DE69016719D1 - Cephalosporinderivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate und Zwischenverbindungen. - Google Patents

Cephalosporinderivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate und Zwischenverbindungen.

Info

Publication number
DE69016719D1
DE69016719D1 DE69016719T DE69016719T DE69016719D1 DE 69016719 D1 DE69016719 D1 DE 69016719D1 DE 69016719 T DE69016719 T DE 69016719T DE 69016719 T DE69016719 T DE 69016719T DE 69016719 D1 DE69016719 D1 DE 69016719D1
Authority
DE
Germany
Prior art keywords
processes
intermediates
preparation
cephalosporin derivatives
pharmaceutical preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69016719T
Other languages
English (en)
Other versions
DE69016719T2 (de
Inventor
Clive Leslie Branch
Angela Wendy Guest
Stephen Christopher Finch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898919944A external-priority patent/GB8919944D0/en
Priority claimed from GB909010264A external-priority patent/GB9010264D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of DE69016719D1 publication Critical patent/DE69016719D1/de
Publication of DE69016719T2 publication Critical patent/DE69016719T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69016719T 1989-09-04 1990-08-30 Cephalosporinderivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate und Zwischenverbindungen. Expired - Fee Related DE69016719T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898919944A GB8919944D0 (en) 1989-09-04 1989-09-04 Novel compounds
GB909010264A GB9010264D0 (en) 1990-05-08 1990-05-08 Novel compounds

Publications (2)

Publication Number Publication Date
DE69016719D1 true DE69016719D1 (de) 1995-03-23
DE69016719T2 DE69016719T2 (de) 1995-06-01

Family

ID=26295866

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69016719T Expired - Fee Related DE69016719T2 (de) 1989-09-04 1990-08-30 Cephalosporinderivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate und Zwischenverbindungen.

Country Status (9)

Country Link
US (1) US5275816A (de)
EP (1) EP0416810B1 (de)
JP (1) JPH03141287A (de)
KR (1) KR910006300A (de)
AT (1) ATE118215T1 (de)
AU (1) AU6210790A (de)
CA (1) CA2024396A1 (de)
DE (1) DE69016719T2 (de)
IE (1) IE903171A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5403835A (en) * 1986-03-20 1995-04-04 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives
MY106991A (en) * 1989-09-04 1995-08-30 Pfizer Novel cephalosporin derivatives or compounds
TW446707B (en) * 1996-10-22 2001-07-21 Hoffmann La Roche Cephalosporin pyridinium derivatives
EP0841339B1 (de) 1996-11-06 2007-02-21 Basilea Pharmaceutica AG Vinylpyrrolidinon-Cephalosporin-Derivate
US6329363B1 (en) * 1997-12-12 2001-12-11 Eli Lilly And Company Cephalosporin antibiotics
US6369049B1 (en) 1998-04-30 2002-04-09 Eli Lilly And Company Treatment of mastitis
CN103619853A (zh) * 2011-06-27 2014-03-05 盐野义制药株式会社 具有吡啶鎓基的头孢烯化合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3176517D1 (en) * 1980-04-24 1987-12-17 Beecham Group Plc Beta-lactam compounds, their preparation and use
DE3278878D1 (en) * 1981-07-25 1988-09-15 Beecham Group Plc Beta-lactam antibacterial agents
EP0115405B1 (de) * 1983-01-21 1987-06-10 Beecham Group Plc Verfahren zur Herstellung von Beta-Lactam-Verbindungen
GR79789B (de) * 1983-01-24 1984-10-31 Beecham Group Plc
DE3479731D1 (en) * 1983-07-07 1989-10-19 Beecham Group Plc Substituted phenylglycine derivatives of beta-lactam antibiotics
FI82471C (fi) * 1984-01-26 1991-03-11 Beecham Group Plc Foerfarande foer framstaellning av farmakologiskt aktiva 6-metylenpenemderivater.
EP0219926A3 (de) * 1985-06-25 1988-08-31 Beecham Group Plc Cephalosporine, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
EP0211656A3 (de) * 1985-08-10 1988-03-09 Beecham Group Plc Cephalosporinverbindungen, Verfahren zu ihrer Herstellung und sie enthaltende Präparate
JPS63107989A (ja) * 1986-06-04 1988-05-12 Tanabe Seiyaku Co Ltd セファロスポリン化合物
GB8722477D0 (en) * 1987-09-24 1987-10-28 Beecham Group Plc Compounds
US5134138A (en) * 1989-07-18 1992-07-28 Shionogi & Co., Ltd. Phenacylpyridiniothiocephalosporins

Also Published As

Publication number Publication date
EP0416810A2 (de) 1991-03-13
EP0416810A3 (en) 1992-04-01
DE69016719T2 (de) 1995-06-01
ATE118215T1 (de) 1995-02-15
CA2024396A1 (en) 1991-03-05
US5275816A (en) 1994-01-04
AU6210790A (en) 1991-03-07
KR910006300A (ko) 1991-04-29
IE903171A1 (en) 1991-03-13
EP0416810B1 (de) 1995-02-08
JPH03141287A (ja) 1991-06-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee
8327 Change in the person/name/address of the patent owner

Owner name: PFIZER, INC. (N.D.GES.D. STAATES DELAWARE), NEW YO