IT1239946B - Procedimento per la sintesi degli acidi 5-acilossi e 5-alcossi-2,3-diidro-4,6,7-trimetil-2-(rs)-benzofuranacetici - Google Patents

Procedimento per la sintesi degli acidi 5-acilossi e 5-alcossi-2,3-diidro-4,6,7-trimetil-2-(rs)-benzofuranacetici

Info

Publication number
IT1239946B
IT1239946B IT19644A IT1964490A IT1239946B IT 1239946 B IT1239946 B IT 1239946B IT 19644 A IT19644 A IT 19644A IT 1964490 A IT1964490 A IT 1964490A IT 1239946 B IT1239946 B IT 1239946B
Authority
IT
Italy
Prior art keywords
benzofuranacetici
alcoxy
acyloxy
dihydro
trimethyl
Prior art date
Application number
IT19644A
Other languages
English (en)
Other versions
IT9019644A1 (it
IT9019644A0 (it
Inventor
Stefano Ceccarelli
Vellis Patrizia De
Romolo Scuri
Sergio Zanarella
Original Assignee
Biomedica Foscama Industria Chimicofarmaceutica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomedica Foscama Industria Chimicofarmaceutica filed Critical Biomedica Foscama Industria Chimicofarmaceutica
Publication of IT9019644A0 publication Critical patent/IT9019644A0/it
Priority to IT19644A priority Critical patent/IT1239946B/it
Priority to CA002037683A priority patent/CA2037683A1/en
Priority to EP91103588A priority patent/EP0446809A1/en
Priority to HU91795A priority patent/HU208125B/hu
Priority to SU914894945A priority patent/RU2035459C1/ru
Priority to CN91101488A priority patent/CN1054767A/zh
Priority to KR1019910003885A priority patent/KR910016733A/ko
Priority to JP3073919A priority patent/JPH04217970A/ja
Publication of IT9019644A1 publication Critical patent/IT9019644A1/it
Application granted granted Critical
Publication of IT1239946B publication Critical patent/IT1239946B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
IT19644A 1990-03-12 1990-03-12 Procedimento per la sintesi degli acidi 5-acilossi e 5-alcossi-2,3-diidro-4,6,7-trimetil-2-(rs)-benzofuranacetici IT1239946B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT19644A IT1239946B (it) 1990-03-12 1990-03-12 Procedimento per la sintesi degli acidi 5-acilossi e 5-alcossi-2,3-diidro-4,6,7-trimetil-2-(rs)-benzofuranacetici
CA002037683A CA2037683A1 (en) 1990-03-12 1991-03-06 Process for the synthesis of 5-acyloxy and 5-alkoxy-2,3-dihydro-4,6,7-trimethyl-2-(rs)- benzofuranacetic acids
EP91103588A EP0446809A1 (en) 1990-03-12 1991-03-08 New process for the synthesis of 5-acyloxy and 5-alkoxy-2,3-dihydro-4,6,7-trimethyl-2-(RS)-benzofuranacetic acids
SU914894945A RU2035459C1 (ru) 1990-03-12 1991-03-11 Способ получения 5-оксипроизводных 2,3-дигидро-4,6,7-триметил-2-(rs)-бензофурануксусной кислоты
HU91795A HU208125B (en) 1990-03-12 1991-03-11 Process for producing 2,3-dihydro-4,6,7-trimethyl-2-(rs)-benzofuranacetic acid derivatives
CN91101488A CN1054767A (zh) 1990-03-12 1991-03-12 合成5-酰氧基和5-烷氧基-2，3-二氢-4，6，7-三甲基-2-(rs)-苯并呋喃乙酸的新方法
KR1019910003885A KR910016733A (ko) 1990-03-12 1991-03-12 5-아실옥시 및 5-알콕시-2,3-디히드로-4,6,7-트리메틸-2-(rs)-벤조푸란 아세트산의 제조방법
JP3073919A JPH04217970A (ja) 1990-03-12 1991-03-12 ５−アシロキシ及び５−アルコキシ−２，３−ジヒドロ−４，６，７−トリメチル−２−（ｒｓ）−ベンゾフラン酢酸類の新規合成方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19644A IT1239946B (it) 1990-03-12 1990-03-12 Procedimento per la sintesi degli acidi 5-acilossi e 5-alcossi-2,3-diidro-4,6,7-trimetil-2-(rs)-benzofuranacetici

Publications (3)

Publication Number Publication Date
IT9019644A0 IT9019644A0 (it) 1990-03-12
IT9019644A1 IT9019644A1 (it) 1991-09-12
IT1239946B true IT1239946B (it) 1993-11-27

Family

ID=11160041

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19644A IT1239946B (it) 1990-03-12 1990-03-12 Procedimento per la sintesi degli acidi 5-acilossi e 5-alcossi-2,3-diidro-4,6,7-trimetil-2-(rs)-benzofuranacetici

Country Status (8)

Country Link
EP (1) EP0446809A1 (it)
JP (1) JPH04217970A (it)
KR (1) KR910016733A (it)
CN (1) CN1054767A (it)
CA (1) CA2037683A1 (it)
HU (1) HU208125B (it)
IT (1) IT1239946B (it)
RU (1) RU2035459C1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3266998B2 (ja) * 1993-09-07 2002-03-18 三菱ウェルファーマ株式会社 １，４−ベンズオキサジン化合物の工業的な製造法
IT1320131B1 (it) * 2000-12-21 2003-11-18 Foscama Biomed Chim Farma Uso degli acidi 5-idrossi e 5-acilossi-2,3-diidro-4,6,7-trimetil-2-benzofuranacetici e loro esteri come cicatrizzanti delle lesioni
US7728155B2 (en) 2003-10-24 2010-06-01 Wyeth Llc Dihydrobenzofuranyl alkanamines and methods for using same as cns agents
US7435837B2 (en) 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3317884A1 (de) * 1983-05-17 1984-11-22 Hoechst Ag, 6230 Frankfurt 5-(4-chlor-3-sulfamoylbenzoyl)-2,3-dihydro-2-benzofurancarbonsaeuren und verfahren zu ihrer herstellung
US4745127A (en) * 1983-10-31 1988-05-17 Merck Frosst Canada, Inc. Benzyl esters of benzofuran-2-carboxylic acids useful as inhibitors of leukotriene biosynthesis
IT1229482B (it) * 1988-08-01 1991-09-03 Foscama Biomed Chim Farma Acidi (rs) 2 (2,3 diidro 5 idrossi 4,6,7 trimetilbenzofuranil) acetico e 2 (2,3 diidro 5 acilossi 4,6,7 trimetilbenzofuranil) acetici e loro esteri, utili come farmaci mucoregolatori ed antiischemici.

Also Published As

Publication number Publication date
EP0446809A1 (en) 1991-09-18
JPH04217970A (ja) 1992-08-07
HU208125B (en) 1993-08-30
CN1054767A (zh) 1991-09-25
IT9019644A1 (it) 1991-09-12
HUT56560A (en) 1991-09-30
CA2037683A1 (en) 1991-09-13
KR910016733A (ko) 1991-11-05
IT9019644A0 (it) 1990-03-12
RU2035459C1 (ru) 1995-05-20

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950227