-10-18 | Genentech, Inc. | Real-time monitoring of an analyte by chromatography using an on-line assay |
| DE10128546A1 (en) | 2001-06-13 | 2002-12-19 | Merck Patent Gmbh | Process for automatically carrying out chromatographic investigations comprises acquiring data, calculating retention times, optimizing retention times |
| US6494078B1 (en) | 2001-06-25 | 2002-12-17 | Agilent Technologies, Inc. | Retention-time locked comprehensive multidimensional gas chromatography |
| DE10149256A1 (en) | 2001-10-05 | 2003-04-17 | Merck Patent Gmbh | Alkali stable hydrophilic sorbents, useful for ion exchange chromatography for the separation of e.g. biopolymers, peptides, and nucleic acids, obtained from a base material containing diol groups and by graft polymerization |
| US6691053B2 (en) | 2001-11-30 | 2004-02-10 | Agilent Technologies, Inc. | Method of matching retention times among multiple chromatographic system |
| US9766217B2 (en) | 2006-09-08 | 2017-09-19 | Novo Nordisk A/S | Methods of optimizing chromatographic separation of polypeptides |
| EP2152405B2 (en) | 2007-05-25 | 2017-04-05 | Merck Patent GmbH | Graft copolymer for cation-exchange chromatography |
| EP2339339A4 (en) | 2008-09-25 | 2016-10-12 | Jsr Corp | Filler for affinity chromatography |
| EP2370193B1 (en) | 2008-12-04 | 2012-11-14 | Vrije Universiteit Brussel | A chromatographic separation device with variable length and a method for its use |
| US20120091063A1 (en) | 2009-06-26 | 2012-04-19 | Ge Healthcare Bio-Sciences Ab | Method in a chromatography system |
| US9527010B2 (en) | 2009-09-25 | 2016-12-27 | Ge Healthcare Bio-Sciences Corp. | Separation system and method |
| CN102362177B (en) | 2010-01-26 | 2015-11-25 | 全技术联合公司 | Optimize the method for the gradient in liquid chromatographic system |
| WO2011147974A1 (en) | 2010-05-28 | 2011-12-01 | Dsm Ip Assets B.V. | Retention time locking for multi-dimensional gas chromatography |
| EP2633306B1 (en) | 2010-10-27 | 2016-03-23 | GE Healthcare Bio-Sciences AB | Chromatography system with guard columns |
| FR2967082B1 (en) | 2010-11-09 | 2016-12-09 | Nicolas Sebastien Fauquet | METHOD FOR HIGH-FLOW CONTINUOUS CHROMATOGRAPHY SEPARATION |
| US8802448B2 (en) | 2011-07-27 | 2014-08-12 | Pall Corporation | Mixed mode ligands |
| EP2772466A4 (en) | 2011-10-28 | 2015-12-09 | Agc Si Tech Co Ltd | Silica spherical body and affinity carrier |
| EP2656892A1 (en) | 2012-04-23 | 2013-10-30 | Merck Patent GmbH | Chromatography method |
| CN102909105A (en) | 2012-10-31 | 2013-02-06 | 江南大学 | Method and device for removing salt in xylose fermentation liquor |
| US10099156B2 (en) | 2013-04-08 | 2018-10-16 | Chromacon Ag | Chromatographic purification method |
| US11835501B2 (en) | 2015-07-13 | 2023-12-05 | Sartorius Stedim Chromatography Systems Ltd. | Optimizing operating binding capacity for a multiple column chromatography process |
-
2015
- 2015-07-13 US US14/797,785 patent/US11835501B2/en active Active
-
2016
- 2016-05-13 SG SG10201603826UA patent/SG10201603826UA/en unknown
- 2016-05-13 JP JP2016097202A patent/JP6349571B2/en active Active
- 2016-05-13 EP EP16169704.0A patent/EP3118620B1/en active Active
- 2016-05-20 CA CA2930594A patent/CA2930594C/en active Active
- 2016-05-27 AU AU2016203494A patent/AU2016203494A1/en not_active Abandoned
- 2016-05-31 KR KR1020160067592A patent/KR101987400B1/en active IP Right Grant
- 2016-05-31 CN CN201610642206.3A patent/CN106353440B/en active Active
-
2021
- 2021-09-23 AU AU2021236507A patent/AU2021236507B2/en active Active
-
2023
- 2023-11-10 US US18/506,451 patent/US20240085388A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US11835501B2 (en) | 2023-12-05 |
| KR101987400B1 (en) | 2019-06-10 |
| CA2930594A1 (en) | 2017-01-13 |
| AU2021236507B2 (en) | 2023-04-13 |
| CN106353440A (en) | 2017-01-25 |
| KR20170008148A (en) | 2017-01-23 |
| AU2016203494A1 (en) | 2017-02-02 |
| CN106353440B (en) | 2019-05-07 |
| US20240085388A1 (en) | 2024-03-14 |
| AU2021236507A1 (en) | 2021-10-28 |
| JP6349571B2 (en) | 2018-07-04 |
| JP2017049227A (en) | 2017-03-09 |
| EP3118620B1 (en) | 2024-07-10 |
| EP3118620A1 (en) | 2017-01-18 |
| CA2930594C (en) | 2019-09-03 |
| US20170016864A1 (en) | 2017-01-19 |
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