SE8902603L - (rs)-2-(2,3-dihydro-5-hydroxi-4,6,7-trimetylbensofuranyl) aettiksyror och 2-(2,3-dihydro-5-acyloxi-4,6,7-trimetylbensofuranyl) aettiksyror och estrar daerav, anvaendbara saasom slemreglerande och antiischemiska laekemedeloch foerfarande foer framstaellning daerav - Google Patents

(rs)-2-(2,3-dihydro-5-hydroxi-4,6,7-trimetylbensofuranyl) aettiksyror och 2-(2,3-dihydro-5-acyloxi-4,6,7-trimetylbensofuranyl) aettiksyror och estrar daerav, anvaendbara saasom slemreglerande och antiischemiska laekemedeloch foerfarande foer framstaellning daerav

Info

Publication number
SE8902603L
SE8902603L SE8902603A SE8902603A SE8902603L SE 8902603 L SE8902603 L SE 8902603L SE 8902603 A SE8902603 A SE 8902603A SE 8902603 A SE8902603 A SE 8902603A SE 8902603 L SE8902603 L SE 8902603L
Authority
SE
Sweden
Prior art keywords
dihydro
benzofuranyl
trimethyl
acetic acids
hydroxy
Prior art date
Application number
SE8902603A
Other languages
English (en)
Other versions
SE8902603D0 (sv
SE469652B (sv
Inventor
M Brufani
Original Assignee
Foscama Biomed Chim Farma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Foscama Biomed Chim Farma filed Critical Foscama Biomed Chim Farma
Publication of SE8902603D0 publication Critical patent/SE8902603D0/sv
Publication of SE8902603L publication Critical patent/SE8902603L/sv
Publication of SE469652B publication Critical patent/SE469652B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
SE8902603A 1988-08-01 1989-07-26 (rs)-2-(2,3-dihydro-5-hydroxi-4,6,7-trimetylbensofuranyl) aettiksyror och 2-(2,3-dihydro-5-acyloxi-4,6,7- trimetylbensofuranyl) aettiksyror och estrar daerav, anvaendbara saasom slemreglerande och antiischemiska laekemedel och foerfarande foer framstaellning daerav SE469652B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8821603A IT1229482B (it) 1988-08-01 1988-08-01 Acidi (rs) 2 (2,3 diidro 5 idrossi 4,6,7 trimetilbenzofuranil) acetico e 2 (2,3 diidro 5 acilossi 4,6,7 trimetilbenzofuranil) acetici e loro esteri, utili come farmaci mucoregolatori ed antiischemici.

Publications (3)

Publication Number Publication Date
SE8902603D0 SE8902603D0 (sv) 1989-07-26
SE8902603L true SE8902603L (sv) 1990-02-02
SE469652B SE469652B (sv) 1993-08-16

Family

ID=11184201

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8902603A SE469652B (sv) 1988-08-01 1989-07-26 (rs)-2-(2,3-dihydro-5-hydroxi-4,6,7-trimetylbensofuranyl) aettiksyror och 2-(2,3-dihydro-5-acyloxi-4,6,7- trimetylbensofuranyl) aettiksyror och estrar daerav, anvaendbara saasom slemreglerande och antiischemiska laekemedel och foerfarande foer framstaellning daerav

Country Status (15)

Country Link
US (2) US4999350A (sv)
JP (1) JPH0278675A (sv)
KR (1) KR0129526B1 (sv)
CN (1) CN1034574C (sv)
BE (1) BE1003255A5 (sv)
CA (1) CA1324134C (sv)
CH (1) CH679583A5 (sv)
DE (1) DE3925496A1 (sv)
ES (1) ES2014188A6 (sv)
FR (1) FR2634766A1 (sv)
GB (1) GB2221463B (sv)
HK (1) HK48693A (sv)
IT (1) IT1229482B (sv)
SE (1) SE469652B (sv)
SG (1) SG26693G (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1231341B (it) * 1989-08-18 1991-11-28 Foscama Biomed Chim Farma 2,3 diidro 5 ossi 4,6,7 trimetilbenzofurani 2 (rs) sostituiti, utili come farmaci antiossidanti con proprieta' mucoregolatrici e antiischemiche.
IT1239946B (it) * 1990-03-12 1993-11-27 Biomedica Foscama Industria Chimicofarmaceutica Procedimento per la sintesi degli acidi 5-acilossi e 5-alcossi-2,3-diidro-4,6,7-trimetil-2-(rs)-benzofuranacetici
US5240956A (en) * 1990-11-07 1993-08-31 Cortech, Inc. Ester inhibitors
EP0550292A1 (en) * 1992-01-02 1993-07-07 Merrell Dow Pharmaceuticals Inc. Tissue protective tocopherol analogs
US5510373A (en) * 1992-04-06 1996-04-23 Merrell Pharmaceuticals Inc. Cardioprotective agents
EP0635009B1 (en) * 1992-04-06 1997-09-17 Merrell Pharmaceuticals Inc. Novel derivatives of 2,3-dihydro-2,2,4,6,7-pentaalkyl-5-benzofuranols
US5721233A (en) * 1992-04-06 1998-02-24 Merrell Pharmaceuticals Inc. Derivatives of 2,3-dihydro benzofuranols
TW393475B (en) * 1992-10-16 2000-06-11 Chugai Pharmaceutical Co Ltd 4-alkoxyl-2,6-di-t-butyl phenol derivatives
IT1289494B1 (it) * 1996-12-20 1998-10-15 Biomedica Foscana Ind Chimico Acidi 5-idrossi- e 5-acilossi-2,3-diidro-4,6,7-trimetil-2- benzofuranaceti e loro esteri per il trattamento e la prevenzione
IT1320131B1 (it) * 2000-12-21 2003-11-18 Foscama Biomed Chim Farma Uso degli acidi 5-idrossi e 5-acilossi-2,3-diidro-4,6,7-trimetil-2-benzofuranacetici e loro esteri come cicatrizzanti delle lesioni

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6065063A (ja) * 1983-09-20 1985-04-13 Matsunaga Kagaku Kogyo Kk 難燃化剤
US4537903A (en) * 1983-10-12 1985-08-27 Merck & Co., Inc. Substituted cinnamyl-2,3-dihydrobenzofuran and analogs useful as anti-inflammatory agents
US4918092A (en) * 1983-12-21 1990-04-17 Merck Frosst Canada, Inc. Leukotriene antagonists
CA1281325C (en) * 1984-06-20 1991-03-12 Patrice C. Belanger Benzofuran derivatives
JPS6388173A (ja) * 1986-09-30 1988-04-19 Kuraray Co Ltd ２，３−ジヒドロベンゾフラン誘導体
EP0273647B1 (en) * 1986-12-27 1992-03-11 Takeda Chemical Industries, Ltd. Coumaran derivatives, their production and use
JP2855340B2 (ja) * 1988-06-10 1999-02-10 武田薬品工業株式会社 ２―置換クマラン誘導体

Also Published As

Publication number Publication date
SE8902603D0 (sv) 1989-07-26
SG26693G (en) 1993-05-21
GB8917515D0 (en) 1989-09-13
DE3925496A1 (de) 1990-02-22
JPH0278675A (ja) 1990-03-19
IT1229482B (it) 1991-09-03
HK48693A (en) 1993-05-27
US5041568A (en) 1991-08-20
BE1003255A5 (fr) 1992-02-11
KR0129526B1 (ko) 1998-04-09
GB2221463B (en) 1992-03-25
ES2014188A6 (es) 1990-06-16
CN1034574C (zh) 1997-04-16
IT8821603A0 (it) 1988-08-01
KR900003145A (ko) 1990-03-23
FR2634766A1 (fr) 1990-02-02
FR2634766B1 (sv) 1994-08-19
DE3925496C2 (sv) 1992-04-30
US4999350A (en) 1991-03-12
CN1042354A (zh) 1990-05-23
GB2221463A (en) 1990-02-07
CH679583A5 (sv) 1992-03-13
SE469652B (sv) 1993-08-16
CA1324134C (en) 1993-11-09

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