SE9500342D0 - Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation - Google Patents

Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation

Info

Publication number
SE9500342D0
SE9500342D0 SE9500342A SE9500342A SE9500342D0 SE 9500342 D0 SE9500342 D0 SE 9500342D0 SE 9500342 A SE9500342 A SE 9500342A SE 9500342 A SE9500342 A SE 9500342A SE 9500342 D0 SE9500342 D0 SE 9500342D0
Authority
SE
Sweden
Prior art keywords
nucleic acid
group
compounds
optionally
acid sequencing
Prior art date
Application number
SE9500342A
Other languages
English (en)
Swedish (sv)
Inventor
Marek Kwiatkowski
Original Assignee
Marek Kwiatkowski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marek Kwiatkowski filed Critical Marek Kwiatkowski
Priority to SE9500342A priority Critical patent/SE9500342D0/xx
Publication of SE9500342D0 publication Critical patent/SE9500342D0/xx
Priority to US08/875,243 priority patent/US6255475B1/en
Priority to JP8523466A priority patent/JPH10513178A/ja
Priority to EP96902039A priority patent/EP0808320B1/en
Priority to PCT/SE1996/000096 priority patent/WO1996023807A1/en
Priority to DE69627314T priority patent/DE69627314T2/de
Priority to CA002212000A priority patent/CA2212000A1/en
Priority to ES96902039T priority patent/ES2197231T3/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE9500342A 1995-01-31 1995-01-31 Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation SE9500342D0 (sv)

Priority Applications (8)

Application Number Priority Date Filing Date Title
SE9500342A SE9500342D0 (sv) 1995-01-31 1995-01-31 Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation
US08/875,243 US6255475B1 (en) 1995-01-31 1996-01-30 Chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation
JP8523466A JPH10513178A (ja) 1995-01-31 1996-01-30 新規な鎖停止剤、核酸配列決定および合成用のその使用、ならびにその製法
EP96902039A EP0808320B1 (en) 1995-01-31 1996-01-30 Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation
PCT/SE1996/000096 WO1996023807A1 (en) 1995-01-31 1996-01-30 Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation
DE69627314T DE69627314T2 (de) 1995-01-31 1996-01-30 Kettenabbruchgruppen, ihre verwendung zur sequenzierung und synthese von nukleinsäuren und verfahren zu ihrer herstellung
CA002212000A CA2212000A1 (en) 1995-01-31 1996-01-30 Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation
ES96902039T ES2197231T3 (es) 1995-01-31 1996-01-30 Nuevos terminadores de cadena, su uso en la secuenciacion y sintesis de acidos nucleicos y metodo para su preparacion.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9500342A SE9500342D0 (sv) 1995-01-31 1995-01-31 Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation

Publications (1)

Publication Number Publication Date
SE9500342D0 true SE9500342D0 (sv) 1995-01-31

Family

ID=20397031

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9500342A SE9500342D0 (sv) 1995-01-31 1995-01-31 Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation

Country Status (8)

Country Link
US (1) US6255475B1 (xx)
EP (1) EP0808320B1 (xx)
JP (1) JPH10513178A (xx)
CA (1) CA2212000A1 (xx)
DE (1) DE69627314T2 (xx)
ES (1) ES2197231T3 (xx)
SE (1) SE9500342D0 (xx)
WO (1) WO1996023807A1 (xx)

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US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
FR2790005B1 (fr) 1999-02-22 2004-01-30 Commissariat Energie Atomique Procede de fabrication de morpholino-nucleotides, et utilisation de ceux-ci pour l'analyse et le marquage de sequences d'acides nucleiques
US6309836B1 (en) 1999-10-05 2001-10-30 Marek Kwiatkowski Compounds for protecting hydroxyls and methods for their use
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US9708358B2 (en) 2000-10-06 2017-07-18 The Trustees Of Columbia University In The City Of New York Massive parallel method for decoding DNA and RNA
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US20030228611A1 (en) * 2002-05-01 2003-12-11 President And Fellows Of Harvard College Nucleic acid memory device
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US11008359B2 (en) 2002-08-23 2021-05-18 Illumina Cambridge Limited Labelled nucleotides
US7414116B2 (en) * 2002-08-23 2008-08-19 Illumina Cambridge Limited Labelled nucleotides
US7345163B2 (en) * 2002-08-28 2008-03-18 Quiatech Ab Process for separating and deprotecting oligonucleotides
US8637650B2 (en) 2003-11-05 2014-01-28 Genovoxx Gmbh Macromolecular nucleotide compounds and methods for using the same
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GB0517097D0 (en) 2005-08-19 2005-09-28 Solexa Ltd Modified nucleosides and nucleotides and uses thereof
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
WO2007120192A2 (en) * 2005-10-27 2007-10-25 The President And Fellows Of Harvard College Methods and compositions for labeling nucleic acids
WO2007053719A2 (en) 2005-10-31 2007-05-10 The Trustees Of Columbia University In The City Of New York Chemically cleavable 3'-o-allyl-dntp-allyl-fluorophore fluorescent nucleotide analogues and related methods
US7982029B2 (en) 2005-10-31 2011-07-19 The Trustees Of Columbia University In The City Of New York Synthesis of four color 3′O-allyl, modified photocleavable fluorescent nucleotides and related methods
US8114636B2 (en) * 2006-02-10 2012-02-14 Life Technologies Corporation Labeling and detection of nucleic acids
US20070249014A1 (en) * 2006-02-10 2007-10-25 Invitrogen Corporation Labeling and detection of post translationally modified proteins
AU2007217657B2 (en) * 2006-02-21 2011-08-04 Huntsman International Llc Process for making a polyisocyanurate composite
FI20065162A0 (fi) * 2006-03-13 2006-03-13 Wallac Oy Terminoivia DNA polymeraasisubstraatteja
US7482444B2 (en) * 2006-03-13 2009-01-27 Wallac Oy Terminating substrates for DNA polymerases
JP2009538123A (ja) * 2006-04-19 2009-11-05 アプライド バイオシステムズ， エルエルシー ゲル非含有ビーズベースの配列決定のための試薬、方法およびライブラリー
WO2008042067A2 (en) 2006-09-28 2008-04-10 Illumina, Inc. Compositions and methods for nucleotide sequencing
WO2008069973A2 (en) 2006-12-01 2008-06-12 The Trustees Of Columbia University In The City Of New York Four-color dna sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators
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EP3431615A3 (en) 2007-10-19 2019-02-20 The Trustees of Columbia University in the City of New York Dna sequencing with non-fluorescent nucleotide reversible terminators cleavable label modified nucleotide terminators
EP2940029B1 (en) 2007-10-19 2023-11-29 The Trustees of Columbia University in the City of New York Design and synthesis of cleavable fluorescent nucleotides as reversible terminators for dna sequencing by synthesis
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Also Published As

Publication number Publication date
ES2197231T3 (es) 2004-01-01
JPH10513178A (ja) 1998-12-15
CA2212000A1 (en) 1996-08-08
EP0808320A1 (en) 1997-11-26
US6255475B1 (en) 2001-07-03
EP0808320B1 (en) 2003-04-09
DE69627314D1 (de) 2003-05-15
DE69627314T2 (de) 2004-03-04
WO1996023807A1 (en) 1996-08-08

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