ATE107648T1 - 1-carbacephalosporin-antibiotika. - Google Patents

1-carbacephalosporin-antibiotika.

Info

Publication number
ATE107648T1
ATE107648T1 AT89300640T AT89300640T ATE107648T1 AT E107648 T1 ATE107648 T1 AT E107648T1 AT 89300640 T AT89300640 T AT 89300640T AT 89300640 T AT89300640 T AT 89300640T AT E107648 T1 ATE107648 T1 AT E107648T1
Authority
AT
Austria
Prior art keywords
antibiotics
carbacephalosporin
carbacephalosporin antibiotics
dethia
carba
Prior art date
Application number
AT89300640T
Other languages
English (en)
Inventor
Gwendolyn Kay Cook
John Hampton Mcdonald Iii
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE107648T1 publication Critical patent/ATE107648T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • C07D463/18Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
AT89300640T 1988-01-25 1989-01-24 1-carbacephalosporin-antibiotika. ATE107648T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14747188A 1988-01-25 1988-01-25

Publications (1)

Publication Number Publication Date
ATE107648T1 true ATE107648T1 (de) 1994-07-15

Family

ID=22521694

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89300640T ATE107648T1 (de) 1988-01-25 1989-01-24 1-carbacephalosporin-antibiotika.

Country Status (5)

Country Link
EP (1) EP0327239B1 (de)
JP (1) JPH021487A (de)
AT (1) ATE107648T1 (de)
DE (1) DE68916275T2 (de)
ES (1) ES2055030T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5179088A (en) * 1990-02-12 1993-01-12 Eli Lilly And Company 1-carba(dethia)cephalosporin antibiotics
US5272265A (en) * 1990-02-12 1993-12-21 Eli Lilly And Company 3-(substituted or unsubstituted) thiazolo-1-carba (1-dethia)cephems
US5169843A (en) * 1990-10-22 1992-12-08 Bristol-Myers Squibb Company Antibiotic C-3 cyclobutenedione substituted (1-carba) cephalosporin compounds, cmpositions, and methods of use thereof
US5206360A (en) * 1990-10-22 1993-04-27 Bristol-Myers Squibb Company Intermediates for cyclobutenedione substituted (1-carba)cephalosporin compounds
US5106842A (en) * 1990-10-22 1992-04-21 Bristol-Myers Squibb Co. Antibiotic c-3 cyclobutenedione substituted (1-carba)cephalosporin compounds, compositions, and methods of use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013651A (en) * 1975-05-12 1977-03-22 Eli Lilly And Company 3-substituted amino-cephalosporins

Also Published As

Publication number Publication date
JPH021487A (ja) 1990-01-05
DE68916275T2 (de) 1994-11-17
EP0327239B1 (de) 1994-06-22
DE68916275D1 (de) 1994-07-28
EP0327239A1 (de) 1989-08-09
ES2055030T3 (es) 1994-08-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee