SG10201406651PA - A pharmaceutical composition for treating cancer comprising trypsinogen and/orchymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compoundand a cytoplasmic glycolysis reduction agent - Google Patents

A pharmaceutical composition for treating cancer comprising trypsinogen and/orchymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compoundand a cytoplasmic glycolysis reduction agent

Info

Publication number
SG10201406651PA
SG10201406651PA SG10201406651PA SG10201406651PA SG10201406651PA SG 10201406651P A SG10201406651P A SG 10201406651PA SG 10201406651P A SG10201406651P A SG 10201406651PA SG 10201406651P A SG10201406651P A SG 10201406651PA SG 10201406651P A SG10201406651P A SG 10201406651PA
Authority
SG
Singapore
Prior art keywords
orchymotrypsinogen
compoundand
trypsinogen
vanilloid
pharmaceutical composition
Prior art date
Application number
SG10201406651PA
Other languages
English (en)
Inventor
Julian Norman Kenyon
Paul Rodney Clayton
David Tosh
Fernando Felquer
Ralf Brandt
Original Assignee
Propanc Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009905147A external-priority patent/AU2009905147A0/en
Application filed by Propanc Pty Ltd filed Critical Propanc Pty Ltd
Publication of SG10201406651PA publication Critical patent/SG10201406651PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4826Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
SG10201406651PA 2009-10-22 2010-10-22 A pharmaceutical composition for treating cancer comprising trypsinogen and/orchymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compoundand a cytoplasmic glycolysis reduction agent SG10201406651PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2009905147A AU2009905147A0 (en) 2009-10-22 Pharmaceutical Compositions
AU2010902655A AU2010902655A0 (en) 2010-06-17 Cancer Cell Regulation

Publications (1)

Publication Number Publication Date
SG10201406651PA true SG10201406651PA (en) 2014-11-27

Family

ID=43899732

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201406651PA SG10201406651PA (en) 2009-10-22 2010-10-22 A pharmaceutical composition for treating cancer comprising trypsinogen and/orchymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compoundand a cytoplasmic glycolysis reduction agent

Country Status (22)

Country Link
US (4) US9636359B2 (fr)
EP (2) EP3095458B1 (fr)
JP (1) JP5871805B2 (fr)
KR (1) KR101936439B1 (fr)
CN (2) CN107625957B (fr)
AU (1) AU2010310887B9 (fr)
BR (1) BR112012009521B1 (fr)
CA (1) CA2814958C (fr)
CL (1) CL2012001019A1 (fr)
DK (1) DK3095458T3 (fr)
ES (1) ES2692377T3 (fr)
HK (1) HK1249017A1 (fr)
IL (1) IL219216A (fr)
MX (1) MX355971B (fr)
NZ (1) NZ599996A (fr)
PE (1) PE20121709A1 (fr)
PT (1) PT3095458T (fr)
RU (1) RU2012120785A (fr)
SG (1) SG10201406651PA (fr)
TR (1) TR201815315T4 (fr)
WO (1) WO2011047434A1 (fr)
ZA (1) ZA201203689B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107625957B (zh) 2009-10-22 2021-06-15 普罗潘克股份有限公司 包含胰蛋白酶原和糜蛋白酶原的用于治疗癌的药物组合物
CN114533753A (zh) * 2013-03-15 2022-05-27 全技术公司 含硒组合物及其治疗和预防与线粒体功能障碍有关的疾病或病症的应用
CZ307195B6 (cs) 2013-11-18 2018-03-14 František Trnka Farmaceutická kompozice obsahující směs proenzymů a enzymů
US10201559B2 (en) * 2014-03-14 2019-02-12 Alltech, Inc. Compositions of selenoorganic compounds and methods of use thereof
US10092550B2 (en) 2014-10-21 2018-10-09 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof
US20160106722A1 (en) 2014-10-21 2016-04-21 Life Plus, LLC Human therapeutic agents
US9907786B2 (en) 2014-10-21 2018-03-06 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof
CA3003835A1 (fr) * 2015-11-12 2017-05-18 Propanc Pty Ltd Composition de proenzyme
NZ744845A (en) 2016-01-29 2023-04-28 Propanc Pty Ltd Cancer treatment
JP7004665B2 (ja) * 2016-04-12 2022-02-04 プロパンク・ピーティーワイ・リミテッド 癌治療用の前酵素の組成物
EP3517117A1 (fr) * 2018-01-30 2019-07-31 Medizinische Universität Wien Médicament pour la prévention ou le traitement d'une infection par rhinovirus
WO2022261440A1 (fr) * 2021-06-11 2022-12-15 Sorrento Therapeutics, Inc. Administration de résinifératoxine pour le traitement du cancer du pancréas

Family Cites Families (21)

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US4514388A (en) * 1983-03-22 1985-04-30 Psaledakis Nicholas G Proteolytic enzymes in the zymogen form to treat sarcoma cells
US4978332A (en) * 1987-09-28 1990-12-18 Matrix Pharmaceutical, Inc. Treatments employing vasoconstrictive substances in combination with cytotoxic agents for introduction into cellular lesion areas
US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
FR2727107B1 (fr) * 1994-11-21 1996-12-27 Saint Gobain Vitrage Vitrage muni d'au moins une couche mince et son procede d'obtention
CZ283972B6 (cs) * 1995-05-17 1998-07-15 František Mudr. Trnka Farmaceutický prostředek s modulačním účinkem na zhoubné nádory a jeho použití
CN1121218C (zh) * 2000-03-08 2003-09-17 台湾东洋药品工业股份有限公司 酞胺哌啶酮在治疗肝细胞癌的药物组合物中的应用
US6670330B1 (en) * 2000-05-01 2003-12-30 Theodore J. Lampidis Cancer chemotherapy with 2-deoxy-D-glucose
WO2002056823A2 (fr) * 2001-01-18 2002-07-25 Arnold Hoffman Therapie par oxydoreduction pour des tumeurs
CN1471925A (zh) * 2002-08-02 2004-02-04 丛繁滋 更适于硬质肿瘤直接给药的含砷组合物、制剂及制备方法
JP2004182674A (ja) * 2002-12-05 2004-07-02 Kureha Chem Ind Co Ltd バニリル脂肪酸アミドを含む抗腫瘍医薬組成物
CA2513399A1 (fr) * 2003-01-10 2004-07-29 Threshold Pharmaceuticals, Inc. Traitement du cancer par le 2-desoxyglucose
CA2525277A1 (fr) * 2003-05-13 2004-12-02 Health Research Inc. Procede pour augmenter l'activite antitumorale d'agents anticancereux
DE10321725A1 (de) * 2003-05-14 2004-12-02 Mucos Pharma Gmbh & Co Enzymhaltige Zusammensetzungen, daraus hergestellte diätetische Lebensmittel und Arzneimittel und ihre Verwendung für medizinische Zwecke
CN1557482A (zh) * 2004-02-04 2004-12-29 高春平 调节免疫功能、抗肿瘤的天然营养剂
JP2006151965A (ja) * 2004-10-28 2006-06-15 Mi Tec:Kk セレン含有組成物及びその製法
WO2006126067A1 (fr) * 2005-05-26 2006-11-30 Council Of Scientific And Industrial Research Composition pharmaceutique utile pour le traitement du carcinome hepatocellulaire
KR100740989B1 (ko) * 2005-07-22 2007-07-19 넨시스(주) 구형 항염·항암효소 과립제 및 이의 제조방법
CN1944641B (zh) * 2006-10-26 2010-11-03 上海林叶生物科技有限公司 高纯度糜蛋白酶的制备方法
WO2009061051A1 (fr) * 2007-11-09 2009-05-14 Catholic University Industry Academic Cooperation Foundation Nouvelle utilisation du capsiate ou du dihydrocapsiate
CN107625957B (zh) 2009-10-22 2021-06-15 普罗潘克股份有限公司 包含胰蛋白酶原和糜蛋白酶原的用于治疗癌的药物组合物
CZ307195B6 (cs) * 2013-11-18 2018-03-14 František Trnka Farmaceutická kompozice obsahující směs proenzymů a enzymů

Also Published As

Publication number Publication date
US20190388463A1 (en) 2019-12-26
AU2010310887B2 (en) 2015-09-03
HK1249017A1 (zh) 2018-10-26
EP2490711A4 (fr) 2013-04-03
RU2012120785A (ru) 2013-11-27
CA2814958A1 (fr) 2011-04-28
CN102639145B (zh) 2017-09-26
AU2010310887B9 (en) 2015-10-08
BR112012009521B1 (pt) 2021-07-13
ZA201203689B (en) 2013-02-27
IL219216A (en) 2017-03-30
US20230137573A1 (en) 2023-05-04
NZ599996A (en) 2014-06-27
AU2010310887A1 (en) 2012-06-07
TR201815315T4 (tr) 2018-11-21
CA2814958C (fr) 2023-09-26
US20180064753A1 (en) 2018-03-08
DK3095458T3 (en) 2018-11-19
US10350239B2 (en) 2019-07-16
CN107625957B (zh) 2021-06-15
US9636359B2 (en) 2017-05-02
JP5871805B2 (ja) 2016-03-01
EP2490711A1 (fr) 2012-08-29
WO2011047434A1 (fr) 2011-04-28
MX2012004610A (es) 2012-11-12
ES2692377T3 (es) 2018-12-03
EP3095458B1 (fr) 2018-07-25
JP2013508307A (ja) 2013-03-07
PE20121709A1 (es) 2012-12-17
EP3095458A1 (fr) 2016-11-23
PT3095458T (pt) 2018-11-09
BR112012009521A2 (pt) 2016-05-17
KR101936439B1 (ko) 2019-01-08
MX355971B (es) 2018-05-07
US20120251516A1 (en) 2012-10-04
CN107625957A (zh) 2018-01-26
KR20120128124A (ko) 2012-11-26
CN102639145A (zh) 2012-08-15
IL219216A0 (en) 2012-06-28
CL2012001019A1 (es) 2013-07-12

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