ES2055030T3 - Antibioticos de 1-carbacefalosporina. - Google Patents

Antibioticos de 1-carbacefalosporina.

Info

Publication number
ES2055030T3
ES2055030T3 ES89300640T ES89300640T ES2055030T3 ES 2055030 T3 ES2055030 T3 ES 2055030T3 ES 89300640 T ES89300640 T ES 89300640T ES 89300640 T ES89300640 T ES 89300640T ES 2055030 T3 ES2055030 T3 ES 2055030T3
Authority
ES
Spain
Prior art keywords
antibiotics
carbacefalosporina
dethia
carba
cephem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89300640T
Other languages
English (en)
Inventor
Gwendolyn Kay Cook
John Hampton Mcdonald Iii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2055030T3 publication Critical patent/ES2055030T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SE PRESENTAN ACIDOS 7 BETA - ACILAMINO - 3 - (AMONIO CUATERNARIO) - 1 - CARBO (1 - DETIA) - 3 - CEFEM - 4 - CARBOXILICOS Y DERIVADOS COMO ANTIBIOTICOS UTILES EN EL TRATAMIENTO DE INFECCIONES EN EL HOMBRE Y EN ANIMALES. TAMBIEN SE PRESENTAN FORMULACIONES Y PRODUCTOS INTERMEDIOS PARA SU PREPARACION.
ES89300640T 1988-01-25 1989-01-24 Antibioticos de 1-carbacefalosporina. Expired - Lifetime ES2055030T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14747188A 1988-01-25 1988-01-25

Publications (1)

Publication Number Publication Date
ES2055030T3 true ES2055030T3 (es) 1994-08-16

Family

ID=22521694

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89300640T Expired - Lifetime ES2055030T3 (es) 1988-01-25 1989-01-24 Antibioticos de 1-carbacefalosporina.

Country Status (5)

Country Link
EP (1) EP0327239B1 (es)
JP (1) JPH021487A (es)
AT (1) ATE107648T1 (es)
DE (1) DE68916275T2 (es)
ES (1) ES2055030T3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5179088A (en) * 1990-02-12 1993-01-12 Eli Lilly And Company 1-carba(dethia)cephalosporin antibiotics
US5272265A (en) * 1990-02-12 1993-12-21 Eli Lilly And Company 3-(substituted or unsubstituted) thiazolo-1-carba (1-dethia)cephems
US5169843A (en) * 1990-10-22 1992-12-08 Bristol-Myers Squibb Company Antibiotic C-3 cyclobutenedione substituted (1-carba) cephalosporin compounds, cmpositions, and methods of use thereof
US5106842A (en) * 1990-10-22 1992-04-21 Bristol-Myers Squibb Co. Antibiotic c-3 cyclobutenedione substituted (1-carba)cephalosporin compounds, compositions, and methods of use thereof
US5206360A (en) * 1990-10-22 1993-04-27 Bristol-Myers Squibb Company Intermediates for cyclobutenedione substituted (1-carba)cephalosporin compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013651A (en) * 1975-05-12 1977-03-22 Eli Lilly And Company 3-substituted amino-cephalosporins

Also Published As

Publication number Publication date
DE68916275T2 (de) 1994-11-17
JPH021487A (ja) 1990-01-05
EP0327239A1 (en) 1989-08-09
EP0327239B1 (en) 1994-06-22
ATE107648T1 (de) 1994-07-15
DE68916275D1 (de) 1994-07-28

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