SE9100860D0 - New use - Google Patents

New use

Info

Publication number
SE9100860D0
SE9100860D0 SE9100860A SE9100860A SE9100860D0 SE 9100860 D0 SE9100860 D0 SE 9100860D0 SE 9100860 A SE9100860 A SE 9100860A SE 9100860 A SE9100860 A SE 9100860A SE 9100860 D0 SE9100860 D0 SE 9100860D0
Authority
SE
Sweden
Prior art keywords
abuse
piperazine
type drugs
new use
opiate
Prior art date
Application number
SE9100860A
Other languages
English (en)
Swedish (sv)
Inventor
A Bjoerk
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Priority to SE9100860A priority Critical patent/SE9100860D0/xx
Publication of SE9100860D0 publication Critical patent/SE9100860D0/xx
Priority to EP92907159A priority patent/EP0538422B1/en
Priority to RU9292016400A priority patent/RU2095062C1/ru
Priority to KR1019920702939A priority patent/KR100196674B1/ko
Priority to HU9203632A priority patent/HU9203632D0/hu
Priority to PCT/SE1992/000182 priority patent/WO1992016211A1/en
Priority to US07/949,869 priority patent/US5434156A/en
Priority to JP50658392A priority patent/JP3221611B2/ja
Priority to IE092092A priority patent/IE920920A1/en
Priority to ES92907159T priority patent/ES2154261T3/es
Priority to DK92907159T priority patent/DK0538422T3/da
Priority to AU14280/92A priority patent/AU653797B2/en
Priority to DE69231680T priority patent/DE69231680T2/de
Priority to RO92-01457A priority patent/RO109702B1/ro
Priority to SK3449-92A priority patent/SK279237B6/sk
Priority to BR9204969A priority patent/BR9204969A/pt
Priority to AT92907159T priority patent/ATE199057T1/de
Priority to PT100279A priority patent/PT100279B/pt
Priority to CA002083505A priority patent/CA2083505C/en
Priority to CS923449A priority patent/CZ282222B6/cs
Priority to HU9203632A priority patent/HU217833B/hu
Priority to BG97108A priority patent/BG61829B1/bg
Priority to NO924502A priority patent/NO301311B1/no
Priority to EE9400358A priority patent/EE02973B1/xx
Priority to US08/428,899 priority patent/US5618817A/en
Priority to GR20010400653T priority patent/GR3035805T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE9100860A 1991-03-22 1991-03-22 New use SE9100860D0 (sv)

Priority Applications (26)

Application Number Priority Date Filing Date Title
SE9100860A SE9100860D0 (sv) 1991-03-22 1991-03-22 New use
HU9203632A HU217833B (hu) 1991-03-22 1992-03-23 Eljárás difenil-butil-piperazin-karboxamidokat tartalmazó, mértéktelen szerfogyasztásból eredő betegségek kezelésére alkalmas gyógyszerkészítmények előállítására
DE69231680T DE69231680T2 (de) 1991-03-22 1992-03-23 Neue verwendung von diphenylbutyl-piperazincarboxamiden zur behandlung von störungen im zusammenhang mit der verwendung giftiger stoffen
SK3449-92A SK279237B6 (sk) 1991-03-22 1992-03-23 Použitie amperozidu, 4-[4,4-bis(4-fluórfenyl)butyl
KR1019920702939A KR100196674B1 (ko) 1991-03-22 1992-03-23 디페닐부틸-피페라진카르복사미드를 이용한 물질 남용 장애의 치료방법 및 그를 함유하는 약제학적 조성물
HU9203632A HU9203632D0 (en) 1991-03-22 1992-03-23 Method for utilization of diphenyl-butyl-piperazine-carboxamides in treatment of diseases of material-dependency
PCT/SE1992/000182 WO1992016211A1 (en) 1991-03-22 1992-03-23 New use of diphenylbutyl-piperazinecarboxamides in the treatment of substance disorders
US07/949,869 US5434156A (en) 1991-03-22 1992-03-23 Use of diphenylbutyl-piperazinecarboxamides in the treatment of substance disorders
JP50658392A JP3221611B2 (ja) 1991-03-22 1992-03-23 物質乱用障害の治療用医薬組成物
IE092092A IE920920A1 (en) 1991-03-22 1992-03-23 Method and means for treatment of substance abuse disorders
ES92907159T ES2154261T3 (es) 1991-03-22 1992-03-23 Nuevo uso de difenilbutil-piperazincarboxamidas en el tratamiento de trastornos por abuso de sustancias.
DK92907159T DK0538422T3 (da) 1991-03-22 1992-03-23 Hidtil ukendt anvendelse af diphenylbutyl-piperazincarboxamider til behandling af stofmisbrugslidelser
AU14280/92A AU653797B2 (en) 1991-03-22 1992-03-23 New use of diphenylbutyl-piperazinecarboxamides in the treatment of substance disorders
EP92907159A EP0538422B1 (en) 1991-03-22 1992-03-23 New use of diphenylbutylpiperazinecarboxamides in the treatment of substance disorders
RO92-01457A RO109702B1 (ro) 1991-03-22 1992-03-23 Metoda de tratament a imbolnavirilor rezultate din abuz de substante
RU9292016400A RU2095062C1 (ru) 1991-03-22 1992-03-23 Блокатор синдрома отмены, являющегося результатом привыкания к чрезмерному потреблению лекарств или веществ, вызывающих привыкание, фармакологическая композиция на его основе и способ облегчения или предотвращения синдрома отмены
BR9204969A BR9204969A (pt) 1991-03-22 1992-03-23 Novo emprego de diphenylbutyl-piperazinecarboxam ides no tratamento de disturbios provocados por substancias
AT92907159T ATE199057T1 (de) 1991-03-22 1992-03-23 Neue verwendung von diphenylbutyl- piperazincarboxamiden zur behandlung von störungen im zusammenhang mit der verwendung giftiger stoffen
PT100279A PT100279B (pt) 1991-03-22 1992-03-23 Utilizacao de difenilbutilpiperazinocarboxamidas na presenca de composicoes farmaceuticas para o tratmento de perturbacoes provocadas por abuso de drogas em pacientes viciados e processo de tratamento que as emprega
CA002083505A CA2083505C (en) 1991-03-22 1992-03-23 New use of diphenylbutyl-piperazinecarboxamides in the treatment of substance disorders
CS923449A CZ282222B6 (cs) 1991-03-22 1992-03-23 Použití difenylbutylpiperazinkarboxamidů pro příp ravu léčiv pro léčení poruch vyplývajících ze zneužívání různých látek
BG97108A BG61829B1 (bg) 1991-03-22 1992-11-20 Използване на дифенилбутилпиперазинкарбоксамид при лечение насмущения, предизвикани от злоупотреба с вещества
NO924502A NO301311B1 (no) 1991-03-22 1992-11-23 Ny anvendelse av difenylbutyl-piperazinkarboksamider ved behandling av stoffmisbruklidelser
EE9400358A EE02973B1 (et) 1991-03-22 1994-11-17 Difenüülbutüül-piperasiinkarboksamiidi kasutamine narkomaaniavastase ravimi valmistamiseks ja farmatseutiline kompositsioon
US08/428,899 US5618817A (en) 1991-03-22 1995-04-25 Use of diphenylbutyl-piperazinecarboxamides in the treatment of substance disorders
GR20010400653T GR3035805T3 (en) 1991-03-22 2001-04-27 New use of diphenylbutylpiperazinecarboxamides in the treatment of substance disorders.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9100860A SE9100860D0 (sv) 1991-03-22 1991-03-22 New use

Publications (1)

Publication Number Publication Date
SE9100860D0 true SE9100860D0 (sv) 1991-03-22

Family

ID=20382242

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9100860A SE9100860D0 (sv) 1991-03-22 1991-03-22 New use

Country Status (24)

Country Link
US (2) US5434156A (ja)
EP (1) EP0538422B1 (ja)
JP (1) JP3221611B2 (ja)
KR (1) KR100196674B1 (ja)
AT (1) ATE199057T1 (ja)
AU (1) AU653797B2 (ja)
BG (1) BG61829B1 (ja)
BR (1) BR9204969A (ja)
CA (1) CA2083505C (ja)
CZ (1) CZ282222B6 (ja)
DE (1) DE69231680T2 (ja)
DK (1) DK0538422T3 (ja)
EE (1) EE02973B1 (ja)
ES (1) ES2154261T3 (ja)
GR (1) GR3035805T3 (ja)
HU (2) HU9203632D0 (ja)
IE (1) IE920920A1 (ja)
NO (1) NO301311B1 (ja)
PT (1) PT100279B (ja)
RO (1) RO109702B1 (ja)
RU (1) RU2095062C1 (ja)
SE (1) SE9100860D0 (ja)
SK (1) SK279237B6 (ja)
WO (1) WO1992016211A1 (ja)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9100860D0 (sv) * 1991-03-22 1991-03-22 Kabi Pharmacia Ab New use
SE9201239D0 (sv) * 1992-04-21 1992-04-21 Kabi Pharmacia Ab Agents for treating substance abuse disorders
JP3571114B2 (ja) * 1995-07-11 2004-09-29 ポーラ化成工業株式会社 麻薬拮抗剤
US6265393B1 (en) 1998-08-07 2001-07-24 Heinrichs William Leroy Prevention of endometriosis signs or symptons
US6090780A (en) * 1999-04-07 2000-07-18 Chandon Prasad Histidyl-proline diketopiperazine and method of use
USRE39921E1 (en) 1999-10-07 2007-11-13 Smithkline Beecham Corporation Chemical compounds
GB9923748D0 (en) 1999-10-07 1999-12-08 Glaxo Group Ltd Chemical compounds
GB0025354D0 (en) 2000-10-17 2000-11-29 Glaxo Group Ltd Chemical compounds
US20050192271A1 (en) * 2003-07-15 2005-09-01 Hythiam, Inc. Use of selective chloride channel modulators to treat alcohol and/or stimulant substance abuse
NZ527583A (en) * 2001-01-17 2006-03-31 Hythiam Inc Use of flumazenil in developing a drug for the treatment of alcohol dependence
US7183410B2 (en) * 2001-08-02 2007-02-27 Bidachem S.P.A. Stable polymorph of flibanserin
US20030060475A1 (en) * 2001-08-10 2003-03-27 Boehringer Ingelheim Pharma Kg Method of using flibanserin for neuroprotection
UA78974C2 (en) 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
GB0203020D0 (en) 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
GB0203022D0 (en) 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
EP1472222A1 (en) 2002-02-08 2004-11-03 Glaxo Group Limited Piperidylcarboxamide derivatives and their use in the treatment of tachykinim-mediated diseases
NZ551340A (en) * 2004-04-22 2010-10-29 Boehringer Ingelheim Int Pharmaceutical composition comprising flibanserin and a melanocortin agonist for the treatment of premenstrual disorder or sexual aversion disorder
US20050239798A1 (en) * 2004-04-22 2005-10-27 Boehringer Ingelheim Pharmaceuticals, Inc. Method for the treatment of premenstrual and other female sexual disorders
US20060025420A1 (en) * 2004-07-30 2006-02-02 Boehringer Ingelheimn International GmbH Pharmaceutical compositions for the treatment of female sexual disorders
JP2008511569A (ja) * 2004-09-03 2008-04-17 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 注意欠如活動過多障害の治療方法
WO2006096435A1 (en) * 2005-03-04 2006-09-14 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for the treatment and/or prevention of depression
WO2006096439A2 (en) * 2005-03-04 2006-09-14 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for the treatment and/or prevention of schizophrenia and related diseases
JP2008531714A (ja) * 2005-03-04 2008-08-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 不安障害の治療用及び／又は予防用の医薬組成物
EP1904182A2 (en) * 2005-05-06 2008-04-02 Boehringer Ingelheim International GmbH Method for the treatment of drug abuse with flibanserin
CA2608713A1 (en) * 2005-05-19 2006-11-23 Boehringer Ingelheim International Gmbh Method for the treatment of sexual dysfunctions due to medical conditions
WO2006125042A1 (en) * 2005-05-19 2006-11-23 Boehringer Ingelheim International Gmbh Method for the treatment of drug-induced sexual dysfunction
JP2009503020A (ja) 2005-08-03 2009-01-29 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 肥満症の治療におけるフリバンセリンの使用
JP2009513604A (ja) * 2005-10-29 2009-04-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 月経前障害及び他の女性の性的障害治療用のベンゾイミダゾロン誘導体
US20070123540A1 (en) * 2005-10-29 2007-05-31 Angelo Ceci Sexual desire enhancing medicaments comprising benzimidazolone derivatives
US20070105869A1 (en) * 2005-11-08 2007-05-10 Stephane Pollentier Use of flibanserin for the treatment of pre-menopausal sexual desire disorders
KR20090005371A (ko) * 2006-05-09 2009-01-13 베링거 인겔하임 인터내셔날 게엠베하 폐경후 성욕 장애의 치료를 위한 플리반세린의 용도
EP2037927B1 (en) 2006-06-30 2010-01-27 Boehringer Ingelheim International GmbH Flibanserin for the treatment of urinary incontinence and related diseases
EP2043648A1 (en) * 2006-07-14 2009-04-08 Boehringer Ingelheim International GmbH Use of flibanserin for the treatment of sexual disorders in females
CL2007002214A1 (es) * 2006-08-14 2008-03-07 Boehringer Ingelheim Int Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp
JP5793828B2 (ja) 2006-08-14 2015-10-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング フリバンセリンの製剤及びその製造方法
EP2056797A2 (en) * 2006-08-25 2009-05-13 Boehringer Ingelheim International GmbH Controlled release system and method for manufacturing the same
UY31335A1 (es) * 2007-09-12 2009-04-30 Tratamiento de sintomas vasomotores

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO154582C (no) * 1978-10-20 1986-11-05 Ferrosan Ab Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.
SE9100860D0 (sv) * 1991-03-22 1991-03-22 Kabi Pharmacia Ab New use

Also Published As

Publication number Publication date
BG61829B1 (bg) 1998-07-31
HU217833B (hu) 2000-04-28
CA2083505A1 (en) 1992-09-23
GR3035805T3 (en) 2001-07-31
SK279237B6 (sk) 1998-08-05
KR930700108A (ko) 1993-03-13
IE920920A1 (en) 1992-09-23
NO924502L (no) 1992-11-23
US5434156A (en) 1995-07-18
KR100196674B1 (ko) 1999-06-15
NO301311B1 (no) 1997-10-13
CZ344992A3 (en) 1994-02-16
EP0538422A1 (en) 1993-04-28
BG97108A (bg) 1994-03-24
BR9204969A (pt) 1993-07-27
WO1992016211A1 (en) 1992-10-01
AU653797B2 (en) 1994-10-13
ES2154261T3 (es) 2001-04-01
HU9203632D0 (en) 1993-03-29
DE69231680D1 (de) 2001-03-15
DK0538422T3 (da) 2001-05-07
RU2095062C1 (ru) 1997-11-10
CA2083505C (en) 2003-06-10
EE02973B1 (et) 1997-04-15
HUT64696A (en) 1994-02-28
PT100279B (pt) 1999-06-30
EP0538422B1 (en) 2001-02-07
US5618817A (en) 1997-04-08
CZ282222B6 (cs) 1997-06-11
ATE199057T1 (de) 2001-02-15
JP3221611B2 (ja) 2001-10-22
NO924502D0 (no) 1992-11-23
SK344992A3 (en) 1995-11-08
PT100279A (pt) 1993-07-30
RO109702B1 (ro) 1995-05-30
DE69231680T2 (de) 2001-06-07
JPH05507731A (ja) 1993-11-04
AU1428092A (en) 1992-10-21

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